Notice of Pre-AIA or AIA Status
The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claims 1 and 3-6 are pending in this application.
Response to Amendment
2. Applicant’s amendment filed 12/29/2025 in response to the previous Office Action (06/30/2025) is acknowledged. Rejections of claims 1-3 under 35 U.S.C. 102(a)(1) and 35 U.S.C. 112(b) have been obviated.
Election/Restrictions
3. Applicant’s election of Group I and a species wherein X = CH2 in the reply filed on 06/20/2025 is acknowledged. Because applicant did not distinctly and specifically point out the supposed errors in the restriction requirement, the election has been treated as an election without traverse (MPEP § 818.01(a)).
The examiner searched the elected invention and stopped when a prior art was found.
4. The claims are drawn to multiple inventions for reasons set forth in the restriction requirement. The claims are examined only to the extent that they read on the elected invention. Cancellation of the non-elected subject matter is recommended in response to this Office Action.
Claim Rejections - 35 USC § 102
5. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action:
A person shall be entitled to a patent unless –
(a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention.
6. Claims 1, 3 and 6 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Fisher et al. Journal of Medicinal Chemistry (2013), 56(1), 241-253. Cited reference teaches the following exemplary compounds that are the same as applicants.
PNG
media_image1.png
618
1460
media_image1.png
Greyscale
PNG
media_image2.png
531
1375
media_image2.png
Greyscale
PNG
media_image3.png
115
1433
media_image3.png
Greyscale
PNG
media_image4.png
574
997
media_image4.png
Greyscale
PNG
media_image5.png
644
1412
media_image5.png
Greyscale
PNG
media_image6.png
588
1410
media_image6.png
Greyscale
PNG
media_image7.png
171
1383
media_image7.png
Greyscale
PNG
media_image8.png
432
908
media_image8.png
Greyscale
PNG
media_image9.png
145
1443
media_image9.png
Greyscale
PNG
media_image10.png
379
999
media_image10.png
Greyscale
Since said exemplary compounds are the same as applicants, a 102(a)(1) rejection is proper.
Information Disclosure Statement
7. Applicant’s Information Disclosure Statement, filed on 12/29/2025 has been acknowledged. Please refer to Applicant’s copies of the 1449 submitted herewith.
THIS ACTION IS MADE FINAL. Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a).
A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any extension fee pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action.
Conclusion
8. Any inquiry concerning this communication or earlier communications from the examiner should be directed to Kahsay Habte Ph.D. whose telephone number is (571)272-0667. The examiner can normally be reached on 8:30 - 5:00 PM.
Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice.
If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, JEFFREY MURRAY can be reached on 571-272-9023. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300.
Information regarding the status of an application may be obtained from the Patent Application Information Retrieval (PAIR) system. Status information for published applications may be obtained from either Private PAIR or Public PAIR. Status information for unpublished applications is available through Private PAIR only. For more information about the PAIR system, see https://ppair-my.uspto.gov/pair/PrivatePair. Should you have questions on access to the Private PAIR system, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative or access to the automated information system, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000.
/Kahsay Habte/
Primary Examiner, Art Unit 1624
January 14, 2026