Prosecution Insights
Last updated: April 19, 2026
Application No. 17/770,320

SYSTEMS AND COMPONENTS FOR DRUG DELIVERY AND COMPONENTS FOR PREPARATION OF THE SAME

Final Rejection §102§103
Filed
Apr 20, 2022
Examiner
KIM, ERIN ASA
Art Unit
3781
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Amgen, Inc.
OA Round
4 (Final)
72%
Grant Probability
Favorable
5-6
OA Rounds
2y 11m
To Grant
99%
With Interview

Examiner Intelligence

Grants 72% — above average
72%
Career Allow Rate
59 granted / 82 resolved
+2.0% vs TC avg
Strong +31% interview lift
Without
With
+31.3%
Interview Lift
resolved cases with interview
Typical timeline
2y 11m
Avg Prosecution
25 currently pending
Career history
107
Total Applications
across all art units

Statute-Specific Performance

§101
0.7%
-39.3% vs TC avg
§103
59.7%
+19.7% vs TC avg
§102
20.2%
-19.8% vs TC avg
§112
17.3%
-22.7% vs TC avg
Black line = Tech Center average estimate • Based on career data from 82 resolved cases

Office Action

§102 §103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Response to Arguments Applicant’s arguments filed 1/25/2025 have been considered but are moot because the new ground of rejection does not rely on any reference applied in the prior rejection of record for any teaching or matter specifically challenged in the argument. Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 14-15, 21-22, 25-27 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Haber et al. (US 5647845 A, hereafter “Haber”). Regarding claim 14, Haber discloses a device (1) for use with a drug vial (100) having a cap (fig. 1), comprising: a cap clasp (20) having at least two arms (28) adapted to selectively couple with the cap of the vial (column 5 lines 46-52); a vial spike (16) generally centrally located between the at least two arms (28) and configured to pierce a seal of the vial (column 8 line 67 – column 9 line 2); an intravenous (IV) line (82, fig. 12, column 8 lines 17-20) coupled with the vial spike (16, although fig. 8 shows the closed valve position not permitting flow, the spike 16 can connect to the pathway of the IV drip chamber); a valve (8) having a first position wherein the valve is configured to prevent fluid communication with the IV line (column 9 lines 14-19, no communication with the IV line) and a second position wherein the valve (8) is configured to allow fluid communication with the IV line (column 9 lines 32-47); and a port (14) configured to allow fluid to be added to the device via a pathway separate from the vial spike (16) when the valve is in the first position (column 8 lines 8-18). Regarding claim 15, Haber discloses the device of claim 14 and further discloses wherein the at least two arms (28) are flexibly positionable around the cap of the vial (figs. 2A and 2B, column 5 lines 53-67). Regarding claim 21, Haber discloses the device of claim 14 and further discloses wherein the port (14) is configured to allow the fluid to be added to the device for mixing with drug from the drug vial when the valve is in the first position (column 9 lines 14-19). Regarding claim 22, Haber discloses the device of claim 14 and further discloses connecting the IV line and a hub (2), wherein the hub is directly coupled with the IV line (82), the vial spike (16), and the port (14, fig. 12). Regarding claim 25, Haber discloses the device of claim 14 and further discloses wherein the cap clasp comprises a third arm (28) adapted to selectively couple with the cap of the vial (figs. 2A and 2B). Regarding claim 26, Haber discloses the device of claim 25 and further discloses wherein the cap clasp comprises a fourth arm (28) adapted to selectively couple with the cap of the vial (figs. 2A and 2B). Regarding claim 27, Haber discloses the device of claim 26 and further discloses wherein the at least two arms, the third arm, and the fourth arm are circumferentially spaced around an outer periphery of the cap clasp 9figs. 2A and 2B). Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. The factual inquiries for establishing a background for determining obviousness under 35 U.S.C. 103 are summarized as follows: 1. Determining the scope and contents of the prior art. 2. Ascertaining the differences between the prior art and the claims at issue. 