Prosecution Insights
Last updated: April 19, 2026
Application No. 18/001,620

CONTAINED PRODUCTION OF PHARMACEUTICALLY PURE CRYSTALS

Non-Final OA §Other
Filed
Dec 13, 2022
Examiner
DAVIS, SHENG HAN
Art Unit
1732
Tech Center
1700 — Chemical & Materials Engineering
Assignee
Biosyn Arzneimittel GmbH
OA Round
2 (Non-Final)
66%
Grant Probability
Favorable
2-3
OA Rounds
3y 3m
To Grant
99%
With Interview

Examiner Intelligence

Grants 66% — above average
66%
Career Allow Rate
701 granted / 1064 resolved
+0.9% vs TC avg
Strong +36% interview lift
Without
With
+35.9%
Interview Lift
resolved cases with interview
Typical timeline
3y 3m
Avg Prosecution
67 currently pending
Career history
1131
Total Applications
across all art units

Statute-Specific Performance

§101
0.1%
-39.9% vs TC avg
§103
62.6%
+22.6% vs TC avg
§102
6.9%
-33.1% vs TC avg
§112
20.8%
-19.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1064 resolved cases

Office Action

§Other
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Election/Restrictions REQUIREMENT FOR UNITY OF INVENTION As provided in 37 CFR 1.475(a), a national stage application shall relate to one invention only or to a group of inventions so linked as to form a single general inventive concept (“requirement of unity of invention”). Where a group of inventions is claimed in a national stage application, the requirement of unity of invention shall be fulfilled only when there is a technical relationship among those inventions involving one or more of the same or corresponding special technical features. The expression “special technical features” shall mean those technical features that define a contribution which each of the claimed inventions, considered as a whole, makes over the prior art. The determination whether a group of inventions is so linked as to form a single general inventive concept shall be made without regard to whether the inventions are claimed in separate claims or as alternatives within a single claim. See 37 CFR 1.475(e). When Claims Are Directed to Multiple Categories of Inventions: As provided in 37 CFR 1.475 (b), a national stage application containing claims to different categories of invention will be considered to have unity of invention if the claims are drawn only to one of the following combinations of categories: (1) A product and a process specially adapted for the manufacture of said product; or (2) A product and a process of use of said product; or (3) A product, a process specially adapted for the manufacture of the said product, and a use of the said product; or (4) A process and an apparatus or means specifically designed for carrying out the said process; or (5) A product, a process specially adapted for the manufacture of the said product, and an apparatus or means specifically designed for carrying out the said process. Otherwise, unity of invention might not be present. See 37 CFR 1.475 (c). Restriction is required under 35 U.S.C. 121 and 372. This application contains the following inventions or groups of inventions which are not so linked as to form a single general inventive concept under PCT Rule 13.1. In accordance with 37 CFR 1.499, applicant is required, in reply to this action, to elect a single invention to which the claims must be restricted. Group I, claim(s) 1-8, drawn to a method. Group II, claim(s) 9-13, drawn to a device. Group III, claim(s) 14-15, drawn to a composition. Groups I and III and II lack unity of invention because even though the inventions of these groups require the technical feature of vacuuming, this technical feature is not a special technical feature as it does not make a contribution over the prior art in view of Ji (CN 210448159). Ji describes a device that performs vacuuming (title). Groups I, II and III lack unity of invention because the groups do not share the same or corresponding technical feature. In particular, the device is not limited to the method steps of Claim 1 except for the way it overlaps in the paragraph above and the product describes product by process features (Claim 14), which are not limiting on the product. The composition of invention III can be made using any process effective to make the same product and is not related to the device claims of invention II. Allowable Subject Matter Claims 1-8 are allowed pending cancelation of the non-elected claims. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to SHENG HAN DAVIS whose telephone number is (571)270-5823. The examiner can normally be reached 9-5:30. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Fung Coris can be reached at 571-270-5713. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /SHENG H DAVIS/ Primary Examiner, Art Unit 1732 March 19, 2026
Read full office action

Prosecution Timeline

Dec 13, 2022
Application Filed
Sep 24, 2025
Non-Final Rejection — §Other
Jan 16, 2026
Response Filed
Mar 19, 2026
Non-Final Rejection — §Other (current)

Precedent Cases

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Patent 12594546
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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

2-3
Expected OA Rounds
66%
Grant Probability
99%
With Interview (+35.9%)
3y 3m
Median Time to Grant
Moderate
PTA Risk
Based on 1064 resolved cases by this examiner. Grant probability derived from career allow rate.

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