Last updated: May 29, 2026

Application No. 18/000,067

LARGE SCALE GENOME MANIPULATION

Non-Final OA

Filed

Nov 28, 2022

Priority

May 29, 2020 — provisional 63/031,822 +2 more

Examiner

DELEO, VICTORIA LYNN

Art Unit

1662

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Pioneer Hi-Bred International Inc.

OA Round

3 (Non-Final)

Interview Optional

— -39.1% interview lift. Interview lift (-39.1%) is below the 15.0% threshold. A written response is recommended.

Based on 24 resolved cases, 2023–2026

Examiner Intelligence

DELEO, VICTORIA LYNN View full profile →

Grants only 38% of cases

Career Allowance Rate

9 granted / 24 resolved

-22.5% vs TC avg

Minimal -39% lift

Without

With

+-39.1%

Interview Lift

resolved cases with interview

Typical timeline

2y 6m

Avg Prosecution

18 currently pending

Career history

Total Applications

across all art units

Statute-Specific Performance

§101

2.3%

-37.7% vs TC avg

§103

50.0%

+10.0% vs TC avg

§102

8.6%

-31.4% vs TC avg

§112

17.2%

-22.8% vs TC avg

Black line = Tech Center average estimate • Based on career data from 24 resolved cases

Prosecution Timeline

Nov 28, 2022

Application Filed

Mar 11, 2025

Non-Final Rejection mailed

Jul 11, 2025

Response Filed

Sep 08, 2025

Final Rejection mailed

Jan 08, 2026

Request for Continued Examination

Jan 13, 2026

Response after Non-Final Action

May 27, 2026

Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

18/031,159

Patent 12584117

Use of Gene Encoding Gibberellin 3Beta-Hydroxylase of Glycine Max, GmGA3ox1

2y 11m to grant Granted Mar 24, 2026

18/266,871

Patent 12577577

COMPOSITIONS AND METHODS TO INCREASE RESISTANCE TO PHYTOPHTHORA SOJAE IN SOYBEAN

2y 9m to grant Granted Mar 17, 2026

18/289,473

Patent 12545926

NUCLEIC ACID MOLECULES FOR CONFERRING INSECTICIDAL PROPERTIES IN PLANTS

2y 3m to grant Granted Feb 10, 2026

18/540,687

Patent 12522839

USE OF ZLMYB1 AND ZLMYB2 GENES FROM ZIZANIA LATIFOLIA IN INCREASING ANTHOCYANIDIN CONTENT OF RICE SEED

2y 1m to grant Granted Jan 13, 2026

18/167,878

Patent 12460220

METHOD FOR PROMOTING EXPRESSION OF FOREIGN GENE IN SOYBEAN, ARABIDOPSIS OR TOBACCO USING GENE PROMOTER pEIF1 OR pEIF1-I

2y 8m to grant Granted Nov 04, 2025

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

3-4

Expected OA Rounds

38%

Grant Probability

-2%

With Interview (-39.1%)

2y 6m (~0m remaining)

Median Time to Grant

High

PTA Risk

Based on 24 resolved cases by this examiner. Grant probability derived from career allowance rate.