Office Action Predictor
Last updated: April 15, 2026
Application No. 18/196,968

ENTERO-ANTISEPTIC FOR THE TREATMENT OF GASTROINTESTINAL INFECTIONS IN HUMANS

Non-Final OA §101§102§112
Filed
May 12, 2023
Examiner
GONZALEZ, LUISALBERTO
Art Unit
1624
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Unknown
OA Round
1 (Non-Final)
62%
Grant Probability
Moderate
1-2
OA Rounds
2y 9m
To Grant
99%
With Interview

Examiner Intelligence

Grants 62% of resolved cases
62%
Career Allow Rate
84 granted / 135 resolved
+2.2% vs TC avg
Strong +48% interview lift
Without
With
+48.2%
Interview Lift
resolved cases with interview
Typical timeline
2y 9m
Avg Prosecution
55 currently pending
Career history
190
Total Applications
across all art units

Statute-Specific Performance

§101
2.8%
-37.2% vs TC avg
§103
36.8%
-3.2% vs TC avg
§102
12.5%
-27.5% vs TC avg
§112
29.6%
-10.4% vs TC avg
Black line = Tech Center average estimate • Based on career data from 135 resolved cases

Office Action

§101 §102 §112
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Detailed Action Filing Receipt and Priority The filing receipt mailed 08/16/2023 states that the instant application does not claim benefit of any prior filed domestic applications. Information Disclosure Statement As of this action, no information disclosure statement (IDS) has been submitted. Claim Objections Claim 3 is objected to under 37 CFR 1.75(c) as being in improper form because a multiple dependent claim. Claim 3 states “Use of the compound according to the patent claim 1 and claim 2”. See MPEP § 608.01(n). For the purpose of this action, the claim is being treated as if dependent from claim 2. Rejections Claim Rejections - 35 USC § 101 Use Claim 35 U.S.C. 101 reads as follows: Whoever invents or discovers any new and useful process, machine, manufacture, or composition of matter, or any new and useful improvement thereof, may obtain a patent therefor, subject to the conditions and requirements of this title. Claims 2-3 are rejected under 35 U.S.C. 101 because the claimed invention is directed to non-statutory subject matter. The claim(s) does/do not fall within at least one of the four categories of patent eligible subject matter. Claim 2 states “Use of the compound, according to the patent claim 1,…” Claim 3 states “Use of the compound according to the patent claim 1 and claim 2…”. Claim Rejections - 35 USC § 112(b) Use Claim The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claims 2-3 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Regarding the rejections above, the MPEP in section 2173.05(q), subsection I states “It is appropriate to reject a claim that recites a use but fails to recite steps under 35 U.S.C. 101 and 35 U.S.C. 112(b) if the facts support both rejections.” A “use” is not a statutory class. Therefore rejection under 35 U.S.C. 101 is proper. Additionally, claims 2 and 3 do not recite a functional step. Therefore, rejection under 35 U.S.C. is also proper. For the purpose of this action, the claims are being interpreted as if the claims are drawn method of treating claims. Indefiniteness Claim 1 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Claim 1 states “A compound manufactured with the procedure of synthesis of bouncing Thymol and Carvacrol into one solid and stabile compound…”. Within the chemical arts, “bouncing” is not a known synthetic technique. The instant specification is silent to the specific steps or methods involved in “bouncing”. Therefore, the claim is indefinite because of its use of “bouncing” which is not defined or explained. One of ordinary skill in the art would not know the metes of bounds of the claims from what is provided in the claim and in the specification. Claim 1 is rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Claim 1 states “A compound…”as shown in paragraph 0009”. The MPEP section 2173.05(s) states “Where possible, claims are to be complete in themselves. Incorporation by reference to a specific figure or table ‘is permitted only in exceptional circumstances where there is no practical way to define the invention in words and where it is more concise to incorporate by reference than duplicating a drawing or table into the claims. Incorporation by reference is a necessity doctrine, not or applicant’s convenience.’ [citations omitted]”. Additionally, the specification may be modified or changed. Therefore, reference to a specific paragraph within the specification is indefinite. Claims 2-3 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Claims 2-3 contain “/”. This is indefinite because one of ordinary skill would not know from the claim language whether the claim is drawn to one or the other or both. It is not clear whether the claim is meant to state “active compound or potent entero-antiseptic” or “active compound and potent entero-antiseptic”. The examiner recommends amending to state “and”, ”or” or “and/or”. Art Rejections Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. (a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention. Claim(s) 1-3 is/are rejected under 35 U.S.C. 102(a)(1) and (a)(2) as being anticipated by Ninkov (EP 3991725 A1, published 04/05/2022, date of filing 02/11/2020). Ninkov on p. 4 discloses a compound of Formula I shown below. Formula I Ninkov on p. 2, para. [0002] states “In particular, this invention is completely novel because Thymol and Carvacrol, by the special process of synthesis have been bounced into one stabile compound.” Ninkov in the same paragraph states “The compound is created to fight antibiotic resistance of pathogenic bacteria, such as E. coli, Salmonella, Campylobacter, Shigella, Vibrio, Yersinia, Listeria and other bacteria…”. Ninkov in its abstract (p. 1) states “Additionally, [the compound’s] second formulation, with the coated cellulose, is used as an active compound/potent entero-antiseptic for the treatment of chronic intestinal infections: Chron’s Disease (inflammatory bowel disease – IBD).” Pertinent Art Kachur (Critical reviews in Food Science and Nutrition, 2020, vol. 60, No. 18, 3042-3053) discusses the antibacterial properties of thymol and carvacrol. Mahboubi (Journal of Dietary Supplements, Vol. 16, 2019, Iss. 1, only abstract provided) discusses the use of Z. multiflora essential oils, which includes thymol and carvacrol, in treatment for IBD. Conclusion No claims allowed. Any inquiry concerning this communication or earlier communications from the examiner should be directed to LUISALBERTO GONZALEZ whose telephone number is (571)272-1154. The examiner can normally be reached M-F 8:30-5:30. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Jeffrey Murray can be reached at (571) 272-9023. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /L.G./Examiner, Art Unit 1624 /SUSANNA MOORE/Primary Examiner, Art Unit 1624
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Prosecution Timeline

May 12, 2023
Application Filed
Sep 02, 2025
Non-Final Rejection — §101, §102, §112
Apr 08, 2026
Response after Non-Final Action

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
62%
Grant Probability
99%
With Interview (+48.2%)
2y 9m
Median Time to Grant
Low
PTA Risk
Based on 135 resolved cases by this examiner. Grant probability derived from career allow rate.

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