Prosecution Insights
Last updated: April 19, 2026
Application No. 17/419,442

LIQUID NICOTINE FORMULATION

Non-Final OA §103
Filed
Jun 29, 2021
Examiner
TUCKER, PHILIP C
Art Unit
1745
Tech Center
1700 — Chemical & Materials Engineering
Assignee
Philip Morris Products, S.A.
OA Round
5 (Non-Final)
23%
Grant Probability
At Risk
5-6
OA Rounds
3y 11m
To Grant
38%
With Interview

Examiner Intelligence

Grants only 23% of cases
23%
Career Allow Rate
14 granted / 60 resolved
-41.7% vs TC avg
Moderate +14% lift
Without
With
+14.3%
Interview Lift
resolved cases with interview
Typical timeline
3y 11m
Avg Prosecution
12 currently pending
Career history
72
Total Applications
across all art units

Statute-Specific Performance

§103
50.6%
+10.6% vs TC avg
§102
22.6%
-17.4% vs TC avg
§112
22.4%
-17.6% vs TC avg
Black line = Tech Center average estimate • Based on career data from 60 resolved cases

Office Action

§103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Response to Amendment Acknowledgement is made of the Request for Continued Examination of 1/29/2026. Applicant’s amendment has overcome the rejection over Bowen, however the rejection over Bruton is maintained. Claim Rejections - 35 USC § 103 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. Claim(s) 16, 17, 25-27, 30, 31 and 33-34 are rejected under 35 U.S.C. 103 as being unpatentable over Bruton (US 12,232,522). Bruton teaches a system for producing a nicotine aerosol for use in e-cigarettes (column 1, lines 16-20). Regarding claims 16, 17 and 34, Bruton does not teach the presence of caffeine and teaches a nicotine content of greater than 1%, thus over lapping in scope with the claimed Less than or equal to about 3% (column 7, lines 60-64 and also claim 7, no greater than 2%, see also column 10). Bruton teaches that water can be present in the formulation at a level of up to 50% (column 6, lines 54-61), and that the formulation may comprise polyhydric alcohols carriers such as propylene glycol and glycerol (column 5, lines 55-62). The amount of carrier can be as low as 10% (column 6, line 1), thus rendering obvious that the ratio of water to the polyhydric alcohols may be greater than 2 or 3. Bruton teaches that the combined amount of water and carrier may be as high as 90% (column 7,lines 35-37), thus rendering the claimed greater than or equal to about 85% obvious to one of ordinary skill in the art. Since the water content can be as high as 50%, and the polyhydric alcohol content can be as low as 10%, such would give a ratio of 5, which is within the less than 8 taught in claim 17. Bruton differs in teaching the amount of organic acid in an electrolyte used instead of the total formulation. Bruton however teaches that the organic acid may be present in any amount to provide carbon dioxide upon electrolysis (column 13, lines37-37), see also claim 9 which indicates that the nicotine formulation contains the carbon dioxide source.. It would be obvious to one of ordinary skill in the art to vary the amount of the organic acid in the formulation, including the levels of about 2% or greater, in order to achieve providing sufficient carbon dioxide from electrolysis. With respect to claims 25-27, 30 and 31, Bruton teaches cartridges and heaters used in the invention for e-cigarettes (column19, lines 11-34). With respect to claim 33, Bruton teaches that the carrier can be a mixture of glycerol and propylene glycol (column 5, lines 61-62) and may be present in a level of 20% to 98% (column 6, line 2), thus over lapping and rendering obvious the greater than or equal to 20% claimed. Claim(s) 22, 23, 28 and 29 are rejected under 35 U.S.C. 103 as being unpatentable over Bruton (US 12,232,522) as applied to claims 16, 25 and 26 above in view of Cameron (US 2017/0325494). With respect to claim 22, Bruton teaches the use of water insoluble flavorants such as Rose oil and Orange oil (column 6, lines 30-51). Bruton fails to teach that the flavorant is present in an amount greater or equal to 2%. In the same field of endeavor, Cameron discloses a liquid nicotine composition comprising a flavoring agent which can comprise Rose oil or Orange Oil (0078) Cameron further teaches that the liquid nicotine composition comprises about 0.01 weight percent to about 10 weight percent of the