Prosecution Insights
Last updated: April 19, 2026
Application No. 17/597,646

ACTIVE AGENT FOR USE IN HAIR GROWTH REGULATION

Non-Final OA §102§103
Filed
Jan 14, 2022
Examiner
LIU, TRACY
Art Unit
1614
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Cutaneon - Skin & Hair Innovations GmbH
OA Round
6 (Non-Final)
55%
Grant Probability
Moderate
6-7
OA Rounds
3y 3m
To Grant
83%
With Interview

Examiner Intelligence

Grants 55% of resolved cases
55%
Career Allow Rate
363 granted / 657 resolved
-4.7% vs TC avg
Strong +28% interview lift
Without
With
+27.5%
Interview Lift
resolved cases with interview
Typical timeline
3y 3m
Avg Prosecution
99 currently pending
Career history
756
Total Applications
across all art units

Statute-Specific Performance

§101
1.0%
-39.0% vs TC avg
§103
50.2%
+10.2% vs TC avg
§102
6.3%
-33.7% vs TC avg
§112
23.2%
-16.8% vs TC avg
Black line = Tech Center average estimate • Based on career data from 657 resolved cases

Office Action

§102 §103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claims included in the prosecution are claims 1, 8-13 and 16-20. Applicants' arguments, filed 01/23/2026, have been fully considered. Rejections and/or objections not reiterated from previous office actions are hereby withdrawn. The following rejections and/or objections are either reiterated or newly applied. They constitute the complete set presently being applied to the instant application. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claims 1, 8-13 and 16-20 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Oto et al. (JP 2008280308 A, Nov. 20, 2008) (hereinafter Oto). Oto discloses a hair papilla cell growth promoter containing at least one of an extract from tillite, amarogentin, and amarothwellin as an active ingredient, and further contains other ingredients as necessary (page 6 of translation). The other components in the hair papilla cell promoter are not limited as long as the effects of the composition are not impaired. For example, a pharmacologically acceptable carrier may be included (page 7 of translation). Suitable carriers include carboxymethylcellulose (page 8 of translation). The hair papilla cell growth promoter may be used to treat androgenetic alopecia (i.e., nonscarring alopecia) (i.e., a condition that is not caused by a disease or disorder) (page 10 of translation). The hair papilla cell growth promoter may be formulated as a hair lotion (page 14 of translation). Oto anticipates the instant claims insofar as specifically disclosing using amarogentin to treat hair growth. Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. The factual inquiries for establishing a background for determining obviousness under 35 U.S.C. 103 are summarized as follows: 1. Determining the scope and contents of the prior art. 2. Ascertaining the differences between the prior art and the claims at issue. 3. Resolving the level of ordinary skill in the pertinent art. 4. Considering objective evidence present in the application indicating obviousness or nonobviousness. Claims 1, 8-13 and 16-20 are rejected under 35 U.S.C. 103 as being unpatentable over Oto et al. (JP 2008280308 A, Nov. 20, 2008) (hereinafter Oto). The instant claims are believed to be anticipated by Oto. However, purely arguendo, for the purposes of complete prosecution, and for the purposes of this ground of rejection, Oto will be interpreted as though it does not anticipate the instant claims. Oto discloses a hair papilla cell growth promoter containing at least one of an extract from tillite, amarogentin, and amarothwellin as an active ingredient, and further contains other ingredients as necessary (page 6 of translation). The other components in the hair papilla cell promoter are not limited as long as the effects of the composition are not impaired. For example, a pharmacologically acceptable carrier may be included (page 7 of translation). Suitable carriers include carboxymethylcellulose (page 8 of translation). The hair papilla cell growth promoter may be used to treat androgenetic alopecia (i.e., nonscarring alopecia) (i.e., a condition that is not caused by a disease or disorder) (page 10 of translation). The hair papilla cell growth promoter may be formulated as a hair lotion (page 14 of translation). The prior art discloses a hair papilla cell growth promoter containing amarogentin as an active ingredient (page 6 of translation). This would provide a composition as claimed instantly. The prior art is not anticipatory insofar as one must select amarogentin as the active ingredient in the reference. It would have been obvious, however, to make this combination since all the claimed elements were known in the prior art and one skilled in the art could have combined the elements as claimed by known methods with no change in their respective functions, and the combination yielded nothing more than predictable results to one of ordinary skill in the art. See MPEP 2143(I)(A). Response to Arguments Applicant’s arguments have been considered but are moot because new rejections necessitated by Applicant’s amendment have been made. Conclusion Claims 1, 8-13 and 16-20 are rejected. No claims are allowed. Any inquiry concerning this communication or earlier communications from the examiner should be directed to TRACY LIU whose telephone number is (571)270-5115. The examiner can normally be reached Mon-Fri 9 am - 5 pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Ali Soroush can be reached at 571-272-9925. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /TRACY LIU/Primary Examiner, Art Unit 1614
Read full office action

Prosecution Timeline

Jan 14, 2022
Application Filed
Sep 10, 2024
Non-Final Rejection — §102, §103
Dec 11, 2024
Response Filed
Jan 14, 2025
Non-Final Rejection — §102, §103
Mar 28, 2025
Response Filed
Apr 09, 2025
Final Rejection — §102, §103
May 13, 2025
Response after Non-Final Action
Jul 07, 2025
Request for Continued Examination
Jul 09, 2025
Response after Non-Final Action
Jul 14, 2025
Non-Final Rejection — §102, §103
Oct 14, 2025
Response Filed
Oct 29, 2025
Final Rejection — §102, §103
Dec 23, 2025
Response after Non-Final Action
Jan 23, 2026
Request for Continued Examination
Jan 27, 2026
Response after Non-Final Action
Feb 20, 2026
Non-Final Rejection — §102, §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

6-7
Expected OA Rounds
55%
Grant Probability
83%
With Interview (+27.5%)
3y 3m
Median Time to Grant
High
PTA Risk
Based on 657 resolved cases by this examiner. Grant probability derived from career allow rate.

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