Office Action Predictor
Application No. 18/035,782

HEART VALVE ABLATION CATHETER

Non-Final OA §102
Filed
May 08, 2023
Examiner
CLARK, RYAN T
Art Unit
3794
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Bio Refine LTD.
OA Round
1 (Non-Final)
50%
Grant Probability
Moderate
1-2
OA Rounds
4y 1m
To Grant
93%
With Interview

Examiner Intelligence

50%
Career Allow Rate
131 granted / 263 resolved
Without
With
+42.8%
Interview Lift
avg trend
4y 1m
Avg Prosecution
35 pending
298
Total Applications
career history

Statute-Specific Performance

§101
0.7%
-39.3% vs TC avg
§103
51.7%
+11.7% vs TC avg
§102
25.2%
-14.8% vs TC avg
§112
13.8%
-26.2% vs TC avg
Black line = Tech Center average estimate • Based on career data

Office Action

§102
DETAILED ACTION A complete action on the merits of pending claims 1, 6, 7, 11, 17, 18, 24, 26, 27, 29, and 49-54 appears below. Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. Election/Restrictions Claims 32-36, 40, and 46-48 withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to a nonelected device, there being no allowable generic or linking claim. Election was made without traverse in the reply filed on 7/9/25. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale or otherwise available to the public before the effective filing date of the claimed invention. (a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention. Claims 1, 6, 7, 11, 17, 18, 24, 26, 27, 29, and 49-54 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Gifford US 20200275974. Regarding claims 1 and 24, Gifford teaches piercing tissue along a perimeter of a heart valve with at least one electrode (Fig. 4D); applying mechanical force to the at least one electrode to deform the pierced tissue and reduce the perimeter of the heart valve annulus (par. [0077] pushing tissue together or par. [0081] walked method of turning one electrode in place to place the second); delivering tissue-ablating energy through the electrode, thereby inducing plastic deformation of the deformed tissue (par. [0078]); and releasing the mechanical force, leaving the heart valve annulus with a reduced perimeter (par. [0071]); wherein the applying mechanical force comprises placing torsion on the pierced tissue (par. [0077] pushing tissue together or par. [0081] walked method of turning one electrode in place to place the second). Regarding claim 6, Gifford teaches wherein the at least one sharpened element also comprises an element is used to deliver the structurally disruptive energy to the tissue (par. [0078]). Regarding claim 7, Gifford teaches wherein the at least one sharpened element delivers the structurally disruptive energy to the tissue by operating as an electrode (par. [0078]). Regarding claim 11, Gifford teaches wherein the mechanical deforming comprises compression including pinching the tissue between a plurality of the at least one sharpened element (par. [0077] pushing tissue together). Regarding claim 17, Gifford teaches wherein the tissue-ablating energy is provided by at least one of the group consisting of: radiofrequency energy; focused ultrasound energy; cryogenic cooling (par. [0078]). Regarding claim 18, Gifford teaches wherein the tissue ablated comprises at least one of the group consisting of: fibrous tissue of the valve annulus; and tissue of the heart wall adjacent to the fibrous tissue of the valve annulus (par. [0070]). Regarding claim 26, Gifford teaches wherein the applying mechanical force comprises compressing the pierced tissue (par. [0077] pushing tissue together). Regarding claim 27, Gifford teaches wherein the tissue-ablating energy is radiofrequency energy (par. [0078]). Regarding claim 29, Gifford teaches wherein the reduced perimeter draws leaflets of the heart valve into positions that reduce regurgitation of the valve (par. [0069]). Regarding claim 49, Gifford teaches wherein the at least one sharpened element comprises a plurality of sharpened elements (Fig. 4D), and the tissue is compressed by the torsion without change in distance between any of the plurality of sharpened elements (par. [0081] walked method of turning one electrode in place to place the second). Regarding claim 50, Gifford teaches comprising measuring impedance using the at least one sharpened element, and adjusting one or more of the delivery energy and operations to perform the piercing, using the measured impedance (par. [0075]). Regarding claim 51, Gifford teaches wherein the piercing the tissue comprises: placing a casing containing the at least one sharpened element in contact with the tissue (Fig. 1 108a/108b); and extending the at least one sharpened element out of the casing and into the tissue (par. [0073]). Regarding claim 52, Gifford teaches wherein the at least one sharpened element comprises a plurality of sharpened elements extending from the casing parallel to each other (Figs. 2 and 3). Regarding claim 53, Gifford teaches wherein a depth of the piercing of the tissue is limited by a distal surface of the casing (Fig. 4C 108 distal end against tissue). Regarding claim 54, Gifford teaches wherein the energy delivered comprises at least 112 Joules delivered over a period of at least 12 seconds (Watts=Joules/second and par. [0078] the heating can be done for about 15 seconds, the wattage can be between 10 and 100 Watts). Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to RYAN T. CLARK whose telephone number is (408)918-7606. The examiner can normally be reached on Monday-Friday 7AM-3PM MT. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Linda Dvorak can be reached on (571)272-4764. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of an application may be obtained from the Patent Application Information Retrieval (PAIR) system. Status information for published applications may be obtained from either Private PAIR or Public PAIR. Status information for unpublished applications is available through Private PAIR only. For more information about the PAIR system, see http://pair-direct.uspto.gov. Should you have questions on access to the Private PAIR system, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative or access to the automated information system, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /R.T.C./Examiner, Art Unit 3794 /LINDA C DVORAK/Primary Examiner, Art Unit 3794
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Prosecution Timeline

May 08, 2023
Application Filed
Dec 27, 2025
Non-Final Rejection — §102
Mar 27, 2026
Response Filed

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Prosecution Projections

1-2
Expected OA Rounds
50%
Grant Probability
93%
With Interview (+42.8%)
4y 1m
Median Time to Grant
Low
PTA Risk
Based on 263 resolved cases by this examiner