Last updated: May 29, 2026

Application No. 18/031,077

PIPERIDINYL SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE

Final Rejection

Filed

Apr 10, 2023

Priority

Oct 16, 2020 — provisional 63/092,610 +2 more

Examiner

TOWNSLEY, SARA ELIZABETH

Art Unit

1629

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Neomorph Inc.

OA Round

2 (Final)

This examiner grants 25% of cases after interview

— +48.6% interview lift. A telephonic interview to clarify the technical implementation could significantly improve the outcome.

Based on 383 resolved cases, 2023–2026

Examiner Intelligence

TOWNSLEY, SARA ELIZABETH View full profile →

Grants only 25% of cases

Career Allowance Rate

97 granted / 383 resolved

-34.7% vs TC avg

Strong +49% interview lift

Without

With

+48.6%

Interview Lift

resolved cases with interview

Typical timeline

4y 0m

Avg Prosecution

47 currently pending

Career history

438

Total Applications

across all art units

Statute-Specific Performance

§101

0.4%

-39.6% vs TC avg

§103

59.6%

+19.6% vs TC avg

§102

12.1%

-27.9% vs TC avg

§112

10.3%

-29.7% vs TC avg

Black line = Tech Center average estimate • Based on career data from 383 resolved cases

Prosecution Timeline

Apr 10, 2023

Application Filed

Aug 12, 2025

Non-Final Rejection mailed

Dec 12, 2025

Response Filed

Mar 10, 2026

Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

18/030,785

Patent 12637459

SOLID STATE FORMS OF LORECIVIVINT

3y 1m to grant Granted May 26, 2026

17/916,405

Patent 12624028

1H-PYRAZOLO[4,3-G]ISOQUINOLINE AND 1H-PYRAZOLO[4,3-G]QUINOLINE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)

3y 7m to grant Granted May 12, 2026

17/995,602

Patent 12605364

METHODS OF TREATING SARS-COV-2 INFECTIONS

3y 6m to grant Granted Apr 21, 2026

18/023,920

Patent 12600738

QUINOLINONE DERIVATIVE COMPOUND SELECTIVELY BINDING TO CYSTEINE, PEPTIDE CONJUGATE THEREOF, AND ANTIBODY-DRUG CONJUGATE COMPRISING SAME

3y 1m to grant Granted Apr 14, 2026

17/995,604

Patent 12582633

METHODS OF TREATING SEVERE ACUTE RESPIRATORY SYNDROME

3y 5m to grant Granted Mar 24, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

3-4

Expected OA Rounds

25%

Grant Probability

74%

With Interview (+48.6%)

4y 0m (~10m remaining)

Median Time to Grant

Moderate

PTA Risk

Based on 383 resolved cases by this examiner. Grant probability derived from career allowance rate.