Prosecution Insights
Last updated: May 29, 2026
Application No. 17/911,312

A Method of Enhancing Ethanol Fermentation

Non-Final OA §103
Filed
Sep 13, 2022
Priority
Mar 16, 2020 — GB 2003765.1 +1 more
Examiner
FRONDA, CHRISTIAN L
Art Unit
1652
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Lytegro Limited
OA Round
1 (Non-Final)
82%
Grant Probability
Favorable
1-2
OA Rounds
0m
Est. Remaining
96%
With Interview

Examiner Intelligence

Grants 82% — above average
82%
Career Allowance Rate
1104 granted / 1339 resolved
+22.4% vs TC avg
Moderate +14% lift
Without
With
+14.1%
Interview Lift
resolved cases with interview
Typical timeline
2y 5m
Avg Prosecution
40 currently pending
Career history
1382
Total Applications
across all art units

Statute-Specific Performance

§101
0.4%
-39.6% vs TC avg
§103
28.2%
-11.8% vs TC avg
§102
7.4%
-32.6% vs TC avg
§112
23.0%
-17.0% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1339 resolved cases

Office Action

§103
DETAILED ACTION The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Applicant’s election of Invention 3 in the reply filed on 07/15/2025 is acknowledged. Because applicant did not distinctly and specifically point out the supposed errors in the restriction requirement, the election has been treated as an election without traverse (MPEP § 818.03(a)). Claims 1-8, 10, 12-18, 20 are withdrawn from further consideration pursuant to 37 CFR 1.142(b), as being drawn to a nonelected invention. The requirement is still deemed proper and is therefore made FINAL. Claims 22-24 are under consideration in this Office Action. Claim Objection Claim 22 is objected to since the claim depends from nonelected claim 1. Applicant is required to amend the claim to recite the method steps of claim 1. Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102 of this title, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. Claims 22-24 are rejected under 35 U.S.C. 103 as being unpatentable over WO2013067305 (05/10/2013; IDS filed 09/13/2022) in view of WO2007052081 (05/10/2007; IDS filed 09/13/2022), Rosario et al. (Continuous-Flow Fermentation of Banana Fruit Pulp Sugar into Ethanol by Carrageenan-Immobilized Yeast, Biotechnology Letters, vol. 7, no. 11, 1985, pages 819-820; IDS filed 09/13/2022). WO2013067305 (05/10/2013; IDS filed 09/13/2022) teaches a process for producing a supplement comprising banana plant extract for promoting the growth of yeasts. It was shown that the addition of the specific banana plant extract facilitates yeast growth in different growth media. In Example 9, Saccharomyces cerevisiae was hydrated and "Baclyte" was added, and the mixture was incubated at 30°C and analyzed after predetermined intervals (eg. between 30 minutes and 8 hours). See entire publication and claims especially claims 1-27 and Figs. 11 and 12. The teachings of the reference differ from the claims in that the reference does not teach the claimed method steps to allow fermentation of the sugar source to ethanol. WO2007052081 teaches a method of promoting growth of Gram positive bacteria, the method comprising providing bacteria with an extract obtainable from or obtained from Bananas (Musa spp). WO2007052081 teaches the following in the claims: 1. A method of promoting growth of Gram positive bacteria, the method comprising providing bacteria with an extract obtainable from or obtained from Musa spp. 2. The method of claim 1 wherein the extract is obtainable or obtained from bananas. 3. The method of claim 1 or claim 2 wherein the extract is obtainable from or obtained from the skin of the fruit of Musa spp. 4. The method of claims 1 or claim 2 wherein the extract is obtainable from or obtained from the pulp of the fruit of Musa spp. 5. The method of any preceding claim wherein the extract does not substantially comprise catecholamines, and/or fructo-oligosaccharides. 6. The method of any preceding claim wherein the bacteria are lactic acid bacteria. 7. The method of any preceding claim wherein the bacteria are environmentally stressed prior to growth with the extract. 8. The method of any preceding claim comprising the step of growing the bacteria in a non-anaerobic environment. 9. A method of promoting growth of environmentally stressed Gram negative bacteria, the method comprising providing bacteria with an extract obtainable from or obtained from Musa spp. 10. The method of claim 9 wherein the bacteria comprise pathogenic and/or enteric bacteria. 11. A method of promoting growth of environmentally stressed bacteria, the method comprising providing bacteria with an extract obtainable from or obtained from Musa spp. 12. A bacterial growth medium comprising an extract obtainable from or obtained from Musa spp. 13. The medium of claim 12 comprising minimal additional components. 14. The medium of claim 12 or 13 wherein the extract is present in the medium at a concentration of between 0.01 to 10%. 15. The medium of claim 14 wherein the extract is present at a concentration of 0.5 to 2%. 16. The medium of any of claims 12 to 15, for growth of Gram positive bacteria. 17. The medium of claim 16, for growth of lactic acid bacteria. 18. A bacterial growth supplement comprising an extract obtainable from or obtained from Musa spp. 19. The supplement of claim 18, formulated for addition to growth medium. Rosario et al. teaches a method for producing ethanol in the presence of extracted juice of ripe Cavendish banana fruit pulp by yeast where the yeast beads were treated with the banana extract and used for fermentation (see entire publication and abstract especially Materials and Methods section, Results and Discussion section, and pages 819-20). Therefore, it would have been obvious to one of ordinary skill in the art before the effective filing date of the claimed invention to modify and/or combine the reference teachings to make the claimed invention by modifying the method of WO2013067305 to include the method steps of WO2007052081 and Rosario et al. for ethanol fermentation using banana extract treated yeast at the recited temperature and fermentation conditions. One of ordinary skill in the art before the effective filing date of the claimed invention would have been motivated to do this in order to obtain a simple fermentation method for producing ethanol from a carbon source. It would have been obvious to adjust the fermentation temperature and use any sugar source such as potato, molasses, grain, and sugar cane as routine experimentation or as desired. One of ordinary skill in the art before the effective filing date of the claimed invention would have a reasonable expectation of success in view of the reference teachings showing growth with an extract obtainable from or obtained from Bananas. Hence, the claimed invention as a whole is prima facie obvious. Conclusion No claim is allowed. Any inquiry concerning this communication or earlier communications from the examiner should be directed to Christian L Fronda whose telephone number is (571)272 0929. The examiner can normally be reached Monday-Thursday and alternate Fridays between 9:00AM-5:00PM. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Robert Mondesi can be reached on (408)918-7584. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /CHRISTIAN L FRONDA/Primary Examiner, Art Unit 1652
Read full office action

