Prosecution Insights
Last updated: May 29, 2026
Application No. 18/020,451

Serotonin Receptor Modulators

Final Rejection
Filed
Feb 09, 2023
Priority
Aug 19, 2020 — provisional 63/067,853 +1 more
Examiner
KUCHARCZK, JED A
Art Unit
1623
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Northeastern University
OA Round
2 (Final)
80%
Grant Probability
Favorable
3-4
OA Rounds
0m
Est. Remaining
96%
With Interview

Examiner Intelligence

Grants 80% — above average
80%
Career Allowance Rate
73 granted / 91 resolved
+20.2% vs TC avg
Strong +16% interview lift
Without
With
+15.6%
Interview Lift
resolved cases with interview
Typical timeline
2y 9m
Avg Prosecution
24 currently pending
Career history
117
Total Applications
across all art units

Statute-Specific Performance

§101
1.0%
-39.0% vs TC avg
§103
45.9%
+5.9% vs TC avg
§102
19.0%
-21.0% vs TC avg
§112
9.8%
-30.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 91 resolved cases

Prosecution Timeline

Feb 09, 2023
Application Filed
Jun 02, 2025
Response Filed
Sep 11, 2025
Non-Final Rejection mailed
Dec 11, 2025
Response Filed
Feb 03, 2026
Final Rejection (signed)
Mar 11, 2026
Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12629349
Recognition ability improving agent
5y 9m to grant Granted May 19, 2026
Patent 12630529
GCN2 MODULATOR COMPOUNDS
3y 9m to grant Granted May 19, 2026
Patent 12630533
HETEROCYCLIC COMPOUNDS USEFUL AS KCNT1 INHIBITORS
11m to grant Granted May 19, 2026
Patent 12617804
CONJUGATION-FUSED BIPOLAR REDOX-ACTIVE MOLECULE, PREPARATION METHOD, AND APPLICATION THEREOF
3y 8m to grant Granted May 05, 2026
Patent 12600710
BETA-CATENIN AND B-CELL LYMPHOMA 9 (BCL9) INHIBITORS
4y 12m to grant Granted Apr 14, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
80%
Grant Probability
96%
With Interview (+15.6%)
2y 9m (~0m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 91 resolved cases by this examiner. Grant probability derived from career allowance rate.

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