Prosecution Insights
Last updated: April 19, 2026
Application No. 17/765,776

Patient-Specific Breast Implant for Breast Reconstruction after Breast-Conserving Mastectomy

Non-Final OA §103
Filed
Mar 31, 2022
Examiner
BLASS, PARIS MARIE
Art Unit
3774
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Osong Medical Innovation Foundation
OA Round
3 (Non-Final)
59%
Grant Probability
Moderate
3-4
OA Rounds
3y 9m
To Grant
99%
With Interview

Examiner Intelligence

Grants 59% of resolved cases
59%
Career Allow Rate
13 granted / 22 resolved
-10.9% vs TC avg
Strong +47% interview lift
Without
With
+47.4%
Interview Lift
resolved cases with interview
Typical timeline
3y 9m
Avg Prosecution
48 currently pending
Career history
70
Total Applications
across all art units

Statute-Specific Performance

§101
0.9%
-39.1% vs TC avg
§103
48.4%
+8.4% vs TC avg
§102
30.8%
-9.2% vs TC avg
§112
15.2%
-24.8% vs TC avg
Black line = Tech Center average estimate • Based on career data from 22 resolved cases

Office Action

§103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. Continued Examination Under 37 CFR 1.114 A request for continued examination under 37 CFR 1.114, including the fee set forth in 37 CFR 1.17(e), was filed in this application after final rejection. Since this application is eligible for continued examination under 37 CFR 1.114, and the fee set forth in 37 CFR 1.17(e) has been timely paid, the finality of the previous Office action has been withdrawn pursuant to 37 CFR 1.114. Applicant's submission filed on 01/07/2026 has been entered. Response to Amendment The amendment filed 01/07/2026 has been entered. Claims 1, 4-5, 7-8, and 10-15 remain pending in the application. Response to Arguments Applicant's arguments filed 01/07/2026 have been fully considered but they are not persuasive. Applicant argues that Chitre fails to disclose that “an exterior surface of the shape memory film is openly exposed and forms an openly exposed outer surface of the shell portion” as now required by amended claim 1 because even assuming that reinforcement layer 40 and/or intermediate layer 26 were formed from a shape memory polymer, both layers 40 and 26 are fully covered. However, a new interpretation of Chitre has been set forth below in which the shape memory film is now considered to comprise the collective of layers 38, 40, 36, and 26, in which layers 26 and 40 impart the shape memory characteristics of the shape memory film and layer 38 forms the openly exposed layer of the shape memory film. Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. The factual inquiries for establishing a background for determining obviousness under 35 U.S.C. 103 are summarized as follows: 1. Determining the scope and contents of the prior art. 2. Ascertaining the differences between the prior art and the claims at issue. 3. Resolving the level of ordinary skill in the pertinent art. 4. Considering objective evidence present in the application indicating obviousness or nonobviousness. Claim 1, 4, 7, 8, and 12-15 are rejected under 35 U.S.C. 103 as being unpatentable over US 2011/0270391 A1 (hereafter --Chitre--), in view of US 20170258574 A1 (hereafter --Hutmacher--). Regarding Claim 1, Chitre discloses a patient-specific breast implant configured to be inserted into a breast tissue removal site of a human after a partial mastectomy (see paragraph [0018]), comprising: a shell portion constituting an outer wall (see the annotated shell portion in Figure 1 below) that bounds a compartment (see annotated compartment in Figure 1 below), the shell portion having an original shape that is complementary to a shape of an inner space of a breast wherein the inner space is formed by a breast tissue expander (see annotated breast implant and breast tissue expander in Figure 1 below), the shell portion comprising: a silicone film made of silicone (24) and a shape memory film (38, 40, 36, and 26) (see paragraph [0081] denoting that the layer 22 is made of silicone, see paragraphs [0084]-[0085] denoting that the outer and inner layers 22 and 24 can be made of the same material, see also paragraph [0086] denoting that the layers are coupled together with silicone gel, see also paragraphs see paragraph [0044] denoting that the intermediate layer 26 provides a shape memory characteristic to the assembly, see also paragraph [0080] denoting that the layer 40 comprises of a synthetic polymer like polyurethane or polyethylene, both of which are known within the skill of the art to have shape memory properties, see paragraph [0078] denoting layers 36 and 38 are made of elastomeric material, the layer 38 forming an openly exposed layer of the shell) overlaying the silicone film so that an exterior surface (38) of the shape memory film is openly exposed and forms an openly exposed outer