Last updated: April 24, 2026

Application No. 18/033,049

Untitled Application

Unknown

Filed

1600

Examiner

ARIETI, RUTH SOPHIA

Art Unit

1635

Tech Center

Duke University

Assignee

Duke University

OA Round

1 (Non-Final)

This examiner grants 46% of cases after interview

— +72.7% interview lift. A telephonic interview to clarify the technical implementation could significantly improve the outcome.

Based on 81 resolved cases, 2023–2026

Examiner Intelligence

ARIETI, RUTH SOPHIA View full profile →

Grants 46% of resolved cases

Career Allow Rate

37 granted / 81 resolved

-14.3% vs TC avg

Strong +73% interview lift

Without

With

+72.7%

Interview Lift

resolved cases with interview

Typical timeline

2y 7m

Avg Prosecution

37 currently pending

Career history

118

Total Applications

across all art units

Statute-Specific Performance

§101

5.0%

-35.0% vs TC avg

§103

30.4%

-9.6% vs TC avg

§102

12.3%

-27.7% vs TC avg

§112

29.2%

-10.8% vs TC avg

Black line = Tech Center average estimate • Based on career data from 81 resolved cases

Prosecution Timeline

1600

Application Filed

Precedent Cases

Applications granted by this same examiner with similar technology

18/516,722

Patent 12594349

COMPOSITIONS AND METHODS FOR THE TARGETING OF PCSK9

2y 5m to grant Granted Apr 07, 2026

18/976,043

Patent 12584134

COMPOSITION FOR REGULATING PRODUCTION OF INTERFERING RIBONUCLEIC ACID

2y 5m to grant Granted Mar 24, 2026

18/582,317

Patent 12540324

COMPOSITION FOR REGULATING PRODUCTION OF INTERFERING RIBONUCLEIC ACID

2y 5m to grant Granted Feb 03, 2026

18/932,078

Patent 12540326

COMPOSITION FOR REGULATING PRODUCTION OF INTERFERING RIBONUCLEIC ACID

2y 5m to grant Granted Feb 03, 2026

17/275,959

Patent 12534728

RNAi Agents for Inhibiting Expression of 17beta-HSD Type 13 (HSD17B13), Compositions Thereof, and Methods of Use

2y 5m to grant Granted Jan 27, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

AI Strategy Recommendation

Get an AI-powered prosecution strategy using examiner precedents, rejection analysis, and claim mapping.

Prosecution Projections

1-2

Expected OA Rounds

46%

Grant Probability

99%

With Interview (+72.7%)

2y 7m

Median Time to Grant

Low

PTA Risk

Based on 81 resolved cases by this examiner. Grant probability derived from career allow rate.

Untitled Application

This examiner grants 46% of cases after interview

Examiner Intelligence

Statute-Specific Performance

Prosecution Timeline

Precedent Cases

Applications granted by this same examiner with similar technology

AI Strategy Recommendation

Prosecution Projections

Ready to respond to this office action?

Sign in with your work email