Prosecution Insights
Last updated: April 19, 2026
Application No. 18/227,719

BIOSYNTHESIS OF SUBSTITUTED COMPOUNDS AND CANNABINOIDS

Non-Final OA §112
Filed
Jul 28, 2023
Examiner
HENLEY III, RAYMOND J
Art Unit
1629
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Invizyne Technologies Inc.
OA Round
1 (Non-Final)
83%
Grant Probability
Favorable
1-2
OA Rounds
2y 0m
To Grant
86%
With Interview

Examiner Intelligence

Grants 83% — above average
83%
Career Allow Rate
1041 granted / 1248 resolved
+23.4% vs TC avg
Minimal +2% lift
Without
With
+2.1%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 0m
Avg Prosecution
31 currently pending
Career history
1279
Total Applications
across all art units

Statute-Specific Performance

§101
4.0%
-36.0% vs TC avg
§103
19.4%
-20.6% vs TC avg
§102
10.0%
-30.0% vs TC avg
§112
30.1%
-9.9% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1248 resolved cases

Office Action

§112
CLAIMS 1-20 ARE PRESENTED FOR EXAMINATION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Applicant’s Information Disclosure Statements filed July 28, 2023, November 15, 2023 and January 28, 2026 have been received and entered into the application. As reflected by the attached, completed copies of form PTO/SB/08, the cited references have been considered. As per the Restriction Requirement issued November 17, 2025, Applicants have elected, without traverse, the invention of Group I, claims 1-10, directed to a cannabinoid composition comprising a cannabinoid derived from a deuterated fatty acid and a cannabinoid compound. Applicant has further elected specific species for examination purposes. The Examiner has expanded the search of claims 1-10 to the broadest reasonable interpretation of the claimed subject matter, not having found the specific, elected subject matter. The requirement for restriction is deemed to remain proper and is hereby made FINAL. Claims 11-20 are withdrawn from consideration as being directed to subject matter not elected without traverse under 37 CFR 1.142(b). Claims 1-10 are herein acted on the merits. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claims 1-10 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. In claim 1, the poor print quality of the structure depicted therein gives rise to ambiguities as to bond interpretation and substituent identification. In claim 4, since this claim fails to indicate that the prodrug is an additional component, i.e., “further includes”, it appears that the claim is only serving to rename the compound of claim 1 which does not further limit the subject matter thereof. Any inquiry concerning this communication or earlier communications from the examiner should be directed to RAYMOND J HENLEY III whose telephone number is (571)272-0575. The examiner can normally be reached M-F 6-2:30pm EST. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Jeffrey S Lundgren can be reached at 571-272-5541. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /RAYMOND J HENLEY III/Primary Examiner, Art Unit 1629 March 21, 2026
Read full office action

Prosecution Timeline

Jul 28, 2023
Application Filed
Mar 21, 2026
Non-Final Rejection — §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
83%
Grant Probability
86%
With Interview (+2.1%)
2y 0m
Median Time to Grant
Low
PTA Risk
Based on 1248 resolved cases by this examiner. Grant probability derived from career allow rate.

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