Office Action Predictor
Last updated: April 17, 2026
Application No. 17/054,270

EXHALATION-BASED LUNG CANCER DIAGNOSIS METHOD AND SYSTEM

Final Rejection §112§DP
Filed
Nov 10, 2020
Examiner
VANNI, GEORGE STEVEN
Art Unit
1686
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Exopert Corporation
OA Round
3 (Final)
66%
Grant Probability
Favorable
4-5
OA Rounds
4y 1m
To Grant
92%
With Interview

Examiner Intelligence

Grants 66% — above average
66%
Career Allow Rate
386 granted / 581 resolved
+6.4% vs TC avg
Strong +25% interview lift
Without
With
+25.1%
Interview Lift
resolved cases with interview
Typical timeline
4y 1m
Avg Prosecution
42 currently pending
Career history
623
Total Applications
across all art units

Statute-Specific Performance

§101
26.2%
-13.8% vs TC avg
§103
25.5%
-14.5% vs TC avg
§102
6.7%
-33.3% vs TC avg
§112
13.9%
-26.1% vs TC avg
Black line = Tech Center average estimate • Based on career data from 581 resolved cases

Office Action

§112 §DP
DETAILED ACTION This application is being examined under AIA first-to-file provisions. Continued examination under 37 CFR 1.114 A request for continued examination under 37 CFR 1.114, including the fee set forth in 37 CFR 1.17(e), was filed in this application after final rejection. Since this application is eligible for continued examination under 37 CFR 1.114, and the fee set forth in 37 CFR 1.17(e) has been timely paid, the finality of the previous office action has been withdrawn pursuant to 37 CFR 1.114. MPEP 706.07(h) pertains. Status of claims Canceled: 2 and 11 Pending: 1, 3-10 and 12-14 Withdrawn: 7-8 and 14 Examined: 1, 3-6, 9-10 and 12-13 Independent: 1 and 9 Allowable: 1 and 3-6 Rejections applied Abbreviations x 112/b Indefiniteness PHOSITA "a Person Having Ordinary Skill In The Art before the effective filing date of the claimed invention" 112/b "Means for" BRI Broadest Reasonable Interpretation 112/a Enablement, Written description CRM "Computer-Readable Media" and equivalent language 112 Other IDS Information Disclosure Statement 102, 103 JE Judicial Exception 101 JE(s) 112/a 35 USC 112(a) and similarly for 112/b, etc. 101 Other N:N page:line Double Patenting MM/DD/YYYY date format Priority As detailed on the 5/5/2021 filing receipt, this application claims priority to as early as 5/18/2018. Withdrawal / revision of objections and/or rejections In view of the amendment and remarks: The objections to the claims are withdrawn. The 112/b rejections are withdrawn, except as noted below, and new rejections are applied. Rejections and/or objections not maintained from previous office actions are withdrawn. The following rejections and/or objections are either maintained or newly applied. They constitute the complete set applied to the instant application. Claim rejections - 112/b The following is a quotation of 35 USC 112(b): (b) CONCLUSION. The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. Claims 9-10 and 12-13 are rejected under 112/b, as indefinite for failing to particularly point out and distinctly claim the subject matter which applicant regards as the invention. Claims depending from rejected claims are rejected similarly, unless otherwise noted, and any amendments in response to the following rejections should be applied throughout the claims, as appropriate. With regard to any suggested amendment below, for claim interpretation during the present examination it is assumed that each amendment suggested here is made. However equivalent amendments also would be acceptable. The following issues cause the respective claims to be rejected under 112/b as indefinite: Claim Recitation Comment (suggestions in bold) 9 ...wherein the deep learning processor identifies signal patterns by using sparse coefficients Claim 9 is rejected as directly reciting a machine and a process in the same claim. A claim to a machine, e.g. here a "system," cannot directly recite a process step such as "identifies... using..." For software-embodied process steps (e.g. calculations), this rejection might be overcome by, for example, reciting a data storage device, comprised by the "system," and instructions stored therein and configured according to the recited elements and steps, however support should be identified for any such amendment. It would be insufficient to only add "configured to" because it still would be unclear what structure is required to be configured. Regarding any software-embodied steps, it should be clear whether such steps are in fact software-embodied, and it should be clear whether such software is comprised by the claimed machine or manufacture. 10 ...is supplied... and irradiated... using... Similarly, claim 10 is rejected as directly reciting a machine and a process in the same claim. A claim to a machine, e.g. here a "system," cannot directly recite process steps such as "...is supplied... and irradiated... using..." For physical process steps relying on well-known physical structure, it may suffice to add "configured to" before the process step so as properly focus on claimed structure. 12 ...is obtained..., after collecting... and injecting..., waiting... and then separating... Similarly, claim 12 is rejected as directly reciting a machine and a process in the same claim. A claim to a machine, e.g. here a "system," cannot directly recite process steps such as "...is obtained by, after collecting... and injecting..., waiting... and then separating..." 13 ...processor acquires and stores... using... Similarly, claim 13 is rejected as directly reciting a machine and a process in the same claim. A claim to a machine, e.g. here a "system," cannot directly recite process steps such as "...processor acquires and stores... using..." 