Prosecution Insights
Last updated: April 19, 2026
Application No. 14/395,482

PREPARATION AND METHOD FOR THE PROPHYLAXIS AND TREATMENT OF OSTEOPOROSIS AND BONE FRACTURES

Final Rejection §112
Filed
Mar 05, 2015
Examiner
HOFFMAN, SUSAN COE
Art Unit
1655
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Parapharm LLC
OA Round
17 (Final)
54%
Grant Probability
Moderate
18-19
OA Rounds
3y 0m
To Grant
80%
With Interview

Examiner Intelligence

Grants 54% of resolved cases
54%
Career Allow Rate
572 granted / 1058 resolved
-5.9% vs TC avg
Strong +26% interview lift
Without
With
+25.7%
Interview Lift
resolved cases with interview
Typical timeline
3y 0m
Avg Prosecution
67 currently pending
Career history
1125
Total Applications
across all art units

Statute-Specific Performance

§101
9.5%
-30.5% vs TC avg
§103
34.8%
-5.2% vs TC avg
§102
17.4%
-22.6% vs TC avg
§112
26.9%
-13.1% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1058 resolved cases

Office Action

§112
DETAILED ACTION 1. The present application is being examined under the pre-AIA first to invent provisions. 2. A request for continued examination under 37 CFR 1.114, including the fee set forth in 37 CFR 1.17(e), was filed in this application after final rejection. Since this application is eligible for continued examination under 37 CFR 1.114, and the fee set forth in 37 CFR 1.17(e) has been timely paid, the finality of the previous Office action has been withdrawn pursuant to 37 CFR 1.114. Applicant's submission filed on October 23, 2025 has been entered. 3. Claims 1-3 are currently pending. 4. In the reply filed on December 14, 2015, applicant elected Group II, now claim 3, without traverse. 5. Claims 1 and 2 are withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to a nonelected invention, there being no allowable generic or linking claim. 6. Claim 3 is examined on the merits. Claim Rejections - 35 USC § 112 The text of those sections of Title 35, U.S. Code not included in this action can be found in a prior Office action. 7. Claim 3 is rejected under 35 U.S.C. 112(a) or 35 U.S.C. 112 (pre-AIA ), first paragraph, as failing to comply with the written description requirement. The claim(s) contains subject matter which was not described in the specification in such a way as to reasonably convey to one skilled in the relevant art that the inventor or a joint inventor, or for pre-AIA the inventor(s), at the time the application was filed, had possession of the claimed invention. Claim 3 has been amended to state that the preparation comprises a daily dose of 25 mg of drone brood, 50 mg of a calcium compound, and 100 IU of vitamins of the D group or its active metabolites. These new limitations introduce new matter into the claims. The original claims and specification teach using 10 mg to 1000 mg of drone brood, 25 mg to 3,000 mg of a calcium compound, and 50 to 1,000,000 IU of vitamin D (with a specific example of 50,000 IU). The original claims and specification do not specifically teach using 25 mg of drone brood, 50 mg of the calcium compound, and 100 IU of D vitamins. Thus, there is a lack of literal basis for these new limitations in the claims. In addition, as discussed in MPEP section 2163.05(II), the broad disclosure of a generic claim or range does not necessarily provide support for each species that would fall within that broad generic range. Thus, even though 25 mg of drone brood, 50 mg of a calcium compound, and 100 IU of vitamins of the D group falls within the broad generic ranges disclosed, there is not considered to be literal or inherent support for each point within that range. Therefore, the limitations of 25 mg of drone brood, 50 mg of a calcium compound, and 100 IU of vitamins of the D group adds new matter to the disclosure. Response to Arguments Applicant does not present any new arguments in regards to the merits of the rejection itself and reiterates previously filed arguments. For responses to those arguments please see the previous Office actions. 8. No claims are allowed. All claims are identical to or patentably indistinct from, or have unity of invention with claims in the application prior to the entry of the submission under 37 CFR 1.114 (that is, restriction (including a lack of unity of invention) would not be proper) and all claims could have been finally rejected on the grounds and art of record in the next Office action if they had been entered in the application prior to entry under 37 CFR 1.114. Accordingly, THIS ACTION IS MADE FINAL even though it is a first action after the filing of a request for continued examination and the submission under 37 CFR 1.114. See MPEP § 706.07(b). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to Susan Hoffman whose telephone number is (571)272-0963. The examiner can normally be reached M-Th 8:30am - 5:00pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Anand Desai can be reached at 571-272-0947. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /SUSAN HOFFMAN/Primary Examiner, Art Unit 1655
Read full office action