surface of the shell portion (see annotated layers 26, 36, 40, and 38 being overlayed over layer 24, the layers 26, 40, and 38 being an integral layer in forming the annotated openly exposed outer surface in Figure 1 below, see paragraph [0078] denoting layers 36 and 38 are made of elastomeric material, the layer 38 forming an openly exposed layer of the shell), and a filler disposed within the compartment bounded by the shell portion (see annotated filler in Figure 1 below). Chitre fails to disclose wherein the shape memory film being comprised of a shape-memory polymer that is recoverable in shape when subject to the physiological body-temperature range of a human so that when the breast implant is disposed within the breast tissue removal site and an external force deforms the shell portion to a temporary shape, the shell portion automatically returns to the original shape when the external force is removed. Hutmacher discloses a breast implant for breast reconstruction or augmentation, on use case being for after a mastectomy (see paragraph [0036], [0076], and [0077]), wherein the implant has a shape memory polymer material (see paragraphs [0109] and [0111]). Hutmacher teaches wherein the shape memory material being comprised of a shape-memory polymer that is recoverable in shape when subject to the physiological body-temperature range of a human so that when the breast implant is disposed within the breast tissue removal site and an external force deforms the shell portion to a temporary shape, the shell portion automatically returns to the original shape when the external force is removed (see paragraphs [0109] and [0111]). Therefore, it would have been obvious to one of ordinary skill in the art before the effective filing date of invention to have modified the shape memory film of Chitre to be comprised of a shape-memory polymer that is recoverable in shape when subject to the physiological body-temperature range of a human so that when the breast implant is disposed within the breast tissue removal site and an external force deforms the shell portion to a temporary shape, the shell portion automatically returns to the original shape when the external force is removed as taught by Hutmacher, as by as doing so would allow the surgeon to reduce the amount of tissue injury during implantation and thus permits the use of minimally invasive procedures (see paragraph [0111]). PNG media_image1.png 573 891 media_image1.png Greyscale Regarding Claim 4, Chitre as modified discloses the patient-specific breast implant of claim 1, wherein the shape-memory polymer material is polyurethane (see Hutmacher’s paragraph [0039]). Regarding Claim 7, Chitre as modified discloses the patient-specific breast implant of claim 1, wherein the shape-memory polymer (material of 38, 40, 36, and 26) is on an outer surface of the silicone film (24) (see in Figure 1 above that the layers 38, 40, 36, and 26 is formed on an outer surface of the silicone film layer 24). The limitation “formed through a surface treatment” is being treated as a product by process limitation; that is the shape memory film is formed through surface treatment. As set forth in MPEP 2113, product-by-process claims are NOT limited to the manipulations of the recited steps, only to the structure implied by the steps. The patentability of a product does not depend on its method of production. If the product in the product-by-process claim is the same as or obvious from a product of the prior art, the claim is unpatentable even though the prior product was made by a different process." In re Thorpe, 777 F.2d 695, 698, 227 USPQ 964, 966 (Fed. Cir. 1985). Thus, even though Chitre is silent as to the process used to make the shape memory film, it appears that the breast implant would be the same or similar as that claimed; especially since both applicant’s breast implant and the prior art breast implant comprise a shell portion comprising a shape memory film made of a shape memory polymer formed on an outer surface of a silicone film made of silicone. Regarding Claim 8, Chitre as modified discloses the patient-specific breast implant of claim 7 comprising a silicone film (see claim 7 rejection above). The limitation “is formed through 3D printing” is being treated as a product by process limitation; that is the silicone film is made by 3D printing. As set forth in MPEP 2113, product-by-process claims are NOT limited to the manipulations of the recited steps, only to the structure implied by the steps. The patentability of a product does not depend on its method of production. If the product in the product-by-process claim is the same as or obvious from a product of the prior art, the claim is unpatentable even though the prior product was made by a different process." In re Thorpe, 777 F.2d 