Last updated: September 19, 2026

Application No. 17/917,992

NON-HUMAN ANIMAL SECRETOME MODELS

Final Rejection

Filed

Oct 10, 2022

Priority

Apr 21, 2020 — provisional 63/013,453 +1 more

Examiner

BEHARRY, ZANNA MARIA

Art Unit

1632

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

University of Pittsburgh

OA Round

4 (Final)

This examiner grants 25% of cases after interview

— +56.4% interview lift. A telephonic interview to clarify the technical implementation could significantly improve the outcome.

Based on 73 resolved cases, 2023–2026

Examiner Intelligence

BEHARRY, ZANNA MARIA View full profile →

Grants only 25% of cases

Career Allowance Rate

18 granted / 73 resolved

-35.3% vs TC avg

Strong +56% interview lift

Without

With

+56.4%

Interview Lift

resolved cases with interview

Typical timeline

4y 1m

Avg Prosecution

49 currently pending

Career history

148

Total Applications

across all art units

Statute-Specific Performance

§101

5.6%

-34.4% vs TC avg

§103

45.3%

+5.3% vs TC avg

§102

13.8%

-26.2% vs TC avg

§112

24.6%

-15.4% vs TC avg

Black line = Tech Center average estimate • Based on career data from 73 resolved cases

Prosecution Timeline

Show 1 earlier event

Aug 27, 2025

Non-Final Rejection mailed

Oct 01, 2025

Response Filed

Nov 28, 2025

Final Rejection mailed

Feb 09, 2026

Request for Continued Examination

Feb 11, 2026

Response after Non-Final Action

Apr 02, 2026

Non-Final Rejection mailed

Jun 22, 2026

Response Filed

Aug 18, 2026

Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

18/002,228

Patent 12702122

NON-HUMAN ANIMALS COMPRISING A HUMANIZED ACE2 LOCUS

3y 7m to grant Granted Aug 11, 2026

17/614,237

Patent 12668810

EXON-HUMANIZED MOUSE

4y 7m to grant Granted Jun 30, 2026

17/616,790

Patent 12667087

METHODS OF TREATMENT WITH AMINOLEVULINIC ACID SYNTHASE 2 (ALAS2) MODULATORS

4y 6m to grant Granted Jun 30, 2026

17/275,096

Patent 12653168

Complement Factor H Gene Knockout Rat as a Model of C3 Glomerulopathy

5y 3m to grant Granted Jun 16, 2026

17/472,310

Patent 12617817

Carrier Peptide Fragment and Use Thereof

4y 7m to grant Granted May 05, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

5-6

Expected OA Rounds

25%

Grant Probability

81%

With Interview (+56.4%)

4y 1m (~2m remaining)

Median Time to Grant

High

PTA Risk

Based on 73 resolved cases by this examiner. Grant probability derived from career allowance rate.