3. Resolving the level of ordinary skill in the pertinent art. 4. Considering objective evidence present in the application indicating obviousness or nonobviousness. This application currently names joint inventors. In considering patentability of the claims the examiner presumes that the subject matter of the various claims was commonly owned as of the effective filing date of the claimed invention(s) absent any evidence to the contrary. Applicant is advised of the obligation under 37 CFR 1.56 to point out the inventor and effective filing dates of each claim that was not commonly owned as of the effective filing date of the later invention in order for the examiner to consider the applicability of 35 U.S.C. 102(b)(2)(C) for any potential 35 U.S.C. 102(a)(2) prior art against the later invention. Claim(s) 23 and 24 is/are rejected under 35 U.S.C. 103 as being unpatentable over Haber (US 5647845 A). Regarding claim 23, Haber discloses the device of claim 14 and an IV line (82, fig. 12). However, Haber fails to expressly disclose wherein at least a portion of the IV line comprises at least one bend and/or is configured to bend during removal of the device from the vial. While features of an apparatus may be recited either structurally or functionally, claims directed to a device must be distinguished from the prior art in terms of structure rather than function, because device claims cover what a device is, not what a device does (MPEP 2114). Thus, if a prior art structure is capable of performing the intended use as recited in the preamble, or elsewhere in a claim, then it meets the claim. In this case, the IV line of Haber is capable of performing the claimed function bending while the device is moved around when the vial is removed because the claim nor the specification discloses a non-traditional type of IV line that is well known to be flexible tubing that can be bent or twisted due to its flexible, often plastic, material. Regarding claim 24, Haber discloses the device of claim 14 and the vial spike (16) and IV line (82). However, Haber fails to disclose wherein the vial spike and IV line are provided as a single, pre-assembled unit; rather, the IV line is a separate tube that is fitted into the port of the drip chamber of the device to establish a fluid connection. Haber discloses the claimed invention except for that single, pre-assembled unit of the vial spike and the IV line. It would have been obvious to one having ordinary skill in the art at the effective filing date of the invention to have the IV line integrally formed with the device to create one single unit, since it has been held that forming a single assembly which has formerly been formed in two pieces and put together involves only routine skill in the art. MPEP 2144.04 V.B. Claim(s) 16 is/are rejected under 35 U.S.C. 103 as being unpatentable over Haber (US 5647845 A) in view of Bloom et al. (US 4128098 A). Haber discloses the device of claim 14 but fails to disclose wherein the vial spike includes at least one slot formed thereon. Bloom teaches a similar device in the same field of endeavor wherein the vial spike includes at least one slot formed thereon (fig. 5, column 2 lines 36-41). It would have been obvious to one of ordinary skill in the art before the effective filing date of the claimed invention to have modified the spike of Haber and incorporate the slotted spike of Bloom to allow air to enter the passage to avoid a vacuum in the vial (column 2 lines 36-41). Conclusion Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to ERIN A KIM whose telephone number is (703)756-4738. The examiner can normally be reached Monday - Friday 8:00 am - 5:00 pm (EST). Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Rebecca Eisenberg can be reached at (571) 270-5879. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /ERIN A KIM/Examiner, Art Unit 3781 /SUSAN S SU/Primary Examiner, Art Unit 3781 9 February 2026
Read full office action

Prosecution Timeline

Apr 20, 2022
Application Filed
Jan 27, 2025
Non-Final Rejection — §102, §103
Apr 10, 2025
Response Filed
Apr 21, 2025
Final Rejection — §102, §103
Jun 03, 2025
Response after Non-Final Action
Jun 30, 2025
Request for Continued Examination
Jul 03, 2025
Response after Non-Final Action
Aug 21, 2025
Non-Final Rejection — §102, §103
Nov 25, 2025
Response Filed
Feb 09, 2026
Final Rejection — §102, §103 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

5-6
Expected OA Rounds
72%
Grant Probability
99%
With Interview (+31.3%)
2y 11m
Median Time to Grant
High
PTA Risk
Based on 82 resolved cases by this examiner. Grant probability derived from career allow rate.

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