Prosecution Insights
Last updated: July 17, 2026
Application No. 17/414,127

ALICYCLIC MUSK FRAGRANCE COMPOUNDS

Final Rejection §103
Filed
Jun 15, 2021
Priority
Dec 20, 2018 — nonprovisional of PCTEP2018086190
Examiner
YU, HONG
Art Unit
1614
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Symrise AG
OA Round
5 (Final)
31%
Grant Probability
At Risk
6-7
OA Rounds
0m
Est. Remaining
37%
With Interview

Examiner Intelligence

Grants only 31% of cases
31%
Career Allowance Rate
215 granted / 690 resolved
-28.8% vs TC avg
Moderate +6% lift
Without
With
+5.7%
Interview Lift
resolved cases with interview
Typical timeline
3y 7m
Avg Prosecution
62 currently pending
Career history
763
Total Applications
across all art units

Statute-Specific Performance

§101
0.2%
-39.8% vs TC avg
§103
78.6%
+38.6% vs TC avg
§102
7.0%
-33.0% vs TC avg
§112
3.8%
-36.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 690 resolved cases

Office Action

§103
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. DETAILED ACTION Status of claims The amendment filed on 05/11/2026 is acknowledged. Claims 1-11, 13-16, 18-20, 22, 23, 27, 29, 30, 32, 34, and 38 have been canceled and claims 28, 31, 39, and 40 have been withdrawn. Claims 12, 17, 21, 24-26, 33, and 35-37 are under examination in the instant office action. Applicants’ amendments necessitate reconsideration of species election dated 03/22/2024 and a species election requirement among claims 12, 21, 24, 26, 28, and 31. Applicant indicated that compound 2 (2-(1-(3,3-dimethylcyclohexyl)ethoxy)-2-methylpropyl tetrahydrofuran-2-carboxylate) would be elected if a species election is needed. Applicants’ elected species of compound 2 in claims 21 and 28 is free of the prior art. As a result, the search has been extended to non-elected compound 7 in claims 24 and 31 (2-(1-(3,3-dimethylcyclohexyl)ethoxy)-2-oxoethyl 4-oxopentanoate). MPEP 803.02 III: If the examiner determines that the elected species is allowable over the prior art, the examination of the Markush claim will be extended. Claims 12, 17, 24 25, 26, 31, 33, and 35-37 will presently be examined to the extent they read on the elected subject matter of record. Rejections withdrawn Applicant’s amendments and arguments filed on 05/11/2026 are acknowledged and have been fully considered. Any rejection and/or objection not specifically addressed below is herein withdrawn. Applicant’s amendments have overcome the 35 U.S.C. 102(a)(1) rejection of claims 12, 17, 19, and 25-27 over McGee et al. (US 2010/0034766 A1) and 35 U.S.C. 103(a) rejections of claims 12, 17, 19, 22, 23, 25-27, 29, 30, 33, and 35 over McGee et al. (US 2010/0034766 A1) and of claims 12, 17, 19, 22, 23, 25-27, 29, 30, 33, and 35-37 over Williams (US 6,384,269 B1) from the previous Office Action. The following rejections and/or objections are either reiterated or newly applied. They constitute the complete set of rejections and/or objections presently being applied to the instant application. New ground of rejections necessitated by Applicant’s amendment The amendments necessitate the following new ground of rejection. Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. This application currently names joint inventors. In considering patentability of the claims under 35 U.S.C. 103(a), the examiner presumes that the subject matter of the various claims was commonly owned at the time any inventions covered therein were made absent any evidence to the contrary. Applicant is advised of the obligation under 37 CFR 1.56 to point out the inventor and invention dates of each claim that was not commonly owned at the time a later invention was made in order for the examiner to consider the applicability of 35 U.S.C. 103(c) and potential 35 U.S.C. 102(e), (f) or (g) prior art under 35 U.S.C. 103(a). The factual inquiries set forth in Graham v. John Deere Co., 383 U.S. 1, 148 USPQ 459 (1966), that are applied for establishing a background for determining obviousness under 35 U.S.C. 103(a) are summarized as follows: 1. Determining the scope and contents of the prior art. 2. Ascertaining the differences between the prior art and the claims at issue. 3. Resolving the level of ordinary skill in the pertinent art. 4. Considering objective evidence present in the application indicating obviousness or nonobviousness. Claims 12, 17, 24-26, 31, 33, and 35-37 are rejected under 35 U.S.C. 103(a) as being unpatentable over Hölscher (US 2013/0261036 A1). Hölscher teaches a method of imparting or intensifying particular musk and fruity notes to a product (the instant claims 12, 17, 26) comprising incorporating, into the article (abstract and paragraph 19, 61-66, 81-85, 90-96, and 111, and claims 5 and 13), a perfume of formula PNG media_image1.png 200 400 media_image1.png Greyscale with ------ being saturated or unsaturated, R1 = H, X = O, n=1, R2 being (iv) a CH2-carbonyl-O-R3 group, wherein R3 = a straight, branched or cyclic and saturated or unsaturated C1-4 alkyl group, i.e., incluidng methyl → 2-(1-(3,3-dimethylcyclohexyl)ethoxy)-2-oxoethyl 3-oxobutanoate) (abstract and claim 1) in admixture with further perfumes with a perfume to further perfume mass ratio of 1:25-100 (the instant claim 25, 33, and 35) (paragraph 67, 68). Hölscher does not teach esters of aliphatic carboxylic acids, esters of cyclic alcohols, esters of cycloaliphatic alcohols, and esters of cycloaliphatic carboxylic acids being must have further perfumes (the instant claims 36 and 37). Hölscher teaches does not teach the same perfume (2-(1-(3,3-dimethylcyclohexyl)ethoxy)-2-oxoethyl 3-oxobutanoate vs the claimed 2-(1-(3,3-dimethylcyclohexyl)ethoxy)-2-oxoethyl 4-oxopentanoate, compound 7) in the instant claims 12, 24, 26, and 31. This deficiency is cured by the rationale that when chemical compounds have “very close” structural similarities and similar utilities, without more a prima facie case may be made. In the instant case, the difference between the claimed compound 7 and the compound taught by Hölscher is the claimed 4-oxopentanoate vs 3-oxobutanoate taught by Hölscher, i.e., R2 being CH2-carbonyl-O-CH3 vs R2 being CH2-CH2-carbonyl-O-CH3. Please refer to MPEP 2144.09 II.: Compounds which are position isomers (compounds having the same radicals in physically different positions on the same nucleus) or homologs (compounds differing regularly by the successive addition of the same chemical group, e.g., by -CH2- groups) are generally of sufficiently close structural similarity that there is a presumed expectation that such compounds possess similar properties. Response to Applicants’ arguments: Applicant’s arguments, filed on 05/11/2026, have been fully considered but they are moot in view of new ground of rejections. Conclusion No claims are allowed. Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any extension fee pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to HONG YU whose telephone number is (571)270-1328. The examiner can normally be reached on 9 am - 5:30 pm. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Ali Soroush can be reached on 571-272-9925. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of an application may be obtained from the Patent Application Information Retrieval (PAIR) system. Status information for published applications may be obtained from either Private PAIR or Public PAIR. Status information for unpublished applications is available through Private PAIR only. For more information about the PAIR system, see http://pair-direct.uspto.gov. Should you have questions on access to the Private PAIR system, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative or access to the automated information system, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /HONG YU/ Primary Examiner, Art Unit 1614
Read full office action