Prosecution Timeline

Sep 13, 2022
Application Filed
Oct 22, 2025
Non-Final Rejection mailed — §103
Feb 23, 2026
Response Filed

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12637680
RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE
4y 3m to grant Granted May 26, 2026
Patent 12618087
Thraustochytrid strain genetically engineered for the production of biomaterials including docosahexaenoic acid
3y 3m to grant Granted May 05, 2026
Patent 12612591
INTEGRATED SYSTEM FOR BIOCATALYTICALLY PRODUCING AND RECOVERING AN ORGANIC SUBSTANCE
4y 3m to grant Granted Apr 28, 2026
Patent 12600991
GENETICALLY MODIFIED MICROORGANISM FOR PRODUCTION OF ASPARTIC ACID AND DOWNSTREAM METABOLITES FROM ASPARTIC ACID AS TARGET SUBSTANCE, AND METHOD FOR PRODUCING TARGET SUBSTANCE USING SAME
4y 5m to grant Granted Apr 14, 2026
Patent 12584097
FOAM CONTROL AGENTS FOR FERMENTATION
3y 3m to grant Granted Mar 24, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.
Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

1-2
Expected OA Rounds
82%
Grant Probability
96%
With Interview (+14.1%)
2y 5m (~0m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1339 resolved cases by this examiner. Grant probability derived from career allowance rate.

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month