Prosecution Insights
Last updated: April 19, 2026
Application No. 18/028,147

INHALATION DEVICE

Non-Final OA §103§112
Filed
Mar 23, 2023
Examiner
MURPHY, VICTORIA
Art Unit
3785
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
VECTURA DELIVERY DEVICES LIMITED
OA Round
1 (Non-Final)
62%
Grant Probability
Moderate
1-2
OA Rounds
4y 3m
To Grant
99%
With Interview

Examiner Intelligence

Grants 62% of resolved cases
62%
Career Allow Rate
179 granted / 291 resolved
-8.5% vs TC avg
Strong +47% interview lift
Without
With
+47.4%
Interview Lift
resolved cases with interview
Typical timeline
4y 3m
Avg Prosecution
28 currently pending
Career history
319
Total Applications
across all art units

Statute-Specific Performance

§101
4.3%
-35.7% vs TC avg
§103
39.2%
-0.8% vs TC avg
§102
19.2%
-20.8% vs TC avg
§112
31.5%
-8.5% vs TC avg
Black line = Tech Center average estimate • Based on career data from 291 resolved cases

Office Action

§103 §112
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claim Objections The claims are objected to because of the following informalities: The preamble of claims 2-12 should read “The device according to…” Appropriate correction is required. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claims 1-12 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Regarding claim 1, the phrase "such as" renders the claim indefinite because it is unclear whether the limitations following the phrase are part of the claimed invention. See MPEP § 2173.05(d). Based on claim 3, the examiner is interpreting the claim not to require the pumps listed after “such as”, since claim 3 re-introduces “a rolling diaphragm pump”. Claims 2-12 are rejected due to their dependencies on claim 1. Claim Rejections - 35 USC § 103 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. The factual inquiries for establishing a background for determining obviousness under 35 U.S.C. 103 are summarized as follows: 1. Determining the scope and contents of the prior art. 2. Ascertaining the differences between the prior art and the claims at issue. 3. Resolving the level of ordinary skill in the pertinent art. 4. Considering objective evidence present in the application indicating obviousness or nonobviousness. Claim(s) 1, 3-5 is/are rejected under 35 U.S.C. 103 as being unpatentable over Thompson (US 3,301,255) in view of Adahan (US 2010/0139660 A1) in further view of Mullinger et al. (US 2009/0178672 A1) Regarding claim 1, Thompson discloses: A device for providing a flow of aerosol and/or air (figure 1), comprising a base unit (portable case of 20 with boxlike body 21 and lid 22 and handle 23; col. 3, lines 31-33) containing a first pump (32) for providing a nebulizer air flow, a first channel (47) that connects the first pump to a first air outlet (48) (see figure 4), a second air source (31) for providing a support air flow, a second channel (38) that connects the second pump to a second air outlet (40), a pressure sensor (43) connected to the second channel (via 42 as shown in figures 2, 3), and a controller (34) for controlling the second pump; a handset (26) containing a reservoir (where 53 is stored in figure 5) for liquid (53) to be nebulized, a mouthpiece (29), and a mixing chamber (27) having a first air inlet (where 52 connects to 27) connected to a nebulizing nozzle for generating an aerosol flow from the nebulizer air flow and the liquid (fluidically connected as shown in figure 5), and a second air inlet (where 24 connects to 27); a first tube (25) connecting the first air outlet to the first air inlet (see figure 1); and a second tube (24) connecting the second air outlet to the second air inlet (see figure 1). Thompson does not explicitly disclose the second air source is a second pump which is a multiple head diaphragm pump, such as a rolling diaphragm pump; or a rotary vane pump; or a scroll pump nor that the controller (34) controls the first pump. However, Adahan teaches it is known to us a rolling diaphragm pump (100) as a means to provide respiration air [0025]-[0026]. Therefore it would have been obvious to one having ordinary skill in the art to have modified Thompson by substituting one known device for creating an airflow (31 of Thompson) for a rolling diaphragm pump (Adahan’s 100) since the substitution of one known element for another yields predictable results to one of ordinary skill in the art. KSR Int'l Co. v. Teleflex Inc., 550 U.S. 398, 415-421, 82 USPQ2d 1385, 1395-97 (2007) Further, Mullinger teaches it is known for a controller (260) to control flow into a nebulizer [0048]. Therefore, it would have been obvious one having ordinary skill in the art before the effective filing date of the claimed invention to have modified Thompson such that a controller controls the first pump for the benefit of allowing the delivery of medicament can be altered