DETAILED ACTION
Notice of Pre-AIA or AIA Status
1. The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA .
Election/Restrictions
2. Applicant’s election without traverse of Group I (claims 1 and 2) and species (methods): b. treating human cancers in claim 10 and 14-21 in the reply filed on March 30, 2026 is acknowledged.
However, the elected the Group does not read on the species. Hence, the species election will be held in abeyance until the Groups V-VIII are rejoined and/or examined on the merits.
3. Claims 1-21 are pending.
Claims 3-21, drawn on non-elected inventions are examined on the merits.
Claims 3 and 6-10 have been amended.
Claims 11-21 have been added.
Claims 1 and 2 are examined on the merits.
Claim Rejections - 35 USC § 102
6. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action:
A person shall be entitled to a patent unless –
(a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention.
7. Claim(s) 1 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Hedlund et al., US 2006/0057111 A1 (published March 16, 2006/ IDS reference #1, U.S. Patent Application Publications submitted August 21, 2024). Hedlund discloses a humanized antibody, which is the same as Applicant’s comprising the same heavy chain variable region and light chain variable region, see sequence listing below. Moreover, Applicant’s heavy chain variable region, SEQ ID NO: 8 is at least 90% to Hedlund’s sequences, sequence 5 and sequence 11.
RESULT 17 from 1fus2fus3.align.rapbm database.
US-11-202-507A-11
(NOTE: this sequence has 1 duplicate in the database searched.
See complete list at the end of this report)
Sequence 11, US/11202507A
Publication No. US20060057111A1
GENERAL INFORMATION
APPLICANT: Hedlund, Gunnar
APPLICANT: Forsberg, Goran
APPLICANT: Wallen-Ohman, Marie
TITLE OF INVENTION: TREATMENT OF HYPERPROLIFERATIVE DISEASE WITH SUPERANTIGENS IN
TITLE OF INVENTION: COMBINATION WITH ANOTHER ANTICANCER AGENT
FILE REFERENCE: P03024US1
CURRENT APPLICATION NUMBER: US/11/202,507A
CURRENT FILING DATE: 2005-08-12
PRIOR APPLICATION NUMBER: US 60/601,548
PRIOR FILING DATE: 2004-08-13
NUMBER OF SEQ ID NOS: 16
SEQ ID NO 11
LENGTH: 678
TYPE: PRT
ORGANISM: Staphylococcus sp
Query Match 87.9%; Score 178.4; Length 678;
Best Local Similarity 42.5%;
Matches 34; Conservative 0; Mismatches 0; Indels 46; Gaps 2;
Qy 1 NYWIN--------------NIYPSYIYTNYNQEFKD------------------------ 22
||||| |||||||||||||||||
Db 31 NYWINWVKQRPGQGLEWIGNIYPSYIYTNYNQEFKDKVTLTVDESSSTAYMQLSSPTSED 90
Qy 23 --------SPYGYDEYGLDY 34
||||||||||||
Db 91 SAVYYCTRSPYGYDEYGLDY 110
RESULT 16 from 4fus5fus6.align.rapbm database.
US-11-202-507A-11
(NOTE: this sequence has 1 duplicate in the database searched.
See complete list at the end of this report)
Sequence 11, US/11202507A
Publication No. US20060057111A1
GENERAL INFORMATION
APPLICANT: Hedlund, Gunnar
APPLICANT: Forsberg, Goran
APPLICANT: Wallen-Ohman, Marie
TITLE OF INVENTION: TREATMENT OF HYPERPROLIFERATIVE DISEASE WITH SUPERANTIGENS IN
TITLE OF INVENTION: COMBINATION WITH ANOTHER ANTICANCER AGENT
FILE REFERENCE: P03024US1
CURRENT APPLICATION NUMBER: US/11/202,507A
CURRENT FILING DATE: 2005-08-12
PRIOR APPLICATION NUMBER: US 60/601,548
PRIOR FILING DATE: 2004-08-13
NUMBER OF SEQ ID NOS: 16
SEQ ID NO 11
LENGTH: 678
TYPE: PRT
ORGANISM: Staphylococcus sp
Query Match 85.6%; Score 147.3; Length 678;
Best Local Similarity 41.2%;
Matches 33; Conservative 0; Mismatches 0; Indels 47; Gaps 2;
Qy 1 KSSQSLLNSRNQKNYLT---------------WASTRES--------------------- 24
||||||||||||||||| |||||||
Db 483 KSSQSLLNSRNQKNYLTWYQQKPGQPPKLLIYWASTRESGVPDRFTGSGSGTDFTLTISS 542
Qy 25 -----------QNDYVYPLT 33
|||||||||
Db 543 VQAEDLAVYYCQNDYVYPLT 562
RESULT 20 from 8.align.rapbm database.
US-11-202-507A-11
(NOTE: this sequence has 1 duplicate in the database searched.