695, 698, 227 USPQ 964, 966 (Fed. Cir. 1985). Thus, even though Chitre is silent as to the process used to make the silicone film, it appears that the breast implant would be the same or similar as that claimed; especially since both applicant’s breast implant and the prior art breast implant comprise a shell portion comprising a silicone film made of silicone. Regarding Claim 12, Chitre as modified discloses the patient-specific breast implant of claim 1. Chitre as modified fails to disclose further comprising a fixing portion protruding from the outer surface of the shell portion. Chitre teaches in another embodiment a fixing portion protruding from the outer surface of the shell portion (see annotated fixing portion 128 in Figure 6 below). Therefore, it would have been obvious to one of ordinary skill in the art before the effective filing date of invention to have the implant of Fig. 1 further comprise a fixing portion protruding from the outer surface of the shell portion as taught by Chitre in the embodiment of Fig. 6, as by doing so would facilitate rolling or folding of device during insertion (see paragraph [0110]). PNG media_image2.png 234 646 media_image2.png Greyscale Regarding Claim 13, Chitre as modified discloses the patient-specific breast implant of claim 1, wherein the shape memory film having the openly exposed exterior surface (38) is disposed directly on an outer surface of the silicone film and the silicone film is disposed directly on the filler (see annotated openly exposed outer surface of shape memory film 38, see also annotated layer 26 (which is a part of the shape memory film), being directly on the surface of the silicone film 24, and the silicone film being directly on the annotated filler 28 in Figures 1 and 2). Regarding Claim 14, Chitre as modified discloses the patient-specific breast implant of claim 1, wherein the silicone film and the shape memory film completely surround the compartment in which the filler is disposed so that the silicone film and the shape memory film completely enclose the filler (see annotated filler, compartment, silicone film 24, and shape memory film 38, 40, 36, and 26 in Figure 1 above). Regarding Claim 15, Chitre as modified discloses the patient-specific breast implant of claim 1, wherein the shape memory film comprises the shape-memory polymer extending from the exposed exterior surface (38) of the shape memory film to an opposing interior surface of the shape memory film (see annotated exposed outer surface and annotated interior surface of shape memory film layer 38, 40, 36, and 26 in Figures 1 and 2 above), the interior surface of the shape memory film being disposed directly on an outer surface of the silicone film (see also annotated layer 26 (which is a part of the shape memory film, 26 being the “interior surface”), being directly on the “outer” surface of the silicone film 24). Claim 5 is rejected under 35 U.S.C. 103 as being unpatentable over US 20110270391 A1 (hereafter --Chitre--) in view of US 20170258574 A1 (hereafter --Hutmacher--), as applied to claim 4 above, and further view of US 20190247180 A1 (hereafter --Limem--) Regarding Claim 5, Chitre as modified discloses the patient-specific breast implant of claim 4. Chitre fails to disclose wherein the shape-memory polymer material is the polyester-based polymer, and the polyester-based polymer is any one or a combination of two or more that are selected from polyphosphazene, polyanhydride, poly acetal, polyorthoester, polyphosphoester, polyglycolide, poly-F-caprolactone, polylactide, polycarbonate, and polyamide. Limem discloses a breast implant with a shell forming an outer wall of the implant (see annotated implant and shell in Figures 6B and 6A below), wherein the shell portion comprises a shape memory polymer (see paragraph [0167]). Limem teaches the polymer material is the polyester-based polymer, and the polyester-based polymer is any one or a combination of two or more that are selected from polyphosphazene, polyanhydride, polyorthoester, polyphosphoester, polylactide, polycarbonate, and polyamide (see paragraph [0104]). PNG media_image3.png 304 701 media_image3.png Greyscale Therefore, it would have been obvious to one having ordinary skill in the art before the effective filing date of the claimed invention for the polymer of Chitre in view of Hutmacher to be a combination of two or more polymers that are selected from polyphosphazene, polyanhydride, polyorthoester, polyphosphoester, polylactide, polycarbonate, and polyamide since they are known materials for breast implants as taught by Limem (see paragraph [0167]) and, further, since it has been held to be within the general skill of a worker in the art to select a known material on the basis of its suitability for the intended use as a matter