Prosecution Insights
Last updated: April 19, 2026
Application No. 18/020,451

Serotonin Receptor Modulators

Final Rejection
Filed
Feb 09, 2023
Examiner
KUCHARCZK, JED A
Art Unit
1623
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Northeastern University
OA Round
2 (Final)
80%
Grant Probability
Favorable
3-4
OA Rounds
2y 7m
To Grant
99%
With Interview

Examiner Intelligence

Grants 80% — above average
80%
Career Allow Rate
68 granted / 85 resolved
+20.0% vs TC avg
Strong +21% interview lift
Without
With
+20.9%
Interview Lift
resolved cases with interview
Typical timeline
2y 7m
Avg Prosecution
32 currently pending
Career history
117
Total Applications
across all art units

Statute-Specific Performance

§101
0.5%
-39.5% vs TC avg
§103
31.6%
-8.4% vs TC avg
§102
17.0%
-23.0% vs TC avg
§112
27.1%
-12.9% vs TC avg
Black line = Tech Center average estimate • Based on career data from 85 resolved cases

Prosecution Timeline

Feb 09, 2023
Application Filed
Jun 02, 2025
Response Filed
Aug 28, 2025
Non-Final Rejection
Dec 11, 2025
Response Filed
Feb 03, 2026
Final Rejection (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12600710
BETA-CATENIN AND B-CELL LYMPHOMA 9 (BCL9) INHIBITORS
2y 5m to grant Granted Apr 14, 2026
Patent 12599617
METHODS OF TREATING HEAD AND NECK CANCERS WITH HEMP EXTRACT
2y 5m to grant Granted Apr 14, 2026
Patent 12595253
BENZAMIDES OF PYRAZOLYLAMINO- PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF
2y 5m to grant Granted Apr 07, 2026
Patent 12577260
BIPHENYL COMPOUND AS IMMUNOMODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
2y 5m to grant Granted Mar 17, 2026
Patent 12570645
USES OF P53 X-RAY CO-CRYSTAL STRUCTURES
2y 5m to grant Granted Mar 10, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
80%
Grant Probability
99%
With Interview (+20.9%)
2y 7m
Median Time to Grant
Moderate
PTA Risk
Based on 85 resolved cases by this examiner. Grant probability derived from career allow rate.

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