Prosecution Insights
Last updated: April 19, 2026
Application No. 18/229,408

DELIVERY SYSTEM FOR A BALLOON-EXPANDABLE TRANSCATHETER VALVE IMPLANTATION

Non-Final OA §103§112
Filed
Aug 02, 2023
Examiner
MANNAN, MIKAIL A
Art Unit
3774
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Braile Biomedica Industria Comercio E Representaco
OA Round
1 (Non-Final)
69%
Grant Probability
Favorable
1-2
OA Rounds
3y 6m
To Grant
92%
With Interview

Examiner Intelligence

Grants 69% — above average
69%
Career Allow Rate
208 granted / 302 resolved
-1.1% vs TC avg
Strong +24% interview lift
Without
With
+23.5%
Interview Lift
resolved cases with interview
Typical timeline
3y 6m
Avg Prosecution
63 currently pending
Career history
365
Total Applications
across all art units

Statute-Specific Performance

§101
1.1%
-38.9% vs TC avg
§103
44.8%
+4.8% vs TC avg
§102
26.2%
-13.8% vs TC avg
§112
21.4%
-18.6% vs TC avg
Black line = Tech Center average estimate • Based on career data from 302 resolved cases

Office Action

§103 §112
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claim Interpretation The following is a quotation of 35 U.S.C. 112(f): (f) Element in Claim for a Combination. – An element in a claim for a combination may be expressed as a means or step for performing a specified function without the recital of structure, material, or acts in support thereof, and such claim shall be construed to cover the corresponding structure, material, or acts described in the specification and equivalents thereof. The following is a quotation of pre-AIA 35 U.S.C. 112, sixth paragraph: An element in a claim for a combination may be expressed as a means or step for performing a specified function without the recital of structure, material, or acts in support thereof, and such claim shall be construed to cover the corresponding structure, material, or acts described in the specification and equivalents thereof. The claims in this application are given their broadest reasonable interpretation using the plain meaning of the claim language in light of the specification as it would be understood by one of ordinary skill in the art. The broadest reasonable interpretation of a claim element (also commonly referred to as a claim limitation) is limited by the description in the specification when 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph, is invoked. As explained in MPEP § 2181, subsection I, claim limitations that meet the following three-prong test will be interpreted under 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph: (A) the claim limitation uses the term “means” or “step” or a term used as a substitute for “means” that is a generic placeholder (also called a nonce term or a non-structural term having no specific structural meaning) for performing the claimed function; (B) the term “means” or “step” or the generic placeholder is modified by functional language, typically, but not always linked by the transition word “for” (e.g., “means for”) or another linking word or phrase, such as “configured to” or “so that”; and (C) the term “means” or “step” or the generic placeholder is not modified by sufficient structure, material, or acts for performing the claimed function. Use of the word “means” (or “step”) in a claim with functional language creates a rebuttable presumption that the claim limitation is to be treated in accordance with 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph. The presumption that the claim limitation is interpreted under 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph, is rebutted when the claim limitation recites sufficient structure, material, or acts to entirely perform the recited function. Absence of the word “means” (or “step”) in a claim creates a rebuttable presumption that the claim limitation is not to be treated in accordance with 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph. The presumption that the claim limitation is not interpreted under 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph, is rebutted when the claim limitation recites function without reciting sufficient structure, material or acts to entirely perform the recited function. Claim limitations in this application that use the word “means” (or “step”) are being interpreted under 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph, except as otherwise indicated in an Office action. Conversely, claim limitations in this application that do not use the word “means” (or “step”) are not being interpreted under 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph, except as otherwise indicated in an Office action. This application includes one or more claim limitations that do not use the word “means,” but are nonetheless being interpreted under 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph, because the claim limitation(s) uses a generic