Prosecution Insights
Last updated: April 19, 2026
Application No. 17/622,395

EXTERNAL PREPARATION FOR SKIN

Final Rejection §103
Filed
Dec 23, 2021
Examiner
SOROUSH, LAYLA
Art Unit
1622
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Kao Corporation
OA Round
2 (Final)
40%
Grant Probability
Moderate
3-4
OA Rounds
3y 10m
To Grant
83%
With Interview

Examiner Intelligence

Grants 40% of resolved cases
40%
Career Allow Rate
349 granted / 868 resolved
-19.8% vs TC avg
Strong +43% interview lift
Without
With
+43.0%
Interview Lift
resolved cases with interview
Typical timeline
3y 10m
Avg Prosecution
53 currently pending
Career history
921
Total Applications
across all art units

Statute-Specific Performance

§101
0.6%
-39.4% vs TC avg
§103
50.3%
+10.3% vs TC avg
§102
12.5%
-27.5% vs TC avg
§112
12.9%
-27.1% vs TC avg
Black line = Tech Center average estimate • Based on career data from 868 resolved cases

Office Action

§103
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . DETAILED ACTION Applicant’s response filed on September 19, 2025 to the Final rejection mailed on July 16, 2025 is acknowledged. The claims corresponding to the elected subject matter are 1, 8-14 are herein acted on the merits. Claim 15-16 is withdrawn. Information Disclosure Statement No new information disclosure statement(s) (IDS) filed. Response to Arguments Applicant’s arguments over the 35 U.S.C. 103 rejection of claims 1, 8-14 over Masamichi et al. ( JP2009046472A) in view of Wiechers (Formulating at pH 4-5: How Lower pH Benefits the Skin and Formulations. Oct 28th, 2013) is not persuasive. The rejection is herewith maintained. Applicant argues, Masamichi et al. does not disclose the use of two or more of polyhydric alcohol fatty acid ester-type nonionic surfactants. Applicant points to Table I and states the combination of the two or more polyhydric alcohol fatty acid ester-type nonionic surfactants provides an unexpected improvement in a number of properties. The Examiner’s contention is that ''[I]t is prima facie obvious to combine two compositions each of which is taught by the prior art to be useful for the same purpose, in order to form a third composition to be used for the very same purpose." In re Kerkhoven, 626 F.2d 846, 850, 205 USPQ 1069, 1072 (CCPA 1980.) Moreover, the Examiner points out that while the Applicant argues unexpected improvement in a number of properties, the Examples compare a very specific formulation (components and amounts), while the claims are broad to many different components encompassed by i.e. A, B, C, and D. The arguments do not commensurate in scope with the claims. Furthermore, the Examiner suggests quantifying what the evaluation in Table I corresponds to in terms of unexpected results. For example, what does a letter ‘E’ mean under the evaluation? The arguments are not persuasive. The rejections are as below: Claim Rejections - 35 USC § 103 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. Claims 1, 8-14 are rejected under 35 U.S.C. 103(a) as being unpatentable over Masamichi et al. ( JP2009046472A) in view of Wiechers (Formulating at pH 4-5: How Lower pH Benefits the Skin and Formulations. Oct 28th, 2013) Masamichi et al. teaches an emulsified composition comprising prednisolone acetate valerate, higher alcohols such as cetanol, stearyl alcohol, etc, lecithin preferably 5 to 30% by weight used include soybean lecithin, egg yolk lecithin, purified soybean lecithin, purified egg yolk lecithin, hydrogenated soybean lecithin, egg yolk lysophosphatidylcholine, soybean lysophospholipid and the like; surfactants other than the lecithin include polyoxyethylene monostearate (20) sorbitan (polysorbate 60); moisturizers including extracts from plants such as ceramides. The emulsified composition of the present invention may further contain water. The formulation has an inhibitory effect on Staphylococcus aureus adhesion and an excellent moisturizing effect. It has been found that the emulsified composition is useful for treating, preventing or ameliorating symptoms caused by skin dryness and / or diseases (especially atopic dermatitis etc.) showing symptoms caused by dry skin. While the reference does not exemplify a formulation comprising the specific stearyl alcohol, hydrogenated soybean lecithin, polyoxyethylene monostearate (20) sorbitan, ceramides and water, the reference does teach each component at a pH as claimed. Wiechers teaches formulations for topical application with a pH between 4-5, or 5.5. It would have been obvious to one of ordinary skill in the art at the time of filing to incorporate a stearyl alcohol, hydrogenated soybean lecithin, polyoxyethylene monostearate (20) sorbitan, ceramides and water at a pH of 4-5. The motivation to incorporate stearyl alcohol, hydrogenated soybean lecithin, polyoxyethylene monostearate (20) sorbitan, ceramides and water comes from the teaching in Masamichi et al. that stearyl alcohol acts as a base, hydrogenated soybean lecithin and polyoxyethylene monostearate (20) sorbitan as surfactants, and ceramides as moisturizers and Wiechers teaching of the importance of this acidic pH for normal skin homeostasis. Hence, a skilled artisan would have had reasonable expectation of success in achieving similar efficacy and results. Additionally, since the general conditions of the claim are taught in the prior art, discovering optimum or workable mass% ranges and ratios involves only routine skill in the art (In re Aller). Conclusions No claims are allowed. The arguments are not persuasive and the rejection is made FINAL. Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any extension fee pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Contact Information Any inquiry concerning this communication or earlier communications from the examiner should be directed to LAYLA SOROUSH whose telephone number is (571)272-5008. The examiner can normally be reached on Monday thru Friday; 8:30 AM to 5:00 PM PST. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner's supervisor, James Henry Alstrum-Acevedo, can be reached on (571) 272-5548. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /LAYLA SOROUSH/ Primary Examiner, Art Unit 1622
Read full office action

Prosecution Timeline

Dec 23, 2021
Application Filed
Jul 12, 2025
Non-Final Rejection — §103
Sep 19, 2025
Response Filed
Jan 14, 2026
Final Rejection — §103 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

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TOPICAL FORMULATION FOR A JAK INHIBITOR
2y 5m to grant Granted Mar 03, 2026
Patent 12544343
TREATMENT OF INFLAMMATORY CONDITION IN MUCOUS MEMBRANE OR SKIN
2y 5m to grant Granted Feb 10, 2026
Patent 12544381
TOPICAL FORMULATION FOR JAK INHIBITOR
2y 5m to grant Granted Feb 10, 2026
Patent 12527731
ACRYLATE-FREE COSMETIC EMULSION
2y 5m to grant Granted Jan 20, 2026
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CANCER TREATMENTS TARGETING CANCER STEM CELLS
2y 5m to grant Granted Jan 13, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
40%
Grant Probability
83%
With Interview (+43.0%)
3y 10m
Median Time to Grant
Moderate
PTA Risk
Based on 868 resolved cases by this examiner. Grant probability derived from career allow rate.

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