Prosecution Timeline

Mar 05, 2015
Application Filed
Jan 06, 2016
Non-Final Rejection — §112
May 09, 2016
Response after Non-Final Action
May 09, 2016
Response Filed
Sep 13, 2016
Response Filed
Nov 18, 2016
Final Rejection — §112
May 22, 2017
Request for Continued Examination
May 23, 2017
Response after Non-Final Action
Jun 19, 2017
Final Rejection — §112
Dec 20, 2017
Request for Continued Examination
Dec 27, 2017
Response after Non-Final Action
Jan 04, 2018
Final Rejection — §112
Jul 10, 2018
Request for Continued Examination
Jul 16, 2018
Response after Non-Final Action
Sep 05, 2018
Final Rejection — §112
Feb 06, 2019
Request for Continued Examination
Feb 07, 2019
Response after Non-Final Action
Mar 29, 2019
Final Rejection — §112
Jul 02, 2019
Response after Non-Final Action
Oct 01, 2019
Response after Non-Final Action
Oct 01, 2019
Request for Continued Examination
Oct 04, 2019
Response after Non-Final Action
Nov 13, 2019
Non-Final Rejection — §112
May 15, 2020
Response Filed
May 15, 2020
Response after Non-Final Action
Jul 15, 2020
Final Rejection — §112
Jul 16, 2020
Response after Non-Final Action
Oct 04, 2020
Response after Non-Final Action
Oct 22, 2020
Request for Continued Examination
Oct 26, 2020
Response after Non-Final Action
Oct 29, 2020
Final Rejection — §112
Apr 04, 2021
Request for Continued Examination
Apr 05, 2021
Response after Non-Final Action
Aug 16, 2021
Final Rejection — §112
Aug 24, 2021
Response after Non-Final Action
Sep 22, 2021
Response after Non-Final Action
Oct 07, 2021
Response after Non-Final Action
Oct 18, 2021
Response after Non-Final Action
Nov 10, 2021
Response after Non-Final Action
Dec 19, 2021
Request for Continued Examination
Dec 20, 2021
Response after Non-Final Action
Jul 07, 2022
Final Rejection — §112
Oct 19, 2022
Request for Continued Examination
Oct 23, 2022
Response after Non-Final Action
Dec 12, 2022
Final Rejection — §112
Dec 16, 2022
Response after Non-Final Action
Feb 28, 2023
Request for Continued Examination
Mar 04, 2023
Response after Non-Final Action
Mar 27, 2023
Final Rejection — §112
Apr 06, 2023
Response after Non-Final Action
Apr 11, 2023
Applicant Interview (Telephonic)
Apr 13, 2023
Examiner Interview Summary
May 11, 2023
Response after Non-Final Action
Jun 30, 2023
Request for Continued Examination
Jul 10, 2023
Response after Non-Final Action
Oct 31, 2023
Final Rejection — §112
Feb 01, 2024
Response after Non-Final Action
Apr 16, 2024
Request for Continued Examination
Apr 22, 2024
Response after Non-Final Action
Aug 06, 2024
Final Rejection — §112
Dec 01, 2024
Request for Continued Examination
Dec 03, 2024
Response after Non-Final Action
May 22, 2025
Final Rejection — §112
Oct 23, 2025
Request for Continued Examination
Oct 24, 2025
Response after Non-Final Action
Mar 25, 2026
Final Rejection — §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

18-19
Expected OA Rounds
54%
Grant Probability
80%
With Interview (+25.7%)
3y 0m
Median Time to Grant
High
PTA Risk
Based on 1058 resolved cases by this examiner. Grant probability derived from career allow rate.

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