Office Action Predictor
Last updated: April 15, 2026
Application No. 18/184,298

TRANSVERSE SHEET ILLUMINATION MICROSCOPY(TRANSIM)

Non-Final OA §102
Filed
Mar 15, 2023
Examiner
LAVARIAS, ARNEL C
Art Unit
2872
Tech Center
2800 — Semiconductors & Electrical Systems
Assignee
The Regents Of The University Of California
OA Round
1 (Non-Final)
79%
Grant Probability
Favorable
1-2
OA Rounds
2y 10m
To Grant
79%
With Interview

Examiner Intelligence

Grants 79% — above average
79%
Career Allow Rate
655 granted / 825 resolved
+11.4% vs TC avg
Minimal -1% lift
Without
With
+-0.8%
Interview Lift
resolved cases with interview
Typical timeline
2y 10m
Avg Prosecution
22 currently pending
Career history
847
Total Applications
across all art units

Statute-Specific Performance

§101
1.1%
-38.9% vs TC avg
§103
34.8%
-5.2% vs TC avg
§102
33.0%
-7.0% vs TC avg
§112
18.7%
-21.3% vs TC avg
Black line = Tech Center average estimate • Based on career data from 825 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Election/Restrictions Applicant’s election without traverse of Invention I (Claims 2, 7-8) in the reply filed on 11/24/2025 is acknowledged. Claims 3-6, 9-16 are withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to nonelected inventions, there being no allowable generic or linking claim. Election was made without traverse in the reply filed on 11/24/2025. Priority Acknowledgment is made of applicant’s claim for priority under 35 U.S.C. 119 (e) and 120. Drawings The originally filed drawings were received on 3/15/2023. These drawings are acceptable. Specification The lengthy specification has not been checked to the extent necessary to determine the presence of all possible minor errors. Applicant’s cooperation is requested in correcting any errors of which applicant may become aware in the specification. Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 7-8 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Fiolka (U.S. Patent Application Publication US 2019/0170646 A1). Fiolka discloses an axially illuminated microscope (See for example Abstract; Figures 1-17; in particular Figures 1-3, 11-13, and Figures 7-8 (prior art embodiment)) for multiple plane imaging configured to achieve simultaneous imaging of multiple z-planes in laser scanning confocal fluorescence microscopy (See for example Paragraphs 0049-0057; Paragraphs 0004-0006 (prior art embodiment)). Fiolka additionally discloses an improved laser scanning confocal fluorescence microscope (See for example Abstract; Figures 1-17; in particular Figures 1-3, 11-13, and Figures 7-8 (prior art embodiment)), the improvement comprising configuring said microscope with axial illumination for multiple plane imaging that achieves simultaneous imaging of multiple z-planes (See for example Paragraphs 0049-0057; Paragraphs 0004-0006 (prior art embodiment)). Allowable Subject Matter Claims 1-2 are allowed. The following is a statement of reasons for the indication of allowable subject matter: Claim 1 is allowable over the cited art of record for at least the reason that the cited art of record fails to teach or reasonably suggest a transverse sheet illumination microscopy apparatus as generally set forth in Claim 1, the apparatus including, in combination with the features recited in Claim 1, the imaging unit comprising a linear reflection cavity with an imaging sensor; wherein the imaging unit is configured to select one plane at a time from a plurality of image planes from the sample and remap the selected plane to the imaging sensor; wherein each round trip in the linear reflection cavity allows for an additional plane to be segmented and re-adjusted onto the imaging sensor for imaging the sample. Claim 2 is dependent on Claim 1, and hence is allowable for at least the same reasons Claim 1 is allowable. Conclusion The prior art made of record and not relied upon is considered pertinent to applicant's disclosure. U.S. Patent No. 9810896 to Nishiwaki. U.S. Patent No. 10746981 to Tomer et al. U.S. Patent Application Publication US 2014/0139840 A1 to Judkewitz et al. Any inquiry concerning this communication or earlier communications from the examiner should be directed to ARNEL C LAVARIAS whose telephone number is (571)272-2315. The examiner can normally be reached M-F 10:30 AM-7 PM. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Stephone Allen can be reached at 571-272-2434. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. ARNEL C. LAVARIAS Primary Examiner Group Art Unit 2872 12/12/2025 /ARNEL C LAVARIAS/Primary Examiner, Art Unit 2872
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Prosecution Timeline

Mar 15, 2023
Application Filed
Dec 15, 2025
Non-Final Rejection — §102
Apr 06, 2026
Response Filed

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
79%
Grant Probability
79%
With Interview (-0.8%)
2y 10m
Median Time to Grant
Low
PTA Risk
Based on 825 resolved cases by this examiner. Grant probability derived from career allow rate.

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