Prosecution Insights
Last updated: April 19, 2026
Application No. 18/021,460

PHARMACEUTICAL COMPOSITIONS COMPRISING IONIC LIQUIDS

Non-Final OA §102§112
Filed
Feb 15, 2023
Examiner
AZPURU, CARLOS A
Art Unit
1617
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
UNIVERSITY COLLEGE DUBLIN
OA Round
1 (Non-Final)
84%
Grant Probability
Favorable
1-2
OA Rounds
2y 9m
To Grant
94%
With Interview

Examiner Intelligence

Grants 84% — above average
84%
Career Allow Rate
1067 granted / 1276 resolved
+23.6% vs TC avg
Moderate +10% lift
Without
With
+10.3%
Interview Lift
resolved cases with interview
Typical timeline
2y 9m
Avg Prosecution
23 currently pending
Career history
1299
Total Applications
across all art units

Statute-Specific Performance

§101
1.1%
-38.9% vs TC avg
§103
23.0%
-17.0% vs TC avg
§102
18.4%
-21.6% vs TC avg
§112
29.8%
-10.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1276 resolved cases

Office Action

§102 §112
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . A preliminary amendment was filed 02/25/2025. Information Disclosure Statement Information disclosure statements were filed on 02/15/2023 and 10/24/2025. Election/Restrictions Applicant’s election without traverse of Group I, claims 1-11 in the reply filed on 12/11/2025 is acknowledged. Claims 12-19 are withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to a nonelected invention, there being no allowable generic or linking claim. Election was made without traverse in the reply filed on 12/11/2025. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claims 5-7 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Claim 5 is indefinite because the metes and bounds of the claimed Markush Grouping are not proper. Overlapping terms such as polysaccharide and polysaccharide derivative are present. Further, the phrase "such as" renders the claim indefinite because it is unclear whether the limitations following the phrase are part of the claimed invention. See MPEP § 2173.05(d). Correction is requested. Claims 6 and 7 are indefinite in referring to the Biopharmaceutics Classification System. The US Patent and Trademark Office does not have labs to verify chemical characteristics. Applicant should particularly point out the specific solubility conditions of the composition. Clarification and correction are requested. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 1 and 5 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Jouannin et al. Regarding claim 1 , Jouannin et al discloses a composition comprising a polymer and a salt of a pharmaceutical compound wherein the salt is an ionic liquid, and a solid dosage form. The ionic salts include 1-butyl-3-methylimidazolium ibuprofenate (see Abstract, pages 3133- 3140). With regard to claim 5, the polymer is PLLA (Abstract). The claims are anticipated by Jouannin et al. Claim(s) 1 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Chantereau et al. Chantereau et al discloses a composition comprising a polymer and a salt of a pharmaceutical compound wherein the salt is an ionic liquid, and a solid dosage form. The ionic salts include sodium ibuprofen, sodium diclofenac and sodium naproxen ( see page 14126, bottom left column). Claim 1 is anticipated by Chantereau et al. Conclusion No claims are allowed. Claims 2-4, 8-11 are objected to as dependent upon a rejected base claim. Correspondence Any inquiry concerning this communication or earlier communications from the examiner should be directed to CARLOS A AZPURU whose telephone number is (571)272-0588. The examiner can normally be reached 9 am- 3 pm, 4 pm-8pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Sue X Liu can be reached at 571-272-5539. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /CARLOS A AZPURU/ Primary Examiner, Art Unit 1617 caz
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Prosecution Timeline

Feb 15, 2023
Application Filed
Jan 21, 2026
Non-Final Rejection — §102, §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
84%
Grant Probability
94%
With Interview (+10.3%)
2y 9m
Median Time to Grant
Low
PTA Risk
Based on 1276 resolved cases by this examiner. Grant probability derived from career allow rate.

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