as needed [0048]. Regarding claim 3, Thompson as modified further discloses wherein the second pump is a rolling diaphragm pump (Adahan’s 100). Regarding claim 4, Thompson as modified discloses the claimed invention substantially as claimed as set forth above. The currently modified Thompson does not explicitly disclose a display screen for providing instructions and / or feedback. However, Adahan further discloses it is known to provide a display screen (270) for providing instructions and / or feedback [0047]. Therefore it would have been obvious to one having ordinary skill in the art to include a display screen for providing instructions and / or feedback as taught by Adahan for providing important information to the user. Regarding claim 5, Thompson as modified discloses the invention essentially as claimed as discussed above. However, Thompson does not expressly disclose wherein the first and / or second tubes are from 1000 mm to 1300 mm in length and have an inner diameter of from 3 to 5 mm. It would have been obvious to one having ordinary skill in the art before the effective filing date of the claimed invention to cause the device of Thompson to have wherein the first and / or second tubes are from 1000 mm to 1300 mm in length and have an inner diameter of from 3 to 5 mm since it has been held that “where the only difference between the prior art and the claims was a recitation of relative dimensions of the claimed device and a device having the claimed relative dimensions would not perform differently than the prior art device, the claimed device was not patentably distinct from the prior art device” Gardner v. TEC Syst., Inc., 725 F.2d 1338, 220 USPQ 777 (Fed. Cir. 1984), cert. denied, 469 U.S. 830, 225 SPQ 232 (1984). In the instant case, the device of Thompson would not operate differently with the claimed dimensions and since Thompson already has tubing the device would function appropriately having the claimed dimensions Further, applicant places no criticality on the range claimed. Claim(s) 6-12 is/are rejected under 35 U.S.C. 103 as being unpatentable over Thompson (US 3,301,255) in view of Adahan (US 2010/0139660 A1) in further view of Mullinger et al. (US 2009/0178672 A1) in further view of Luber et al. (WO 2010/097119) Regarding claim 6, Thompson as modified discloses the invention essentially as claimed as discussed above. Thompson does not expressly disclose wherein the device is configured to provide, during an inhalation by the patient, an aerosol period in which there is both support flow and aerosol flow so that aerosol is delivered to the patient, and one or more aerosol- free periods when there is support flow but no aerosol flow, so that only air is delivered to the patient. However, Luber discloses a device utilizing a jet nebulizer (similar to Thompson; see page 7, lines 3-5 of Luber) comprising a support flow (flow 2 of figure 6) and an aerosol flow (flow 1 of figure 6), wherein the device is configured to provide, during an inhalation by the patient, an aerosol period in which there is both support flow and aerosol flow so that aerosol is delivered to the patient (see figure 6 where flow 1 and 2 overlap; page 31, paragraph 3), and one or more aerosol- free periods when there is support flow but no aerosol flow, so that only air is delivered to the patient (see figure 6, after aerosol flow finishes only air is delivered via flow 2; page 31, paragraph 3). It would have been obvious to one having ordinary skill in the art before the effective filing date of the claimed invention to have modified Thompson such that the device is configured to provide, during an inhalation by the patient, an aerosol period in which there is both support flow and aerosol flow so that aerosol is delivered to the patient, and one or more aerosol- free periods when there is support flow but no aerosol flow, so that only air is delivered to the patient to minimize waste and also ensure the medicament is delivered to the desired location (page 33, paragraph 1). Regarding claim 7, Thompson as modified discloses the invention essentially as claimed as discussed above. Thompson as modified by Luber further discloses wherein in each inhalation an aerosol period followed by an aerosol-free period is provided (figure 6 of Luber). Regarding claim 8, Thompson as modified discloses the invention essentially as claimed as discussed above. Thompson as modified is not explicit in that the device is configured to increase the support flow rate during the aerosol-free period(s) so that the total flow rate is approximately constant throughout the inhalation. However, Luber discloses the support flow rate (second flow rate) as well as the aerosol flow rate (first flow rate) as results effective in that they can be optimized in order to achieve optimal aerosol generation and transport (page 6, paragraph 3). Therefore, it would have been obvious to one having ordinary skill in the art at the time of the invention to modify the device of Thompson so that the device is configured to increase the support flow rate during the aerosol-free period(s) so that the total flow rate is approximately constant throughout the inhalation as a matter of routine optimization since it has been held that “where the general conditions of a claim are disclosed in the prior art, it is not inventive to discover the optimum or workable ranges by routine experimentation." In re Aller, 220 F.2d 454, 456, 105 USPQ 233, 235 (CCPA 1955). Regarding claim 9, Thompson as modified discloses the invention essentially as claimed as discussed above. Thompson as modified by Luber further discloses the device which is configured to vary the support flow rate so that the total flow rate mimics the patient's natural breathing pattern (Luber: see figure 6 shows that support flow 2 is turned on and off; claim 33 indicates vibration only occurs during exhalation). Regarding claim 10, Thompson as modified discloses the invention essentially as claimed as discussed above. Thompson as modified by Luber discloses that the initiation of support flow (flow 2) is dependent on aerosol generation flow (see figure 6), but does not explicitly describe that aerosol generation flow is dependent on a breathing pattern of the patient. Therefore, currently Thompson as modified does not explicitly disclose that the device is does not explicitly describe the device is configured to vary the support flow rate in response to the patient's inhalation rate. However, Mullinger further teaches that it is known to time aerosol administration with the patient’s inhalation/exhalation [0005] [0010] [0038]. Therefore, it would have been obvious to have modified Thompson such that aerosol administration is initiated upon inspiration so that aerosol is not wasted. With this modification, the support flow would also be varied in response to the patient’s inhalation rate. Regarding claim 11, Thompson as modified discloses the invention essentially as claimed as discussed above. Thompson as modified by Luber further discloses the device which is configured to pulse the support flow (Luber: figure 6). Regarding claim 12, Thompson as modified discloses the invention essentially as claimed as discussed above. Thompson as modified by Luber further discloses the device configured to provide feedback to the patient through the support flow. However, Luber discloses the support flow rate (second flow rate) can be higher than the first flow rate. It would have been obvious one having ordinary skill in the art to have modified Thompson such that the second flow rate is higher than the first flow rate in order to optimize transportation (page 6, paragraph 3). This increased flow is configured to provide feedback to the patient through the support flow. For example, this increased flow would indicate to the user that aerosol transportation is occurring. Claim(s) 2 is/are rejected under 35 U.S.C. 103 as being unpatentable over Thompson (US 3,301,255) in view of Adahan (US 2010/0139660 A1) in further view of Mullinger et al. (US 2009/0178672 A1) in further view Zambon et al. (US 2008/0078381 A1). Regarding claim 2, Thompson as modified discloses the claimed invention as claimed as set forth for claim 1 above. Thompson does not explicitly disclose wherein the first pump (32) is a piston-type compressor. However, Zambon teaches it is known for nebulizers of a pneumatic type to be run by piston compressors [0005]. Therefore it would have been obvious to one having ordinary skill in the art to have modified Thompson by substituting one known device for creating an airflow (32 of Thompson) for a piston type compressor (as taught by Zambon [0005]) since the substitution of one known element for another yields predictable results to one of ordinary skill in the art. KSR Int'l Co. v. Teleflex Inc., 550 U.S. 398, 415-421, 82 USPQ2d 1385, 1395-97 (2007). Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to VICTORIA MURPHY whose telephone number is (571)270-7362. The examiner can normally be reached M-F 8:00am-4:00pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Kendra Carter can be reached at (571) 272-9034. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /VICTORIA MURPHY/Primary Patent Examiner, Art Unit 3785
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Prosecution Timeline

Mar 23, 2023
Application Filed
Nov 20, 2025
Non-Final Rejection — §103, §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
62%
Grant Probability
99%
With Interview (+47.4%)
4y 3m
Median Time to Grant
Low
PTA Risk
Based on 291 resolved cases by this examiner. Grant probability derived from career allow rate.

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