Prosecution Insights
Last updated: April 19, 2026
Application No. 16/831,264

METHOD AND SYSTEM TO ASSESS DISEASE USING DYNAMICAL ANALYSIS OF BIOPHYSICAL SIGNALS

Final Rejection §101
Filed
Mar 26, 2020
Examiner
SHAH, JAY B
Art Unit
3791
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Analytics For Life Inc.
OA Round
4 (Final)
56%
Grant Probability
Moderate
5-6
OA Rounds
3y 6m
To Grant
64%
With Interview

Examiner Intelligence

Grants 56% of resolved cases
56%
Career Allow Rate
206 granted / 367 resolved
-13.9% vs TC avg
Moderate +8% lift
Without
With
+7.6%
Interview Lift
resolved cases with interview
Typical timeline
3y 6m
Avg Prosecution
37 currently pending
Career history
404
Total Applications
across all art units

Statute-Specific Performance

§101
17.8%
-22.2% vs TC avg
§103
34.7%
-5.3% vs TC avg
§102
12.9%
-27.1% vs TC avg
§112
28.2%
-11.8% vs TC avg
Black line = Tech Center average estimate • Based on career data from 367 resolved cases

Office Action

§101
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Status of Claims The amendment filed 9/4/25 is acknowledged. Claims 1-19, 22, 41, 43-44 are pending. Claim 20, 21, 23-40, 42 are canceled. Claim 1, 3, 13, 18, 22, 43 are amended. Claims 2, 4-12, 15-17, 19 are withdrawn from consideration. Claim Rejections - 35 USC § 101 35 U.S.C. 101 reads as follows: Whoever invents or discovers any new and useful process, machine, manufacture, or composition of matter, or any new and useful improvement thereof, may obtain a patent therefor, subject to the conditions and requirements of this title. Claims 1, 3, 13, 14, 18, 21-22, 41-43 are rejected under 35 U.S.C. 101 because the claimed invention is directed to an abstract idea without significantly more. The claim(s) recite(s) determining, by the one or more processors, one or more dynamical properties and a Poincare Map of the biophysical signal data set; and determining, by the one or more processors, an alpha shape object of the Poincare map; determining, by the one or more processors, one or more geometric properties of the alpha shape object; determining, by the one or more processors, one or more estimated values for the presence, non-presence, localization, and/or severity of a disease or condition based on the determined one or more dynamical properties and the one or more determined geometric properties of the alpha shape object, wherein the plurality of geometric properties includes at least one property selected from the group consisting of: a density value of the alpha shape object, a convex surface area value of the alpha shape object, a perimeter value of the alpha shape object, a porosity value of the alpha shape object, and a void area value of the alpha shape object. The abstract idea is part of the Mathematical Concepts group(s) identified in the Ninth Edition, Revision 10.2019 (revised June 2020) of the Manual of Patent Examination Procedure (MPEP). This judicial exception is not integrated into a practical application because they amount to simply implementing the abstract idea on a computer; data-gathering steps do not add a meaningful limitation to the method as they are insignificant extra-solution activity; there is no improvement to a computer or other technology; does not apply the abstract idea to effect a particular treatment or prophylaxis for a disease or medical condition; does not apply the abstract idea with, or by use of, a particular machine. The additional elements are identified as follows: surface sensors and a processor (claim 1) and display (claim 18). The claim(s) does/do not include additional elements that are sufficient to amount to significantly more than the judicial exception because the additional elements, when considered both individually and as a whole, do not amount to significantly more than the abstract idea. The additional computer and data-gathering elements, which are recited at a high level of generality, provide conventional computer and data-gathering functions that do not add meaningful limitations to practicing the abstract idea. Those in the relevant field of art would recognize the above-identified additional elements as being well-understood, routine, and conventional means for data-gathering and computing, as demonstrated by non-patent literature of record in the application (Galiatsatos et al. Usefulness of a Noninvasive Device to Identify Elevated Left Ventricular Filling Pressure Using Finger Photoplethysmography During a Valsalva Maneuver; 2017 – cited by Applicant). Thus, the claimed additional elements “are so well-known that they do not need to be described in detail in a patent application to satisfy 35 U.S.C. § 112(a).” Berkheimer Memorandum, III. A. 3. When considered in combination, the additional elements (generic computer functions and conventional equipment/steps) do not amount to significantly more than the abstract idea. The Federal Circuit has held that combining additional elements for data-gathering with abstract ideas does not make a claim patent-eligible. Looking at the claim limitations as a whole adds nothing that is not already present when looking at the elements taken individually. There is no indication that the combination of elements improves the functioning of a computer or improves any other technology. Their collective functions merely provide conventional computer implementation. Regarding the dependent claims, the dependent claims are directed to either 1) steps that are also abstract or 2) additional data gathering that is well-understood, routine and previously known to the industry. Although the dependent claims are further limiting, they do not recite significantly more than the abstract idea. A narrow abstract idea is still an abstract idea and an abstract idea with additional well-known data-gathering equipment/functions is not significantly more than the abstract idea. Response to Amendment Regarding 101 Rejections, Applicant argues the claims should be found eligible at Step 2A Prong 2. Examiner respectfully disagrees. Applicant refers to Thales, Examiner notes that Thales recited inertial sensors used in a non-conventional approach. This is not the case in the instant application. In fact, the claims merely amount to collecting data, processing it and displaying the results. Examiner notes that “Gathering and analyzing information using conventional techniques and displaying the result” is not an improvement in technology. MPEP 2015.06(A)(II)(iii). Examiner notes that “It is important to note, the judicial exception alone cannot provide the improvement. The improvement can be provided by one or more additional elements.” MPEP 2106.05(a). The rejection is maintained Applicant further argues that the amended claims now applies or uses a judicial exception to effect a particular treatment or prophylaxis for a disease or medical condition. Examiner respectfully disagrees. First, Examiner notes that the limitation “wherein the one or more estimated values are used in a diagnosis of the disease state or condition or to direct treatment of the disease state or condition” does not positively recite any particular treatment. Per MPEP 2106.04(d)(2) “The treatment or prophylaxis limitation must be "particular," i.e., specifically identified so that it does not encompass all applications of the judicial exception(s)”. Further, Examiner notes that any claimed treatment is “optional” and not required in the claimed invention. Applicant further argues that Claim 1 does not recite any of "mathematical relationships, mathematical formulas or equations, and mathematical calculations". Examiner respectfully disagrees. Determining dynamic properties, Poincare maps, and geometrical properties are mathematical relationships. The rejection stands. Conclusion Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to JAY B SHAH whose telephone number is (571)272-0686. The examiner can normally be reached M-F 8-5. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Jennifer Robertson can be reached at 571-272-5001. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. JAY SHAH Primary Examiner Art Unit 3791 /JAY B SHAH/Primary Examiner, Art Unit 3791
Read full office action

Prosecution Timeline

Mar 26, 2020
Application Filed
Apr 20, 2024
Non-Final Rejection — §101
Aug 21, 2024
Response Filed
Nov 15, 2024
Final Rejection — §101
Dec 05, 2024
Interview Requested
Mar 20, 2025
Request for Continued Examination
Mar 24, 2025
Response after Non-Final Action
Apr 01, 2025
Non-Final Rejection — §101
May 27, 2025
Applicant Interview (Telephonic)
May 27, 2025
Examiner Interview Summary
Sep 04, 2025
Response Filed
Dec 12, 2025
Final Rejection — §101 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

5-6
Expected OA Rounds
56%
Grant Probability
64%
With Interview (+7.6%)
3y 6m
Median Time to Grant
High
PTA Risk
Based on 367 resolved cases by this examiner. Grant probability derived from career allow rate.

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