Prosecution Insights
Last updated: October 25, 2026
Application No. 17/266,592

Homologous Recombination Reporter Construct and Uses Thereof

Final Rejection
Filed
Feb 06, 2021
Priority
Aug 06, 2018 — provisional 62/715,117 +2 more
Examiner
SMALL, KATHERINE R
Art Unit
1633
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Nemametrix Inc.
OA Round
4 (Final)
69%
Grant Probability
Favorable
5-6
OA Rounds
0m
Est. Remaining
99%
With Interview

Examiner Intelligence

Grants 69% — above average
69%
Career Allowance Rate
43 granted / 62 resolved
+9.4% vs TC avg
Strong +30% interview lift
Without
With
+29.6%
Interview Lift
resolved cases with interview
Typical timeline
3y 10m
Avg Prosecution
21 currently pending
Career history
81
Total Applications
across all art units

Statute-Specific Performance

§101
5.1%
-34.9% vs TC avg
§103
41.6%
+1.6% vs TC avg
§102
24.0%
-16.0% vs TC avg
§112
27.4%
-12.6% vs TC avg
Black line = Tech Center average estimate • Based on career data from 62 resolved cases

Prosecution Timeline

Show 3 earlier events
Jul 19, 2024
Final Rejection mailed
Sep 13, 2024
Interview Requested
Jan 20, 2025
Notice of Allowance
Aug 20, 2025
Request for Continued Examination
Aug 22, 2025
Response after Non-Final Action
Jan 22, 2026
Non-Final Rejection mailed
Mar 12, 2026
Response Filed
Apr 29, 2026
Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12760287
CONSTRUCTS FOR IMPROVED HDR-DEPENDENT GENOMIC EDITING
5y 5m to grant Granted Oct 13, 2026
Patent 12729384
A METHOD TO TREAT DISEASE USING A NUCLEIC ACID VECTOR ENCODING A HIGHLY COMPACT MULTI-INPUT LOGIC GATE
5y 5m to grant Granted Sep 08, 2026
Patent 12714727
PHARMACEUTICAL COMPOSITION FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS
4y 11m to grant Granted Aug 25, 2026
Patent 12642256
HEMOPHILIA B RAT MODEL
4y 8m to grant Granted Jun 02, 2026
Patent 12630821
Selective Curbing of Unwanted RNA Editing (SECURE) DNA Base Editor Variants
5y 1m to grant Granted May 19, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

5-6
Expected OA Rounds
69%
Grant Probability
99%
With Interview (+29.6%)
3y 10m (~0m remaining)
Median Time to Grant
High
PTA Risk
Based on 62 resolved cases by this examiner. Grant probability derived from career allowance rate.

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