placeholder that is coupled with functional language without reciting sufficient structure to perform the recited function and the generic placeholder is not preceded by a structural modifier. Such claim limitation(s) is/are: “anti-inflation lock mechanism” in claim 1. From the specification paragraph [0020], the “anti-inflation lock mechanism” are interpreted as “a safety device inserted on the balloon line/luer 104 that blocks the passage of fluid and does not allow balloon inflations” and equivalents thereof. “self-centering mechanism” in claim 2. From the specification paragraph [0023], the “self-centering mechanism” is interpreted as being “composed of wires 401 inside the steerable sheath that is triggered in the handle when the valve is positioned in the aortic annulus” and equivalents thereof. Because this/these claim limitation(s) is/are being interpreted under 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph, it/they is/are being interpreted to cover the corresponding structure described in the specification as performing the claimed function, and equivalents thereof. If applicant does not intend to have this/these limitation(s) interpreted under 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph, applicant may: (1) amend the claim limitation(s) to avoid it/them being interpreted under 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph (e.g., by reciting sufficient structure to perform the claimed function); or (2) present a sufficient showing that the claim limitation(s) recite(s) sufficient structure to perform the claimed function so as to avoid it/them being interpreted under 35 U.S.C. 112(f) or pre-AIA 35 U.S.C. 112, sixth paragraph. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claim 12 is rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor, or for pre-AIA the applicant regards as the invention. Claim 12 recites “a steerable sheath”. It is unclear if the recited “steerable sheath” is the same or a different sheath than the previously recited “sheath” in claim 1 from which claim 12 depends. For examination purposes the “steerable sheath” is interpreted as a different sheath than the “sheath” of claim 1. Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102 of this title, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. Claims 1, 4-10 are rejected under 35 U.S.C. 103 as being unpatentable over Syed (WO2022/072509) in view Ramzipoor (US2010/0185270). Regarding claim 1, Syed discloses a delivery system for a balloon-expandable transcatheter valve implantation (Abstract, [0073]), comprising: a sheath (sheath 104) comprising a flared portion (valve sheath 138, where the valve sheath 138 has a larger diameter than the outer diameter of the shaft 104 and therefore is interpreted as being “flared”, [081]) positioned at a tip of the sheath to partially sheathe a transcatheter valve during blood vessel navigation ([078]); and a reinforced balloon catheter shaft (balloon shaft 106) configured to prevent the balloon from kinking within a blood vessel (leg portion 122 is interpreted as reinforcement for the shaft, and have a shore hardness of 75D which would prevent kinking, [066]). Syed does not explicitly disclose an anti-inflation lock mechanism to prevent improper inflation of a balloon. Ramzipoor teaches a catheter with a distal balloon that is guided to a treatment site ([0002]). The catheter having an inflation valve assembly 26 having a stopcock that is operable between a closed and open configuration ([0046]) (where the stopcock has been interpreted as the “the anti-inflation lock mechanism” interpreted under 35 U.S.C. 112(f) by being a structure that can block the passage of fluid). It would have been obvious to one having ordinary skill in the art at the effective filing date of the claimed invention to have modified the delivery system of Syed to include an anti-inflation lock mechanism as taught by Ramzipoor in order to controllably inflate the balloon (Ramzipoor in paragraph [0018] states describes opening the stop to partially inflate the balloon, and closing after which would prevent inflation). Regarding claim 4, Syed/Ramzipoor makes obvious the system of claim 1, Syed further discloses wherein the sheath is configured to house the balloon during an implantation procedure (the sheath 138 covers the balloon of the balloon shaft 106, [079]). Regarding claim 5, Syed/Ramzipoor makes obvious the system of claim 1, the modified invention discloses wherein the anti-inflation lock mechanism is configured to prevent an operator from inflating or expanding the balloon when the balloon is not completely freed up (Ramzipoor teaches the inflation of the balloon being controllable by a stopcock in paragraph [0046], where the stopcock is capable of preventing an operator from inflating the balloon when the balloon is not freed up by having the