Prosecution Timeline

Show 2 earlier events
Jan 04, 2025
Response Filed
Mar 17, 2025
Final Rejection mailed — §103
Sep 17, 2025
Request for Continued Examination
Sep 18, 2025
Response after Non-Final Action
Nov 12, 2025
Non-Final Rejection mailed — §103
Feb 09, 2026
Non-Final Rejection mailed — §103
May 11, 2026
Response Filed
Jul 07, 2026
Final Rejection mailed — §103 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12653185
MICROCAPSULES ENCAPSULATING LAMBDA-CYHALOTHRIN
7y 5m to grant Granted Jun 16, 2026
Patent 12648896
EMULSION COSMETIC
5y 4m to grant Granted Jun 09, 2026
Patent 12638273
SKIN MARKING SOLUTION AND METHOD OF USE
7y 1m to grant Granted May 26, 2026
Patent 12622852
COMPOSITIONS AND METHODS FOR STYLING HAIR
3y 10m to grant Granted May 12, 2026
Patent 12611424
COSMETIC/DERMATOLOGICAL COMPOSITION
4y 9m to grant Granted Apr 28, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.
Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

6-7
Expected OA Rounds
31%
Grant Probability
37%
With Interview (+5.7%)
3y 7m (~0m remaining)
Median Time to Grant
High
PTA Risk
Based on 690 resolved cases by this examiner. Grant probability derived from career allowance rate.

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month