Last updated: April 19, 2026

Application No. 17/629,654

INHIBITORS OF ANTIBIOTIC RESISTANCE MEDIATED BY ARNT

Final Rejection

Filed

Jan 24, 2022

Examiner

CREWS, JARET JAMES

Art Unit

1691

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Fondazione Istituto Italiano Di Tecnologia

OA Round

2 (Final)

This examiner grants 47% of cases after interview

— +69.8% interview lift. A telephonic interview to clarify the technical implementation could significantly improve the outcome.

Based on 72 resolved cases, 2023–2026

Examiner Intelligence

CREWS, JARET JAMES View full profile →

Grants 47% of resolved cases

Career Allow Rate

34 granted / 72 resolved

-12.8% vs TC avg

Strong +70% interview lift

Without

With

+69.8%

Interview Lift

resolved cases with interview

Typical timeline

3y 1m

Avg Prosecution

67 currently pending

Career history

139

Total Applications

across all art units

Statute-Specific Performance

§101

4.0%

-36.0% vs TC avg

§103

34.3%

-5.7% vs TC avg

§102

18.2%

-21.8% vs TC avg

§112

24.6%

-15.4% vs TC avg

Black line = Tech Center average estimate • Based on career data from 72 resolved cases

Prosecution Timeline

Jan 24, 2022

Application Filed

Mar 04, 2025

Non-Final Rejection

Jun 09, 2025

Response Filed

Sep 03, 2025

Final Rejection (current)

Precedent Cases

Applications granted by this same examiner with similar technology

17/641,294

Patent 12565575

NEW CYCLODEXTRIN DIMERS AND THEIR USES THEREOF AS CHEMICAL SCAVENGERS

2y 5m to grant Granted Mar 03, 2026

17/766,984

Patent 12559512

METHOD FOR PRODUCING GLYCOSIDE COMPOUND

2y 5m to grant Granted Feb 24, 2026

18/813,368

Patent 12534542

COMPOSITIONS OF HYDROXYPROPYL-BETA-CYCLODEXTRIN AND METHODS OF PURIFYING THE SAME

2y 5m to grant Granted Jan 27, 2026

18/958,956

Patent 12509531

COMPOSITIONS OF HYDROXYPROPYL-BETA-CYCLODEXTRIN AND METHODS OF PURIFYING THE SAME

2y 5m to grant Granted Dec 30, 2025

17/525,054

Patent 12478637

METHOD FOR SUPPRESSING INTERVERTEBRAL DISC PAIN

2y 5m to grant Granted Nov 25, 2025

Study what changed to get past this examiner. Based on 5 most recent grants.

AI Strategy Recommendation

Get an AI-powered prosecution strategy using examiner precedents, rejection analysis, and claim mapping.

Prosecution Projections

3-4

Expected OA Rounds

47%

Grant Probability

99%

With Interview (+69.8%)

3y 1m

Median Time to Grant

Moderate

PTA Risk

Based on 72 resolved cases by this examiner. Grant probability derived from career allow rate.