Prosecution Insights
Last updated: April 19, 2026
Application No. 17/906,194

COENZYME Q PRODUCTION ACCELERATOR AND METHOD FOR ACCELERATING COENZYME Q PRODUCTION

Final Rejection §102§112
Filed
Sep 13, 2022
Examiner
LEWIS, PATRICK T
Art Unit
1691
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Tsunemaru Tanaka
OA Round
2 (Final)
74%
Grant Probability
Favorable
3-4
OA Rounds
2y 6m
To Grant
89%
With Interview

Examiner Intelligence

Grants 74% — above average
74%
Career Allow Rate
844 granted / 1135 resolved
+14.4% vs TC avg
Moderate +14% lift
Without
With
+14.3%
Interview Lift
resolved cases with interview
Typical timeline
2y 6m
Avg Prosecution
40 currently pending
Career history
1175
Total Applications
across all art units

Statute-Specific Performance

§101
4.0%
-36.0% vs TC avg
§103
30.5%
-9.5% vs TC avg
§102
20.4%
-19.6% vs TC avg
§112
21.4%
-18.6% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1135 resolved cases

Office Action

§102 §112
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Applicant’s Response Dated August 21, 2025 In the Response dated August 21, 2025, claims 2 and 6 were amended, and claims 1 and 3-5 were canceled. Claims 2 and 6 are pending. An action on the merits of claims 2 and 6 is contained herein. The rejection of claim 2 under 35 U.S.C. 101 has been rendered moot in view of applicant’s amendment dated August 21, 2025. The rejection of claim 2 under 35 U.S.C. 102(a)(1) and 102(a)(2) as being anticipated by Seals et al. WO 2015/148522 A1 (Seals) is maintained for the reasons of record as set forth in the Office Action dated May 22, 2025. The rejection of claim 2 under 35 U.S.C. 102(a)(1) as being anticipated by Ummarino et al. Food Chemistry (2017), Vol. 221, pages 161-168 (Ummarino) has been rendered moot in view of applicant’s amendment dated August 21, 2025. The rejection of claim 6 under 35 U.S.C. 102(a)(1) and 102(a)(2) as being anticipated by Seals et al. WO 2015/148522 A1 (Seals) is maintained for the reasons of record as set forth in the Office Action dated May 22, 2025. The rejection of claim 6 under 35 U.S.C. 103 as being unpatentable over Ummarino et al. Food Chemistry (2017), Vol. 221, pages 161-168 (Ummarino); Akkerman, Renate, Marijke M. Faas, and Paul de Vos. "Non-digestible carbohydrates in infant formula as substitution for human milk oligosaccharide functions: Effects on microbiota and gut maturation." Critical Reviews in Food Science and Nutrition 59.9 (2019): 1486-1497 (Akkerman); and Mulol, Helen, and Anna Coutsoudis. "Breastmilk output in a disadvantaged community with high HIV prevalence as determined by the deuterium oxide dose-to-mother technique." Breastfeeding Medicine 11.2 (2016): 64-69 (Mulol) in combination has been rendered moot in view of applicant’s amendment dated August 21, 2025. Rejections Set Forth in the Office Action Dated May 22, 2025 The text of those sections of Title 35, U.S. Code not included in this action can be found in a prior Office action. Claims 2 and 6 is/are rejected under 35 U.S.C. 102(a)(1) and 102(a)(2) as being anticipated by Seals et al. WO 2015/148522 A1 (Seals). Applicant's arguments filed August 21, 2025 have been fully considered but they are not persuasive. Claims 2 and 6 have been amended. Applicant submits that claim 6 is no longer subject to the § 102 rejection. Applicant’s arguments have been fully considered. However, applicant's arguments fail to comply with 37 CFR 1.111(b) because they amount to a general allegation that the claims define a patentable invention without specifically pointing out how the language of the claims patentably distinguishes them from the references. As set forth in the last Office Action, Seals teaches a method of treating vascular endothelial dysfunction comprising administering a daily dose of a composition comprising from about 1 mg to about 25 mg per kg body weight per day. A subject having vascular endothelial dysfunction (e.g., cardiovascular disease) is embraced by an instant target as vascular endothelial dysfunction (e.g., cardiovascular disease) is embraced by “lifestyle-related diseases” as it is related to diet and exercise. Thus, the rejection(s) is maintained. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claims 2 and 6 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Regarding claim 6, the term “lifestyle-related diseases” renders the claim(s) indefinite as the term is not defined in the claims or specification. It is unclear what disease(s), and by extension what target(s), applicant intends to be part of the claimed invention. For example, it is unclear whether applicant intends for “lifestyle-related diseases” to include cardiovascular disease. Forman, Daniel, and Bernard E. Bulwer. "Cardiovascular disease: optimal approaches to risk factor modification of diet and lifestyle." Current treatment options in cardiovascular medicine 8.1 (2006): 47-57 (Forman) teaches that as much as 70% of CVD can be prevented or delayed with dietary choices and lifestyle modifications (Opinion Statement). Forman teaches that Western-style diets, sedentary lifestyles, and cigarette smoking are key modifiable CVD risk factors. For the purposes of applying art, the examiner interprets the term to include cardiovascular disease and/or any other disease or condition that is related to lifestyle. Conclusion Claims 2 and 6 are pending. Claims 2 and 6 are rejected. No claims are allowed. Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Contacts Any inquiry concerning this communication or earlier communications from the examiner should be directed to PATRICK T LEWIS whose telephone number is (571)272-0655. The examiner can normally be reached Monday to Friday, 10 AM to 4 PM EST (Maxi Flex). Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Shaojia Jiang can be reached at (571) 272-0627. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /PATRICK T LEWIS/Primary Examiner, Art Unit 1691 /PL/
Read full office action

Prosecution Timeline

Sep 13, 2022
Application Filed
May 19, 2025
Non-Final Rejection — §102, §112
Aug 21, 2025
Response Filed
Oct 14, 2025
Final Rejection — §102, §112 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12599594
Treatment Of Fabry Disease In ERT-Naïve And ERT-Experienced Patients
2y 5m to grant Granted Apr 14, 2026
Patent 12599595
Dosing Regimens for the Treatment of Lysosomal Storage Diseases Using Pharmacological Chaperones
2y 5m to grant Granted Apr 14, 2026
Patent 12595281
Indodicarbocyanine Phosphoramidites with Bathochromically Shifted Absorption and Emission, and Tunable Hydrophobicity
2y 5m to grant Granted Apr 07, 2026
Patent 12594292
ANTIVIRAL PRODRUGS, INTERMEDIATE-AND LONG-ACTING FORMULATIONS AND METHODS
2y 5m to grant Granted Apr 07, 2026
Patent 12584124
MAGNETIC BEAD BASED NUCLEIC ACID EXTRACTION SYSTEM
2y 5m to grant Granted Mar 24, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

AI Strategy Recommendation

Get an AI-powered prosecution strategy using examiner precedents, rejection analysis, and claim mapping.
Powered by AI — typically takes 5-10 seconds

Prosecution Projections

3-4
Expected OA Rounds
74%
Grant Probability
89%
With Interview (+14.3%)
2y 6m
Median Time to Grant
Moderate
PTA Risk
Based on 1135 resolved cases by this examiner. Grant probability derived from career allow rate.

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month