Prosecution Insights
Last updated: July 17, 2026
Application No. 18/246,943

CELL CULTURE VESSEL, OBSERVATION DEVICE, MICROSCOPE, CULTURE METHOD, AND OBSERVATION METHOD

Final Rejection §102§103
Filed
Jun 26, 2023
Priority
Oct 15, 2020 — JP 2020-173993 +2 more
Examiner
KRCHA, MATTHEW D
Art Unit
1796
Tech Center
1700 — Chemical & Materials Engineering
Assignee
Riken
OA Round
2 (Final)
65%
Grant Probability
Favorable
3-4
OA Rounds
2m
Est. Remaining
99%
With Interview

Examiner Intelligence

Grants 65% — above average
65%
Career Allowance Rate
366 granted / 560 resolved
At TC average
Strong +35% interview lift
Without
With
+35.3%
Interview Lift
resolved cases with interview
Typical timeline
3y 3m
Avg Prosecution
63 currently pending
Career history
631
Total Applications
across all art units

Statute-Specific Performance

§101
0.5%
-39.5% vs TC avg
§103
85.5%
+45.5% vs TC avg
§102
5.3%
-34.7% vs TC avg
§112
4.0%
-36.0% vs TC avg
Black line = Tech Center average estimate • Based on career data from 560 resolved cases

Office Action

§102 §103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Election/Restrictions Applicant’s election without traverse of Group I in the reply filed on 3/3/2026 is acknowledged. Claims 2, 7 and 10-18 are withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to nonelected inventions, there being no allowable generic or linking claim. The examiner notes that claim 7 is dependent upon claim 2 which is one of the non-elected groups and was included in group I as a typo. Therefore, claim 7 is going to be considered to be part of Group II and is considered to be withdrawn. Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 1, 3, 5, 6, 8 and 9 is/are rejected under 35 U.S.C. 102(a)(2) as being anticipated by United States Application Publication No. 2021/0053056, hereinafter Dudokovic. Regarding claim 1, Dudokovic teaches a cell culture vessel (figure 6) comprising a plurality of compartments (each of the tessellated cells as seen in figure 6) each having a corresponding three-dimensional shape (figure 6) and each configured to be able to retain therein an aqueous liquid by surface tension (figure 6, the liquid is contained in some of the tessellated cells), wherein any adjacent compartments out of the plurality of compartments communicate with each other (paragraph [0027). Regarding claim 3, Dudokovic teaches wherein the cell culture vessel has an external form having a polyhedral shape (figure 6), said cell culture vessel further comprising a window part (the opening in each of the tessellated cells which face outwards) which is light-transmissive (figure 6) and which is provided so as to be located at positions that correspond to a respective plurality of faces out of faces of the polyhedral shape (figure 6). Regarding claim 5, Dudokovic teaches wherein the plurality of compartments are placed side by side in at least two directions selected from an X direction, a Y direction, and a Z direction (figure 6). Regarding claim 6, Dudokovic teaches wherein the plurality of compartments are surrounded by a framework corresponding to sides of a hexahedron. Regarding claim 8, these limitations are directed to the function of the apparatus and/or the manner of operating the apparatus, all the structural limitations of the claim has been disclosed by Dudokovic and the apparatus of Dudokovic is capable of having at least some of the plurality of compartments filled with a gel composition including a cell or cell tissue. As such, it is deemed that the claimed apparatus is not differentiated from the apparatus of Dudokovic (see MPEP §2114). Regarding claim 9, these limitations are directed to the function of the apparatus and/or the manner of operating the apparatus, all the structural limitations of the claim has been disclosed by Dudokovic and the apparatus of Dudokovic is capable of having at least some of the plurality of compartments filled with two or more types of the gel composition. As such, it is deemed that the claimed apparatus is not differentiated from the apparatus of Dudokovic (see MPEP §2114). Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. The factual inquiries for establishing a background for determining obviousness under 35 U.S.C. 103 are summarized as follows: 1. Determining the scope and contents of the prior art. 2. Ascertaining the differences between the prior art and the claims at issue. 3. Resolving the level of ordinary skill in the pertinent art. 4. Considering objective evidence present in the application indicating obviousness or nonobviousness. Claim(s) 4 is/are rejected under 35 U.S.C. 103 as being unpatentable over Dudokovic in view of United States Application Publication No. 2019/0002812, hereinafter Hagiwara and United States Application Publication No. 2008/0068707, hereinafter Goodman. Regarding claim 4, Dudokovic teaches wherein the cell culture vessel has an external form having a polyhedral shape (figure 6). However, Dudokovic fails to teach said cell culture vessel further comprising a shaft part which extends, from any of vertices of the polyhedral shape, outward in a direction that is not parallel to any of lines normal to faces of the polyhedral shape. Hagiwara teaches a cell culture vessel which utilizes a pair of tweezers which extends, from any of vertices of the polyhedral shape, outward in a direction that is not parallel to any of lines normal to faces of the polyhedral shape (Hagiwara, figure 6). Goodman teaches that tweezers can be used to manually move a grid from one solution or treatment to the next (Goodman, paragraph [0056]). It would have been obvious to one having ordinary skill in the art before the effective filing date of the claimed invention to have utilized a pair of tweezers (shaft part) which extends, from any of vertices of the polyhedral shape, outward in a direction that is not parallel to any of lines normal to faces of the polyhedral shape because it would allow for the cell culture vessel to be manually moved from one solution or treatment to the next (Goodman, paragraph [0056]). Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to MATTHEW D KRCHA whose telephone number is (571)270-0386. The examiner can normally be reached M-Th 7am-5pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Maris Kessel can be reached at (571)270-7698. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /MATTHEW D KRCHA/ Primary Examiner, Art Unit 1796
Read full office action

Prosecution Timeline

Jun 26, 2023
Application Filed
Apr 09, 2026
Non-Final Rejection mailed — §102, §103
Jun 23, 2026
Response Filed
Jul 16, 2026
Final Rejection mailed — §102, §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
65%
Grant Probability
99%
With Interview (+35.3%)
3y 3m (~2m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 560 resolved cases by this examiner. Grant probability derived from career allowance rate.

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