DETAILED ACTION
Notice of Pre-AIA or AIA Status
The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA .
Claim Rejections - 35 USC § 103
The text of those sections of Title 35, U.S. Code not included in this action can be found in a prior Office action.
Claims 21-26, 29, 32-39 is/are rejected under 35 U.S.C. 103 as being unpatentable over Shapiro et al (WO 2015/042101, of record, reference below is to the US patent publication of the WO document, US 2017/0121708, also of record) in view of Kim et al (Sci Rep. 2015, of record).
Claims 21-26, 29-39 is/are rejected under 35 U.S.C. 103 as being unpatentable over Shapiro et al (WO 2015/042101, of record) in view of Kim et al (Sci Rep. 2015 of record) and Stephan et al (US PGPUB 2016/0145348, of record).
These rejections are maintained for reasons made of record and for reasons set forth below.
Response to Arguments
Applicant's arguments filed 9/29/2025 have been fully considered but they are not persuasive. Applicants essentially assert that Shapiro et al is directed to RNA-DNA hybrids, not DNA nanoparticles as in the instant claims. Such is not convincing. The instant claims only require “DNA”, and do not remove RNA/DNA hybrids from the claimed scope
Any inquiry concerning this communication or earlier communications from the examiner should be directed to Michael Burkhart whose telephone number is (571)272-2915. The examiner can normally be reached M-F 8-5.
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If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Tracy Vivlemore can be reached at 571 272-2914. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300.
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Michael Burkhart
Examiner
Art Unit 1633
/MICHAEL D BURKHART/Primary Examiner, Art Unit 1638