Last updated: May 29, 2026

Application No. 17/699,053

GENOME SEQUENCING AS AN ALTERNATIVE TO CYTOGENETIC ANALYSIS

Non-Final OA

Filed

Mar 18, 2022

Priority

Mar 18, 2021 — provisional 63/162,665

Examiner

SMITH, EMILIE ALINE

Art Unit

1686

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Washington University

OA Round

1 (Non-Final)

This examiner grants 50% of cases after interview

— +34.4% interview lift. A telephonic interview to clarify the technical implementation could significantly improve the outcome.

Based on 70 resolved cases, 2023–2026

Examiner Intelligence

SMITH, EMILIE ALINE View full profile →

Grants 50% of resolved cases

Career Allowance Rate

35 granted / 70 resolved

-10.0% vs TC avg

Strong +34% interview lift

Without

With

+34.4%

Interview Lift

resolved cases with interview

Typical timeline

4y 4m

Avg Prosecution

19 currently pending

Career history

103

Total Applications

across all art units

Statute-Specific Performance

§101

16.9%

-23.1% vs TC avg

§103

61.6%

+21.6% vs TC avg

§102

3.1%

-36.9% vs TC avg

§112

0.4%

-39.6% vs TC avg

Black line = Tech Center average estimate • Based on career data from 70 resolved cases

Prosecution Timeline

Mar 18, 2022

Application Filed

Jul 20, 2022

Response after Non-Final Action

Sep 10, 2025

Non-Final Rejection mailed

Jan 09, 2026

Response after Non-Final Action

Jan 09, 2026

Response Filed

Precedent Cases

Applications granted by this same examiner with similar technology

17/317,204

Patent 12640236

DNA CANVAS FOR INFORMATION STORAGE AND NANOFABRICATION

5y 0m to grant Granted May 26, 2026

17/205,395

Patent 12626790

POINT-OF-CARE TESTING (POCT) INSTRUMENT AND POCT SYSTEM

5y 1m to grant Granted May 12, 2026

17/074,984

Patent 12603150

CALCULATING CELL-TYPE RNA PROFILES FOR DIAGNOSIS AND TREATMENT

5y 5m to grant Granted Apr 14, 2026

18/929,229

Patent 12602520

MACHINE-LEARNING VIRTUALIZATION-ENABLED HARVESTING

1y 5m to grant Granted Apr 14, 2026

17/224,496

Patent 12586661

HARDWARE ACCELERATED K-MER GRAPH GENERATION

4y 11m to grant Granted Mar 24, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

1-2

Expected OA Rounds

50%

Grant Probability

84%

With Interview (+34.4%)

4y 4m (~2m remaining)

Median Time to Grant

Low

PTA Risk

Based on 70 resolved cases by this examiner. Grant probability derived from career allowance rate.