Prosecution Insights
Last updated: July 17, 2026
Application No. 18/119,446

MODIFIED COMPOUND AND MANUFACTURE METHOD THEREOF

Final Rejection §102
Filed
Mar 09, 2023
Priority
Mar 10, 2022 — provisional 63/269,111
Examiner
DAVIDSON IV, CULLEN LEE GARRETT
Art Unit
1767
Tech Center
1700 — Chemical & Materials Engineering
Assignee
National Yang Ming Chiao Tung University
OA Round
2 (Final)
39%
Grant Probability
At Risk
3-4
OA Rounds
3m
Est. Remaining
84%
With Interview

Examiner Intelligence

Grants only 39% of cases
39%
Career Allowance Rate
27 granted / 70 resolved
-26.4% vs TC avg
Strong +45% interview lift
Without
With
+45.3%
Interview Lift
resolved cases with interview
Typical timeline
3y 7m
Avg Prosecution
36 currently pending
Career history
120
Total Applications
across all art units

Statute-Specific Performance

§103
76.2%
+36.2% vs TC avg
§102
8.3%
-31.7% vs TC avg
§112
0.3%
-39.7% vs TC avg
Black line = Tech Center average estimate • Based on career data from 70 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Priority Applicant note within the arguments filed March 16, 2026 that the Priority Document was retrieved by the Office on March 10, 2022 and has not yet acknowledged the receipt in any of the previously mailed Office Actions. However, the priority document is not present in the record as of the mailing of this Office Action. It is noted that the Application Data Sheet filed March 9, 2023 does not indicate that Applicant claims foreign priority. Response to Amendments and Arguments Applicant’s amendments and arguments, filed March 16, 2026, with respect to the rejection(s) under 35 U.S.C. 102(a)(1) in view of Sato et al. (cited in the previous Office Action) have been fully considered but they are not persuasive. Applicant has amened claim 1 to recite the structure limitations from newly canceled claim 3 and to additionally recite a group of amino acid moieties. While the rejection within the previous Office Action relied upon the teaching of Example I-6 of Sato having a methionine group (not recited within the newly amended group), various other examples of Sato teach exemplary structures which read on the claimed formula 1 and are fully addressed within the new rejection below. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim 1 is rejected under 35 U.S.C. 102(a)(1) as being anticipated by Sato et al. (JP-2001226345-A, English translation provided for citations, hereinafter referred to as "Sato"). As to Claim 1: Sato teaches compounds including esters of N-(meth)acryloyl-amino acids containing ether bonds ([0001]) which may have the structure represented by formula (I) (see foreign document pg. 2): PNG media_image1.png 141 260 media_image1.png Greyscale wherein R1 is H or a methyl group (i.e., an acryl group or alkylacryl group), X is a residue of an amino acid (i.e., an amino acid moiety), and R2 may be (CH2CH2O)n wherein n is an integer of 1 to 5 ([0009]) (i.e., a polyether segment having an end comprising oxygen). Sato further teaches an exemplary structure having the formula (see pg. 5 of foreign reference): PNG media_image2.png 177 174 media_image2.png Greyscale wherein r1 = H, r2 = CH2OH (i.e., serine, an amino acid), and r3 = (CH2CH2O)3CH3 (entry I-83 of table on pg. 7 of foreign reference), which anticipates the claimed compound. Sato teaches various other exemplary compounds having the same r1 and r3 values as the above, differing in the identity of the amino acid moiety which further reads on the breadth of the claimed group of amino acid side chains (e.g., at least examples I-132 (lysine), I-114 (tyrosine), I-151 (aspartic acid)). Conclusion Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Correspondence Any inquiry concerning this communication or earlier communications from the examiner should be directed to CULLEN L. G. DAVIDSON IV whose telephone number is (703)756-1073. The examiner can normally be reached M-F 9:30-6:00. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Mark Eashoo can be reached on (571) 272-1197. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /C.L.G.D./ Examiner, Art Unit 1767 /MARK EASHOO/Supervisory Patent Examiner, Art Unit 1767
Read full office action

Prosecution Timeline

Mar 09, 2023
Application Filed
Dec 22, 2025
Non-Final Rejection mailed — §102
Mar 16, 2026
Response Filed
May 21, 2026
Final Rejection mailed — §102 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
39%
Grant Probability
84%
With Interview (+45.3%)
3y 7m (~3m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 70 resolved cases by this examiner. Grant probability derived from career allowance rate.

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