Prosecution Insights
Last updated: April 19, 2026
Application No. 18/146,472

HIGH-EFFICIENCY CYCLIC PREPARATION METHOD FOR COLUMNAR TAURINE

Non-Final OA §112
Filed
Dec 27, 2022
Examiner
DOLETSKI, BLAINE G
Art Unit
1692
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Qianjiang Yongan Pharmaceutical Co. Ltd.
OA Round
1 (Non-Final)
76%
Grant Probability
Favorable
1-2
OA Rounds
2y 2m
To Grant
83%
With Interview

Examiner Intelligence

Grants 76% — above average
76%
Career Allow Rate
415 granted / 548 resolved
+15.7% vs TC avg
Moderate +7% lift
Without
With
+7.2%
Interview Lift
resolved cases with interview
Typical timeline
2y 2m
Avg Prosecution
26 currently pending
Career history
574
Total Applications
across all art units

Statute-Specific Performance

§101
0.5%
-39.5% vs TC avg
§103
41.1%
+1.1% vs TC avg
§102
15.7%
-24.3% vs TC avg
§112
26.3%
-13.7% vs TC avg
Black line = Tech Center average estimate • Based on career data from 548 resolved cases

Office Action

§112
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . DETAILED ACTION Claim Status Claims 1-21 are pending. Claims 1-21 are under examination. Claims 1-21 are rejected. No claims allowed. Interview 03/02/2026 Applicant declined the suggestion by the examiner to delete the preferable phrases in the claims to place the application in condition for allowance. NOTE: The below 112(b) rejection of claim 1 and dependent claims due to the relative term “A high-efficiency cyclic preparation” was not discussed in the interview. Filing Receipt PNG media_image1.png 94 990 media_image1.png Greyscale PNG media_image2.png 44 988 media_image2.png Greyscale PNG media_image3.png 108 989 media_image3.png Greyscale PNG media_image4.png 73 976 media_image4.png Greyscale Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claims 1-21 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Claim 1 recites “A high-efficiency cyclic preparation method”. This phrase is a relative term. The term “A high-efficiency cyclic preparation method” in claim 1 is a relative term which renders the claim indefinite. The term “A high-efficiency cyclic preparation method” is not defined by the claim, the specification does not provide a standard for ascertaining the requisite degree, and one of ordinary skill in the art would not be reasonably apprised of the scope of the invention. In the instant case one cannot ascertain the degree of ‘high-efficiency”. This high-efficiency could mean 99% or 85% or 80% efficiency. These values contradict each other. The dependent claims are also indefinite because the dependent claims do not clarify the indefinite phrase of claim 1. Claims 8-9, 11-13, 15-17 and 19-20 have preferable phrases. It is not clear whether the preferable phrases are limitations. MPEP 2173.05(D): Description of examples or preferences is properly set forth in the specification rather than the claims. If stated in the claims, examples and preferences may lead to confusion over the intended scope of a claim. Deletion of the preferable phrases in their entirety will obviate this rejection. Allowable Subject Matter Claims 1-21 would be allowable upon obviating the current 112(b) rejection. The closest prior art to the invention is Chen et al. (EP3786153, Published 03/03/2021). The closest prior art does not pertain to the current invention as discussed below. Chen et al. teach the following on page 4. PNG media_image5.png 54 1069 media_image5.png Greyscale PNG media_image6.png 86 1064 media_image6.png Greyscale PNG media_image7.png 44 1062 media_image7.png Greyscale PNG media_image8.png 77 1064 media_image8.png Greyscale The above teachings differ from the claimed invention in that the collected effluent containing taurine post resin treatment is sent to an ammonia gas process. Whereas the claimed invention crystalizes the taurine effluent. It would not have been obvious to have modified the prior art to arrive at the current invention. There being no motivation to do so. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to BLAINE G DOLETSKI whose telephone number is (571)272-2766. The examiner can normally be reached M-F 7-4 EST. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Scarlett Goon can be reached at (571)270-5241. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /B.G.D/Examiner, Art Unit 1692 /Andrew D Kosar/ Supervisory Patent Examiner, Art Unit 1625
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Prosecution Timeline

Dec 27, 2022
Application Filed
Mar 02, 2026
Examiner Interview (Telephonic)
Mar 11, 2026
Non-Final Rejection — §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
76%
Grant Probability
83%
With Interview (+7.2%)
2y 2m
Median Time to Grant
Low
PTA Risk
Based on 548 resolved cases by this examiner. Grant probability derived from career allow rate.

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