flavoring agent ([0086]). Therefore it would have been obvious to one of ordinary skill in the art to utilize the Rose oil or Orange oil of Bruton at a level of up to 10% (greater than 2%), since such levels would be expected to have the result of giving an effective flavor to the nicotine composition of Bruton. Regarding claim 23, Cameron discloses the liquid nicotine composition comprises alpha-methylbenzyl alcohol (C8H10O) as a flavorant ([0078]). As is known in the art, alpha-methylbenzyl alcohol (i.e., partially water-soluble solvent) has a water solubility value of about 19.54 mg/ml at 25oC at room temperature (i.e., 20oC-25oC). It would have been obvious to one of ordinary skill in the art before the effective filing date of the claimed invention to have modified the liquid nicotine formulation (i.e., pre-vaporization formulation) of Bruton to incorporate the teachings of Cameron by including alpha-methylbenzyl alcohol into the inhalable nicotine composition, so that the formulation of Bruton would have a desirable fragrance, as recognized by Cameron. Regarding claims 28-29, Cameron discloses an electronic vaporizing device comprising a piezoelectric dispersing element (i.e., non-thermal atomizer) which causes dispersion (i.e., vaporize) of the vaporizable material (i.e., liquid nicotine composition) by producing ultrasonic vibrations ([0098]). Cameron is considered to be analogous art because it is reasonably pertinent to the aerosol-generating devices. It would have been obvious to one of ordinary skill in the art before the effective filing date of the claimed invention to have modified the electronic vaping device of Bruton to incorporate the teachings of Cameron by including a piezoelectric dispersing element to vaporize the liquid nicotine composition without the need for a heating element, as recognized by Cameron. Response to Arguments Applicant’s amendment has overcome the rejection over Bowen, since oxalic acid does not have the required water solubility of claim 16. Applicant’s arguments with regard to Bruton have been considered but are not deemed persuasive. Applicant has argued that providing the organic acid in the nicotine formulation would protonate the nicotine rather than providing carbon dioxide upon electrolysis. This assertion helps to affirm the rejection rather than traverse it, since one of ordinary skill would provide sufficient organic acid to both protonate the nicotine and still be able to produce the carbon dioxide. Clearly when greater than 2% of the acid is needed to protonate the nicotine and produce the carbon dioxide, one of ordinary skill would utilize a sufficient amount of the organic acid to enable the invention to work. Applicant’s arguments regarding Example I of Bruton is noted, however a reference is not limited to preferred embodiments, but must be evaluated for all that it teaches (see MPEP 2123). Any inquiry concerning this communication or earlier communications from the examiner should be directed to PHILIP C TUCKER whose telephone number is (571)272-1095. The examiner can normally be reached M-F 8-4:30. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Alexa Neckel can be reached at 571-272-2450. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /PHILIP C TUCKER/Supervisory Patent Examiner, Art Unit 1745
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Prosecution Timeline

Jun 29, 2021
Application Filed
Jan 10, 2024
Non-Final Rejection — §103
Apr 25, 2024
Response Filed
Jul 23, 2024
Final Rejection — §103
Oct 03, 2024
Examiner Interview Summary
Oct 03, 2024
Applicant Interview (Telephonic)
Nov 05, 2024
Request for Continued Examination
Nov 06, 2024
Response after Non-Final Action
Jan 10, 2025
Non-Final Rejection — §103
Jul 17, 2025
Response Filed
Oct 16, 2025
Final Rejection — §103
Dec 22, 2025
Response after Non-Final Action
Jan 29, 2026
Request for Continued Examination
Jan 31, 2026
Response after Non-Final Action
Feb 05, 2026
Non-Final Rejection — §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

5-6
Expected OA Rounds
23%
Grant Probability
38%
With Interview (+14.3%)
3y 11m
Median Time to Grant
High
PTA Risk
Based on 60 resolved cases by this examiner. Grant probability derived from career allow rate.

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