Prosecution Insights
Last updated: April 19, 2026
Application No. 18/196,343

Silica-based nanoparticles for PFAS remediation

Final Rejection §102§112
Filed
May 11, 2023
Examiner
ROYCE, LIAM A
Art Unit
1777
Tech Center
1700 — Chemical & Materials Engineering
Assignee
The Connecticut Agricultural Experiment Station
OA Round
2 (Final)
65%
Grant Probability
Moderate
3-4
OA Rounds
2y 10m
To Grant
87%
With Interview

Examiner Intelligence

Grants 65% of resolved cases
65%
Career Allow Rate
339 granted / 522 resolved
At TC average
Strong +22% interview lift
Without
With
+21.7%
Interview Lift
resolved cases with interview
Typical timeline
2y 10m
Avg Prosecution
39 currently pending
Career history
561
Total Applications
across all art units

Statute-Specific Performance

§101
0.6%
-39.4% vs TC avg
§103
44.3%
+4.3% vs TC avg
§102
17.8%
-22.2% vs TC avg
§112
33.2%
-6.8% vs TC avg
Black line = Tech Center average estimate • Based on career data from 522 resolved cases

Office Action

§102 §112
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Response to Arguments The Amendment filed 08DEC2025 has been entered. No new matter has been entered. Applicant’s amendments have overcome each and every claim objections previously set forth in the Non-Final Office Action mailed 09SEPT2025. Applicant's arguments filed 08DEC2025 have been fully considered but they are not persuasive. With respect to claim 3, please clarify the desired claim scope. Regarding the 102, the Examiner disagrees. The independent claim 1 sets forth an ultraporous mesostructured nanoparticle suitable for uptake by a plant. A recitation of the intended use of the claimed invention must result in a structural difference between the claimed invention and the prior art in order to patentably distinguish the claimed invention from the prior art. If the prior art structure is capable of performing the intended use, then it meets the claim. WANG’s nanoparticle is capable of the intended use. Just because WANG’s nanoparticle is suitable for a different application or is capable of regeneration at high temperatures does not mean it is not capable of Applicant’s intended purpose. See e.g. WYSZKOWSKI 2023 “Molecular sieve, halloysite, sepiolite and expanded clay as a tool in reducing the content of trace elements in Helianthus annuus L. on copper-contaminated soil”. Furthermore, the independent claim 1 sets forth an ultraporous mesostructured nanoparticle being modified with e.g. APTES. WANG’s silica nanoparticle is modified with e.g. APTES: “the 3-amino-propyl triethoxy silane (APTES) was introduced to react with the silicon hydroxyl groups in the MCM-48 channels” (P2/right C/2.1. Preparation of Au/MCM-48 absorbent). Similarly, WANG’s silica nanoparticle is modified with e.g. TMCS: “the 3-amino-propyl triethoxy silane (APTES) was introduced to react with the silicon hydroxyl groups in the MCM-48 channels” (P2/right C/2.1. Preparation of Au/MCM-48 absorbent). If there are doubts about the materials and methods, see the supplemental data of WANG. The Applicant has not adequately described in the claims a difference in structure. The claims do not claim a surface-modified ultraporous mesostructured nanoparticle nor require silylation or a surface-grafting step. In response to applicant's argument that the references fail to show certain features of the invention (e.g. surface modification or silica only or dual-scale pore structure, very large internal mesopores, and substantial pore volumes, hierarchical pore structure), it is noted that the features upon which applicant relies are not recited in the rejected claim(s). Although the claims are interpreted in light of the specification, limitations from the specification are not read into the claims. See In re Van Geuns, 988 F.2d 1181, 26 USPQ2d 1057 (Fed. Cir. 1993). Respectfully, the claims are directed towards an ultraporous mesostructured nanoparticle, not a method of synthesis. WANG’s mesostructure is ultraporous, which is why these materials are used as catalysts and molecular sieves. Product-by-Process Claims Note that product-by-process claims are not limited to the manipulations of the recited steps, only the structure implied by the steps. (See MPEP §2113). Claims 1-3,5 are interpreted as product-by-process claims and will be examined upon the merits of such claims. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. Claim 3 is rejected under 35 U.S.C. 112(b) as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor regards as the invention. Claim 3 sets forth the limitation “the ultraporous mesostructured silica nanoparticle is further modified with chlorotrimethylsilane”. Claim 3 is dependent on claim 1, which already claims “an ultraporous mesostructured nanoparticle […] modified with […] chlorotrimethylsilane”. The scope is unclear as to whether the nanoparticle is only modified with chlorotrimethylsilane or is a combination of chlorotrimethylsilane and another species of the modification genus. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 1-3,5 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by WANG et. al. “Ultrafine Au nanoparticles confined in three-dimensional mesopores of MCM-48 for efficient and regenerable Hg0 removal sorbent in H2S and H2O containing natural gas”. Regarding claims 1-3,5, WANG teaches an ultraporous mesostructured nanoparticle (”ultraporous” by being a fine mesoporous nanoparticle with a large surface area; title, P2/left C/last paragraph leading into P2/right C) being modified with (3-aminopropyl)triethoxysilane (APTES) and chlorotrimethylsilane (TMS or trimethylchlorosilane (TMCS); P2/left C/last paragraph leading into P2/right C). Note that MCM-48 is a mesoporous silica (zeolite; P2/right C/2.1. Preparation of Au/MCM-48 absorbent). Telephonic Inquiries THIS ACTION IS MADE FINAL. Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to LIAM A ROYCE whose telephone number is (571)270-0352. The examiner can normally be reached M-F ~08:00~15:00. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Benjamin Lebron can be reached at (571)272-0475. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. LIAM A. ROYCE Primary Examiner Art Unit 1777 /Liam Royce/ Primary Examiner, Art Unit 1777
Read full office action

Prosecution Timeline

May 11, 2023
Application Filed
Sep 05, 2025
Non-Final Rejection — §102, §112
Dec 08, 2025
Response Filed
Mar 03, 2026
Final Rejection — §102, §112 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12595191
Wastewater Unit With Internal Sandwiched Connector
2y 5m to grant Granted Apr 07, 2026
Patent 12576347
HOT ROLLING MILL WITH SEPARATOR FOR MILL SCALE FROM WASTEWATER
2y 5m to grant Granted Mar 17, 2026
Patent 12569782
COMPOSITIONS AND RELATED KITS AND METHODS FOR WATER TREATMENT
2y 5m to grant Granted Mar 10, 2026
Patent 12564833
KIT FOR ISOLATION OF PLATELET-RICH PLASMA AND THE METHOD USING THE SAME
2y 5m to grant Granted Mar 03, 2026
Patent 12559392
Sustainable System and Method for Removing and Concentrating Per- and Polyfluoroalkyl Substances (PFAS) from Water
2y 5m to grant Granted Feb 24, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

AI Strategy Recommendation

Get an AI-powered prosecution strategy using examiner precedents, rejection analysis, and claim mapping.
Powered by AI — typically takes 5-10 seconds

Prosecution Projections

3-4
Expected OA Rounds
65%
Grant Probability
87%
With Interview (+21.7%)
2y 10m
Median Time to Grant
Moderate
PTA Risk
Based on 522 resolved cases by this examiner. Grant probability derived from career allow rate.

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month