DETAILED ACTION
Notice of Pre-AIA or AIA Status
The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA .
Applicant’s arguments and amendments filed on 5/4/2026 have been entered.
Claims 1, 3, 4, 6, 8, 10 and 12 have been amended.
Claims 40 and 41 are new.
In view of Applicant’s amendments to the claims, the 112b rejections are withdrawn.
In view of Applicant’s amendments to claim 1, the ODP, 102 and 103 are withdrawn. However, the new amendment would necessitate a new rejection under New Matter below.
Claims 1, 3-5, 6, 8, 10-12, 40 and 41 are examined in the instant application.
Claim Rejections - 35 USC § 112
The following is a quotation of the first paragraph of 35 U.S.C. 112(a):
(a) IN GENERAL.—The specification shall contain a written description of the invention, and of the manner and process of making and using it, in such full, clear, concise, and exact terms as to enable any person skilled in the art to which it pertains, or with which it is most nearly connected, to make and use the same, and shall set forth the best mode contemplated by the inventor or joint inventor of carrying out the invention.
The following is a quotation of the first paragraph of pre-AIA 35 U.S.C. 112:
The specification shall contain a written description of the invention, and of the manner and process of making and using it, in such full, clear, concise, and exact terms as to enable any person skilled in the art to which it pertains, or with which it is most nearly connected, to make and use the same, and shall set forth the best mode contemplated by the inventor of carrying out his invention.
Claims 1, 3-5, 6, 8, 10-12, 40 and 41 are rejected under 35 U.S.C. 112(a) or 35 U.S.C. 112 (pre-AIA ), first paragraph, as failing to comply with the written description requirement. The claim(s) contains subject matter which was not described in the specification in such a way as to reasonably convey to one skilled in the relevant art that the inventor or a joint inventor, or for applications subject to pre-AIA 35 U.S.C. 112, the inventor(s), at the time the application was filed, had possession of the claimed invention. This is a new matter rejection.
Applicants have amended claim 1 to recite that the culture medium is further supplemented with components group consisting of L-ascorbic acid or a derivative thereof, an activator of JAK/STAT3 signaling, an inhibitor of MAPK/ERK signaling and a tankyrase inhibitor. However, a review of the instant specification and originally filed claims provides no support for a culture medium that comprises a basal medium, an HDAC inhibitor and one or more of a PRC and EZH2 inhibitor and consists of a components group consisting of L-ascorbic acid or a derivative thereof, an activator of JAK/STAT3 signaling, an inhibitor of MAPK/ERK signaling and a tankyrase inhibitor. There is no teaching in the specification regarding a culture medium comprising the 3-4 components and consisting of the four components set forth in amended claim 1.
If Applicant believes this rejection is in error they are invited to cite line and page number where the amended culture medium can be found in the specification.
Conclusion
No claims are allowed.
Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a).
A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action.
Any inquiry concerning this communication or earlier communications from the examiner should be directed to DAVID A MONTANARI whose telephone number is (571)272-3108. The examiner can normally be reached M-Tr 8-6.
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DAVID A. MONTANARI
Examiner
Art Unit 1632
/ANOOP K SINGH/Primary Examiner, Art Unit 1632
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