stopcock in the closed position). Regarding claim 6, Syed/Ramzipoor makes obvious the system of claim 1, Ramzipoor further teaches wherein the anti-inflation lock is configured to be positioned on a balloon luer that blocks passage of fluid to prevent the balloon from inflations ([0016] of Ramzipoor). Regarding claim 7, Syed/Ramzipoor makes obvious the system of claim 1, Syed further discloses wherein the sheath is steerable ([085]) and configured to house a balloon catheter therein (the sheath 138 covers the balloon of the balloon shaft 106, [079]). Regarding claim 8, Syed/Ramzipoor makes obvious the system of claim 7, Syed further discloses wherein the steerable sheath is configured to guide a tip of the balloon ([085]) and support the transcatheter valve ([070]). Regarding claim 9, Syed/Ramzipoor makes obvious the system of claim 7, Syed further discloses further comprising a handle is connected to the balloon catheter and the steerable sheath to allow an operator to flex and move tip of the balloon (handle is intended to flex and guide the balloon the desired site, [085]). Regarding claim 10, Syed/Ramzipoor makes obvious the system of claim 9, Syed further discloses wherein an extension of the balloon catheter (proximal end of tubular portion 197, which extends from balloon catheter 106, [0117], [0118]) crosses inside the handle and ends in a guidewire port (portion 197 extends inside the handle 102 and the guidewire is inserted through handle via 197 and therefore the opening of 197 is interpreted as a guidewire port, [0117], see Fig. 12). Claims 2, 3, 11 are rejected under 35 U.S.C. 103 as being unpatentable over Syed (WO2022/072509) in view Ramzipoor (US2010/0185270) as applied to claim 1, and further in view of Ryan (US2008/0228254). Regarding claims 2 and 3, Syed/Ramzipoor makes obvious the system of claim 1; yet, is silent regarding further comprising a self-centering mechanism configured to center the balloon within an aortic annulus before the implantation procedure, the self-centering mechanism comprises a plurality of wires configured to be pushed outside the sheath to create a cage that accommodates the annulus and forces the balloon to be in a center of the annulus to allow for a central balloon expansion. Ryan teaches a system 302 for deploying a stent, where the system includes petal structures 306 (interpreted as the plurality of wires of self-centering mechanism) ([0098]). The petal structures 306 provide a centering function within an annulus to deploy the stent ([0098]). It would have been obvious to one having ordinary skill in the art at the effective filing date of the claimed invention to have modified the system of Syed/Ramzipoor to include a self-centering mechanism as taught by Ryan in order to improve the delivery of the stent by ensuring the delivery device is centered before deploying the stent ([0098 of Ryan). Regarding claim 11, Syed/Ramzipoor makes obvious the system of claim 1; yet, is silent regarding further comprising a self-centering mechanism comprising a plurality of wires placed inside a steerable sheath configured to be triggered in a handle when transcatheter valve is positioned in an aortic annulus. Ryan teaches a system 302 (steering sheath) for deploying a stent, where the system includes petal structures 306 (interpreted as the plurality of wires of self-centering mechanism) ([0098]). The petal structures 306 provide a centering function within an annulus to deploy the stent ([0098]). It would have been obvious to one having ordinary skill in the art at the effective filing date of the claimed invention to have modified the system of Syed/Ramzipoor to include a self-centering mechanism as taught by Ryan in order to improve the delivery of the stent by ensuring the delivery device is centered before deploying the stent ([0098 of Ryan). Where the sheath is interpreted as steerable by being guided to the target site and where the handle is capable of triggering the plurality of wires by actuating the sheath or another component. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to MIKAIL A MANNAN whose telephone number is (571)270-1879. The examiner can normally be reached M-F 10-6. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Thomas Barrett can be reached on (571)272-4746. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /M.A.M/Examiner, Art Unit 3774 /THOMAS C BARRETT/SPE, Art Unit 3799
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Prosecution Timeline

Aug 02, 2023
Application Filed
Feb 03, 2026
Non-Final Rejection — §103, §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
69%
Grant Probability
92%
With Interview (+23.5%)
3y 6m
Median Time to Grant
Low
PTA Risk
Based on 302 resolved cases by this examiner. Grant probability derived from career allow rate.

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