of obvious design choice. In re Leshin, 125 USPQ 416. The limitation “which are certified to be harmless when inserted into the human body” is inherently disclosed as the materials used for the implants are biocompatible, meaning they are compatible with living tissue and are nontoxic, injurious, or physiologically reactive and not causing immunological rejection (Merriam-Webster online dictionary), and these materials are certified for biocompatibility in medical device manufacturing. Claims 10 and 11 are rejected under 35 U.S.C. 103 as being unpatentable over US 20110270391 A1 (hereafter --Chitre--) in view of US 20170258574 A1 (hereafter --Hutmacher--), as applied to claim 1 above, in further view of US 20110276136 A1 (hereafter --Koole--). Regarding Claim 10, Chitre as modified discloses the patient-specific breast implant of claim 1. Chitre fails to disclose wherein the filler is made of a shape memory polymer. Koole discloses a breast implant that has an outer shell portion that is an outer wall that is filled with a core filling material (see Figure 1 below, see also Abstract). Koole teaches that it is well known in the art for the filler of a breast implant to be made of a shape memory polymer (see paragraph [0004] describing the “cohesive gel” filler option having shape memory properties). PNG media_image4.png 609 439 media_image4.png Greyscale Therefore, it would have been obvious to one having ordinary skill in the art before the effective filing date of the claimed invention to change the material of the filler of the breast implant of Chitre in view of Hutmacher to be made of a shape memory polymer, as by doing would enable the filler of the implant to retain its shape and volume (due to its shape memory properties) as they reside within the shell cavity in the event of a rupture, compared to implants that are filled with silicone gel (without shape memory) that would escape from the shell and spread into the surrounding tissues in the event of a rupture as taught by Koole (see paragraph [0004]). Regarding Claim 11, Chitre as modified discloses the patient-specific breast implant of claim 10, wherein the shape memory film of the shell portion is made of a shape memory polymer (see paragraphs see paragraph [0044] denoting that the intermediate layer 26 provides a shape memory characteristic to the assembly, see also paragraph [0080] denoting that the layer 40 comprises of a synthetic polymer like polyurethane or polyethylene, both of which are known within the skill of the art to have shape memory properties, and Hutmacher’s paragraph [0039]). The limitation “formed through 3D printing” is being treated as a product by process limitation; that is the shell portion and the filler are made by 3D printing. As set forth in MPEP 2113, product-by-process claims are NOT limited to the manipulations of the recited steps, only to the structure implied by the steps. The patentability of a product does not depend on its method of production. If the product in the product-by-process claim is the same as or obvious from a product of the prior art, the claim is unpatentable even though the prior product was made by a different process." In re Thorpe, 777 F.2d 695, 698, 227 USPQ 964, 966 (Fed. Cir. 1985). Thus, even though Chitre as modified is silent as to the process used to make the filler and the shell portion, it appears that the breast implant would be the same or similar as that claimed; especially since both applicant’s breast implant and the prior breast implant comprise a shell and filler that are both made of only shape memory polymers. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to PARIS MARIE BLASS whose telephone number is (703)756-5375. The examiner can normally be reached Monday - Thursday 9 a.m. - 7 p.m. ET. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Melanie Tyson can be reached at 571-272-9062. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /PARIS MARIE BLASS/Examiner, Art Unit 3774 /MELANIE R TYSON/Supervisory Patent Examiner, Art Unit 3774
Read full office action

Prosecution Timeline

Mar 31, 2022
Application Filed
Mar 31, 2022
Response after Non-Final Action
Mar 05, 2025
Non-Final Rejection — §103
Jun 30, 2025
Response Filed
Sep 03, 2025
Final Rejection — §103
Dec 23, 2025
Interview Requested
Jan 07, 2026
Request for Continued Examination
Jan 15, 2026
Applicant Interview (Telephonic)
Jan 15, 2026
Examiner Interview Summary
Feb 12, 2026
Response after Non-Final Action
Mar 04, 2026
Non-Final Rejection — §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
59%
Grant Probability
99%
With Interview (+47.4%)
3y 9m
Median Time to Grant
High
PTA Risk
Based on 22 resolved cases by this examiner. Grant probability derived from career allow rate.

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