Prosecution Insights
Last updated: April 19, 2026
Application No. 18/029,899

COMPOUNDS WITH GLUCOCORTICOID SPARING EFFECTS AND USES THEREOF

Non-Final OA §102
Filed
Mar 31, 2023
Examiner
MOORE, SUSANNA
Art Unit
1624
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
The Regents of the University of California
OA Round
1 (Non-Final)
68%
Grant Probability
Favorable
1-2
OA Rounds
3y 0m
To Grant
99%
With Interview

Examiner Intelligence

Grants 68% — above average
68%
Career Allow Rate
842 granted / 1237 resolved
+8.1% vs TC avg
Strong +32% interview lift
Without
With
+32.2%
Interview Lift
resolved cases with interview
Typical timeline
3y 0m
Avg Prosecution
68 currently pending
Career history
1305
Total Applications
across all art units

Statute-Specific Performance

§101
1.4%
-38.6% vs TC avg
§103
18.6%
-21.4% vs TC avg
§102
17.3%
-22.7% vs TC avg
§112
36.6%
-3.4% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1237 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . This is the first action on the merits. Election/Restrictions Applicant’s election of Group (I) in the reply filed on October 27, 2025 is acknowledged. Because applicant did not distinctly and specifically point out the supposed errors in the restriction requirement, the election has been treated as an election without traverse (MPEP § 818.01(a)). Group I, drawn to compounds of formula (I), pyrazolo[3,4-d]pyrimidines, and compositions thereof, embraced by claims 1, 2, 5, 7 and 17 was elected by Applicant. Applicant has not pointed to any errors in the Examiner’s analysis of the different inventions. The requirement is still deemed proper and is therefore made FINAL. Applicant elected the following species: PNG media_image1.png 97 380 media_image1.png Greyscale The Examiner agreed in an interview on October 24, 2025, to an election of the narrowest species possible based on the description in the specification since Applicant noted there were no specific compounds disclosed. Applicant’s election is not the narrowest available. However, to move forth with prosecution, the species election will start with the first definition elected above for each R group, i.e. R1= C6-C10 aryl, R2= (C1-C3)-alkyl and R3 and R4= H, which are embraced by claims 1, 5, 7 and 17. Claims 1, 2, 5, 7, 13, 14, 16-19, 21-23, 26, 28, 32, 33, 35, 36 and 38 are pending. Claims 1, 5, 7 and 17 are under examination and claims 2, 13, 14, 16, 18, 19, 21-23, 26, 28, 32, 33, 35, 36 and 38 are withdrawn based on the species election and restriction requirement. Information Disclosure Statement A portion of the IDS submitted on July 21, 2025 was not considered since the applications were not properly cited. 37 CFR 1.98 states, “(2) Each U.S. patent application publication listed in an information disclosure statement shall be identified by applicant, patent application publication number, and publication date. (3) Each U.S. application listed in an information disclosure statement must be identified by the inventor, application number, and filing date.” Furthermore, all documents should have a publication date, mail date for foreign documents or a retrieval date with the web address from the internet if no other date is provided. Moreover, Applicant has an obligation to call the most pertinent prior art to the attention of the U.S. Patent and Trademark Office in a proper fashion. Burying one reference in one hundred other IDS references is like citing nothing. PENN YAN BOATS, INC. v. SEA LARK BOATS, INC. 175 USPQ 260 (S.D. Fla. 1972). Golden Valley Microwave Foods, Inc. v. Weaver Popcorn Co. Inc., 24 USPQ2d 1801 (U.S. Dist. N. Dist. IN 1992). In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale or otherwise available to the public before the effective filing date of the claimed invention. (a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention. Claim(s) 1, 5, 7 and 17 are rejected under 35 U.S.C. 102(a)(1) and 102(a)(2) as being anticipated by or, in the alternative, under 35 U.S.C. 103 as obvious over Minor et al. (US 20160031814). The reference teaches the following species: PNG media_image2.png 233 509 media_image2.png Greyscale , see page 91, Table 5, compound ML45. The disclosure teaches alkyl as substituted and unsubstituted, see pages 14-15. The compound was assayed in DMSO, a pharmaceutically acceptable excipient, see Figure 1. Thus, said claims are anticipated. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to SUSANNA MOORE whose telephone number is (571)272-9046. The examiner can normally be reached Monday - Friday, 10:00 am to 7:00 pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Jeffrey Murray can be reached on 571-272-9023. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /SUSANNA MOORE/Primary Examiner, Art Unit 1624
Read full office action

Prosecution Timeline

Mar 31, 2023
Application Filed
Oct 24, 2025
Examiner Interview Summary
Oct 24, 2025
Applicant Interview (Telephonic)
Nov 15, 2025
Non-Final Rejection — §102 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
68%
Grant Probability
99%
With Interview (+32.2%)
3y 0m
Median Time to Grant
Low
PTA Risk
Based on 1237 resolved cases by this examiner. Grant probability derived from career allow rate.

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