Last updated: May 29, 2026

Application No. 17/818,885

HUMANIZED ANTI-C1S ANTIBODIES AND METHODS OF USE THEREOF

Non-Final OA

Filed

Aug 10, 2022

Priority

Apr 06, 2015 — provisional 62/143,636 +5 more

Examiner

HOWARD, ZACHARY C

Art Unit

1674

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Bioverativ Usa Inc.

OA Round

1 (Non-Final)

This examiner grants 64% of cases after interview

— +38.2% interview lift. A telephonic interview to clarify the technical implementation could significantly improve the outcome.

Based on 947 resolved cases, 2023–2026

Examiner Intelligence

HOWARD, ZACHARY C View full profile →

Grants 64% of resolved cases

Career Allowance Rate

605 granted / 947 resolved

+3.9% vs TC avg

Strong +38% interview lift

Without

With

+38.2%

Interview Lift

resolved cases with interview

Typical timeline

2y 9m

Avg Prosecution

48 currently pending

Career history

997

Total Applications

across all art units

Statute-Specific Performance

§101

2.2%

-37.8% vs TC avg

§103

27.7%

-12.3% vs TC avg

§102

18.0%

-22.0% vs TC avg

§112

31.0%

-9.0% vs TC avg

Black line = Tech Center average estimate • Based on career data from 947 resolved cases

Prosecution Timeline

Aug 10, 2022

Application Filed

Dec 04, 2025

Non-Final Rejection (signed)

Jan 22, 2026

Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

17/560,022

Patent 12624088

CHIMERIC RECEPTOR COMPRISING A LIGAND BINDING DOMAIN AND AN ENDODOMAIN COMPRISING A CYTOKINE RECEPTOR ENDODOMAIN AND AN INTRACELLULAR T CELL SIGNALLING DOMAIN

4y 4m to grant Granted May 12, 2026

18/750,581

Patent 12616749

COMPOSITIONS AND METHODS FOR TREATMENT OF PSORIASIS

1y 10m to grant Granted May 05, 2026

17/642,837

Patent 12599654

IMMUNOGENIC PEPTIDE FRAGMENTS OF METALLOPROTEASE ADAMTS-7 AND USES THEREOF IN ANTI-ATHEROSCLEROSIS AND RELATED DISEASES

4y 1m to grant Granted Apr 14, 2026

17/814,221

Patent 12582712

Method of Making Anti-Pro/Latent Myostatin Antibodies

3y 8m to grant Granted Mar 24, 2026

17/645,211

Patent 12577300

NEUTRALIZING ANTIBODIES TO HUMAN ENDOTHELIN

4y 2m to grant Granted Mar 17, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

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Prosecution Projections

1-2

Expected OA Rounds

64%

Grant Probability

99%

With Interview (+38.2%)

2y 9m (~0m remaining)

Median Time to Grant

Low

PTA Risk

Based on 947 resolved cases by this examiner. Grant probability derived from career allowance rate.