See complete list at the end of this report)
Sequence 11, US/11202507A
Publication No. US20060057111A1
GENERAL INFORMATION
APPLICANT: Hedlund, Gunnar
APPLICANT: Forsberg, Goran
APPLICANT: Wallen-Ohman, Marie
TITLE OF INVENTION: TREATMENT OF HYPERPROLIFERATIVE DISEASE WITH SUPERANTIGENS IN
TITLE OF INVENTION: COMBINATION WITH ANOTHER ANTICANCER AGENT
FILE REFERENCE: P03024US1
CURRENT APPLICATION NUMBER: US/11/202,507A
CURRENT FILING DATE: 2005-08-12
PRIOR APPLICATION NUMBER: US 60/601,548
PRIOR FILING DATE: 2004-08-13
NUMBER OF SEQ ID NOS: 16
SEQ ID NO 11
LENGTH: 678
TYPE: PRT
ORGANISM: Staphylococcus sp
Query Match 90.4%; Score 590; Length 678;
Best Local Similarity 88.4%;
Matches 107; Conservative 8; Mismatches 6; Indels 0; Gaps 0;
Qy 1 QVQLVQSGAEVKKPGASVKVSCKASGYTFTNYWINWVRQAPGQGLEWIGNIYPSYIYTNY 60
|||| | |||: :||||||:|||||||||||||||||:| ||||||||||||||||||||
Db 1 QVQLQQPGAELVRPGASVKLSCKASGYTFTNYWINWVKQRPGQGLEWIGNIYPSYIYTNY 60
Qy 61 NQEFKDKVTLTVDESTSTAYMELSSLRSEDTAVYYCTRSPYGYDEYGLDYWGQGTTVTVS 120
|||||||||||||||:|||||:||| |||:||||||||||||||||||||||||:||||
Db 61 NQEFKDKVTLTVDESSSTAYMQLSSPTSEDSAVYYCTRSPYGYDEYGLDYWGQGTSVTVS 120
Qy 121 S 121
|
Db 121 S 121
RESULT 21
US-11-202-507A-5
(NOTE: this sequence has 13 duplicates in the database searched.
See complete list at the end of this report)
Sequence 5, US/11202507A
Publication No. US20060057111A1
GENERAL INFORMATION
APPLICANT: Hedlund, Gunnar
APPLICANT: Forsberg, Goran
APPLICANT: Wallen-Ohman, Marie
TITLE OF INVENTION: TREATMENT OF HYPERPROLIFERATIVE DISEASE WITH SUPERANTIGENS IN
TITLE OF INVENTION: COMBINATION WITH ANOTHER ANTICANCER AGENT
FILE REFERENCE: P03024US1
CURRENT APPLICATION NUMBER: US/11/202,507A
CURRENT FILING DATE: 2005-08-12
PRIOR APPLICATION NUMBER: US 60/601,548
PRIOR FILING DATE: 2004-08-13
NUMBER OF SEQ ID NOS: 16
SEQ ID NO 5
LENGTH: 679
TYPE: PRT
ORGANISM: Artificial Sequence
FEATURE:
OTHER INFORMATION: Conjugated Protein
FEATURE:
NAME/KEY: MISC_FEATURE
LOCATION: (460)..(679)
OTHER INFORMATION: Light Chain
Query Match 90.4%; Score 590; Length 679;
Best Local Similarity 88.4%;
Matches 107; Conservative 8; Mismatches 6; Indels 0; Gaps 0;
Qy 1 QVQLVQSGAEVKKPGASVKVSCKASGYTFTNYWINWVRQAPGQGLEWIGNIYPSYIYTNY 60
|||| | |||: :||||||:|||||||||||||||||:| ||||||||||||||||||||
Db 1 QVQLQQPGAELVRPGASVKLSCKASGYTFTNYWINWVKQRPGQGLEWIGNIYPSYIYTNY 60
Qy 61 NQEFKDKVTLTVDESTSTAYMELSSLRSEDTAVYYCTRSPYGYDEYGLDYWGQGTTVTVS 120
|||||||||||||||:|||||:||| |||:||||||||||||||||||||||||:||||
Db 61 NQEFKDKVTLTVDESSSTAYMQLSSPTSEDSAVYYCTRSPYGYDEYGLDYWGQGTSVTVS 120
Qy 121 S 121
|
Db 121 S 121
Conclusion
8. Any inquiry concerning this communication or earlier communications from the Examiner should be directed to ALANA HARRIS DENT whose telephone number is (571)272-0831. The Examiner works a flexible schedule, however can generally be reached between 8AM-8PM, Monday through Friday.
Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice.
If attempts to reach the Examiner by telephone are unsuccessful, the Examiner’s supervisor, Julie Wu can be reached at 571-272-5205. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300.
Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000.
ALANA HARRIS DENT
Primary Examiner
Art Unit 1643
21 April 2026
/Alana Harris Dent/Primary Examiner, Art Unit 1643
Prosecution Insights