9 deep learning processor configured to acquire and store... and configured to acquire and output... Claim 9 is to a 101 machine or manufacture, i.e. a "system" in this instance, limited according to its claimed physical structure, but it is not clear what is the structure associated with the recited "configured to acquire and store..." and "acquire and output..." The recited "system" and "deep learning processor" are not interpreted as requiring structure clearly linking the "system" to the recited steps in a structural sense appropriate to a claim to a machine or manufacture. This rejection might be overcome by, for example, reciting a data storage device, comprised by the "system," and instructions stored therein and configured according to the recited elements and steps, if support for such an amendment can be identified. MPEP 2173.05(p).II pertains regarding a claim directed to both product and process. 9 lung cancer detector and analyzer configured to detect... and configured to confirm... Similarly, claim 9 is to a 101 machine or manufacture, i.e. a "system" in this instance, limited according to its claimed physical structure, but it is not clear what is the structure associated with the recited "configured to detect..." and "confirm..." The recited "system" and "lung cancer detector and analyzer" are not interpreted as requiring structure clearly linking the "system" to the recited steps in a structural sense appropriate to a claim to a machine or manufacture. This rejection might be overcome by, for example, reciting a data storage device, comprised by the "system," and instructions stored therein and configured according to the recited elements and steps, if support for such an amendment can be identified. MPEP 2173.05(p).II pertains regarding a claim directed to both product and process. Claim interpretations The following claim interpretations apply to all instances of the following terms throughout all claims: Claim Recitation Comment 9 deep learning processor Recites means (or an equivalent, nonce term, here "processor") and function and/or result (here "deep learning"), but the recitation does not invoke 112/f because the claim is interpreted as reciting sufficient structure (in this instance in the form of subsequent algorithmic steps) not to invoke. MPEP 2181.I.C pertains. 9 lung cancer detector and analyzer Recites means (or an equivalent, nonce term, here "detector and analyzer") and function and/or result (here "lung cancer detector and analyzer"), but the recitation does not invoke 112/f because the claim is interpreted as reciting sufficient structure (in this instance in the form of subsequent algorithmic steps) not to invoke. MPEP 2181.I.C pertains. No prior art has been applied to the following claims No prior art is applied to claims 1, 3-6, 9-10 and 12-13. Close art, for example as cited in the now withdrawn art rejections, as well as art found in the search histories and on the IDSs, does not teach the instant combination of particularly recited sample presentation, Raman spectroscopy, learning and cell type, and it is not clear that any combinable art of record would have rendered the claims obvious. 101 -- no rejections -- patent eligibility Referring to 101 JE analysis as organized in MPEP 2106, no rejection applies to claims 1, 3-6, 9-10 and 12-13, at least by analogy to analysis Step 2B relating to a non-conventional combination of additional elements causing the claim to read on significantly more than any recited JE (MPEP 2106.05(d)), the combination in this instance comprising at least the particularly recited substrate, Raman spectroscopy, and cell type. In this regard, Applicant's 3/27/2026 remarks at pp. 14-15 also support withdrawal of the rejection. Conclusion No claim is allowed. A shortened statutory period for reply is set to expire THREE MONTHS from the mailing date of this communication. Inquiries Information regarding the filing, management and status of patent applications which are published (available to all users) or unpublished (available to registered users) may be obtained from the Patent Center: https://patentcenter.uspto.gov. Further information is available at https://www.uspto.gov/patents/apply/patent-center, and information about filing in DOCX format is available at https://www.uspto.gov/patents/docx. The Electronic Business Center (EBC) at 866-217-9197 (toll-free) is available for additional questions, and assistance from a Customer Service Representative is available at 800-786-9199 (IN USA OR CANADA) or 571-272-1000. The examiner for this Office action, G. Steven Vanni, may be contacted at: (571) 272-3855 Tu-F 8-7 (ET). If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Larry D. Riggs, II, may be reached at (571) 270-3062. /G. STEVEN VANNI/Primary patents examiner, Art Unit 1686
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Prosecution Timeline

Nov 10, 2020
Application Filed
Sep 03, 2025
Non-Final Rejection — §112, §DP
Dec 08, 2025
Response Filed
Jan 10, 2026
Final Rejection — §112, §DP
Mar 25, 2026
Applicant Interview (Telephonic)
Mar 25, 2026
Examiner Interview Summary
Mar 27, 2026
Request for Continued Examination
Mar 30, 2026
Response after Non-Final Action
Apr 04, 2026
Non-Final Rejection — §112, §DP (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

4-5
Expected OA Rounds
66%
Grant Probability
92%
With Interview (+25.1%)
4y 1m
Median Time to Grant
High
PTA Risk
Based on 581 resolved cases by this examiner. Grant probability derived from career allow rate.

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