Prosecution Insights
Last updated: October 04, 2026
Application No. 17/866,672

QUINOXALINE DERIVATIVES

Final Rejection §102§112
Filed
Jul 18, 2022
Priority
Jan 17, 2020 — EU 20152469.1 +1 more
Examiner
WARD, PAUL V
Art Unit
1622
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Gruenenthal GmbH
OA Round
2 (Final)
83%
Grant Probability
Favorable
3-4
OA Rounds
0m
Est. Remaining
71%
With Interview

Examiner Intelligence

Grants 83% — above average
83%
Career Allowance Rate
1417 granted / 1704 resolved
+23.2% vs TC avg
Minimal -12% lift
Without
With
+-12.2%
Interview Lift
resolved cases with interview
Typical timeline
2y 4m
Avg Prosecution
60 currently pending
Career history
1729
Total Applications
across all art units

Statute-Specific Performance

§101
5.4%
-34.6% vs TC avg
§103
20.4%
-19.6% vs TC avg
§102
18.8%
-21.2% vs TC avg
§112
42.3%
+2.3% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1704 resolved cases

Office Action

§102 §112
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . DETAILED ACTION STATUS OF THE CLAIMS: Claims 1 and 3-17 are pending in this application. Response to Arguments & Amendment Under Claim Rejections - 35 USC § 112, 1st and 2nd paragraphs Applicant’s arguments and amendment filed April 15, 2026, with respect to the rejections of claims under 35 USC § 112, 1st and 2nd paragraphs have been fully considered and are persuasive. Therefore, the rejections has been withdrawn. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale or otherwise available to the public before the effective filing date of the claimed invention. Claims 1 and 3-10 and 12 are rejected under 35 U.S.C. 102 as being anticipated by Lecomte et al. (J’nal of ACS’2019). This reference discloses Applicant’s compound and the following STN compound: PNG media_image1.png 203 329 media_image1.png Greyscale The compound reads on the instant claims. Since this reference teaches the exact compound, Applicant’s claims are anticipated, and thus, rejected under 35 U.S.C. 102. Allowable Subject Matter Claims 11 and 13 are allowed. The compound and composition in claims 11 and 13 were not found to be obvious or anticipated by the prior art of record. The prior art does not teach or suggest the compounds substituted in the manner claimed by the Applicant. Therefore, these claims are allowed. Claims 15 and 17 will be rejoined and allowed if the status (i.e., “Withdrawn”) is changed. Conclusion Claims 1 and 3-17 are pending in this application. Claims 1, 3-10 and 12 are rejected. Claims are 11 and 13 are allowed. THIS ACTION IS MADE FINAL. Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to PAUL V WARD whose telephone number is (571)272-2909. The examiner can normally be reached M-F 9am to 5pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, James Alstrum-Acevedo can be reached at 571-272-5548. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /PAUL V WARD/ Primary Examiner, Art Unit 1622
Read full office action

Prosecution Timeline

Jul 18, 2022
Application Filed
Jan 22, 2026
Non-Final Rejection mailed — §102, §112
Apr 15, 2026
Response Filed
Sep 02, 2026
Final Rejection mailed — §102, §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
83%
Grant Probability
71%
With Interview (-12.2%)
2y 4m (~0m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 1704 resolved cases by this examiner. Grant probability derived from career allowance rate.

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