Prosecution Insights
Last updated: April 19, 2026
Application No. 18/115,402

Wearable Engineered Human Skin and Systems and Methods for Making the Same

Non-Final OA §102
Filed
Feb 28, 2023
Examiner
TICHY, JENNIFER M.H.
Art Unit
1653
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
The Trustees of Columbia University in the City of New York
OA Round
1 (Non-Final)
65%
Grant Probability
Favorable
1-2
OA Rounds
3y 2m
To Grant
99%
With Interview

Examiner Intelligence

Grants 65% — above average
65%
Career Allow Rate
395 granted / 606 resolved
+5.2% vs TC avg
Strong +34% interview lift
Without
With
+34.4%
Interview Lift
resolved cases with interview
Typical timeline
3y 2m
Avg Prosecution
77 currently pending
Career history
683
Total Applications
across all art units

Statute-Specific Performance

§101
3.7%
-36.3% vs TC avg
§103
36.0%
-4.0% vs TC avg
§102
20.2%
-19.8% vs TC avg
§112
29.1%
-10.9% vs TC avg
Black line = Tech Center average estimate • Based on career data from 606 resolved cases

Office Action

§102
DETAILED ACTION The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Applicant's election without traverse of Group I, claims 1-6 in the reply filed on 25 November 2025 is acknowledged. Claims 7-20 have been withdrawn. Claims 2-6 have been amended. Claims 1-6 are currently pending and under examination. This Application is a continuation of International Application PCT/US2021/049671, filed September 9, 2021, which claims benefit of priority to U.S. Provisional Application No. 63/077029, filed September 11, 2020. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claims 1 and 2 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Wikipedia (File:Feet in socks.jpg, 27 August 2006, Available online at: en.wikipedia.org/wiki/File: Feet_in_socks.jpg). PNG media_image1.png 432 370 media_image1.png Greyscale With regard to claim 1, referring to the reproduced picture, Wikipedia teaches a sock, which is a skin substitute comprising an outer-facing portion (outside of the sock) and an inner-facing portion (inside of the sock), the skin substitute configured to conform to the shape and dimension of the desired body part of the subject, here, the foot, ankle, and lower calf, wherein the skin substitute circles back on itself to enclose the foot, ankle, and lower calf (see picture). With regard to claim 2, referring to the reproduced picture, Wikipedia teaches a skin substitute having an outer-facing portion, which is an epidermal portion, and an inner-facing portion, which is a dermal portion. Claims 1-6 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Atala et al. (IDS; US 2017/0354763, Published 2017). With regard to claim 1, Atala et al. teach a skin substitute, including a biomask, comprising an outer-facing portion (outer side) and an inner-facing portion (inner side), the skin substitute configured to conform to the shape and dimension of the desired body part of the subject, here, a portion of the face including the nose, lips, chin, and cheeks (Abs.; Fig. 6). The skin substitute biomask circles back on itself to enclose the nose, lips, chin, and cheeks (see Fig. 6). With regard to claim 2, Atala et al. teach that the skin substitute has an epidermis-like layer, which is an outer-facing portion and epidermal portion; and a dermis-like layer, which is an inner portion and dermal portion (Abs.). With regard to claims 3-6, Atala et al. teach that the epidermal portion includes epidermal cells, including keratinocytes and melanocytes; and the dermal portion includes dermal cells, including fibroblasts and dermal papilla cells (Abs.). Conclusion No claims are allowable. Any inquiry concerning this communication or earlier communications from the examiner should be directed to JENNIFER M.H. TICHY whose telephone number is (571)272-3274. The examiner can normally be reached Monday-Thursday, 9:00am-7:00pm ET. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Sharmila G. Landau can be reached at (571)272-0614. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /JENNIFER M.H. TICHY/Primary Examiner, Art Unit 1653
Read full office action

Prosecution Timeline

Feb 28, 2023
Application Filed
Dec 10, 2025
Non-Final Rejection — §102 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
65%
Grant Probability
99%
With Interview (+34.4%)
3y 2m
Median Time to Grant
Low
PTA Risk
Based on 606 resolved cases by this examiner. Grant probability derived from career allow rate.

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