DETAILED ACTION
Notice of Pre-AIA or AIA Status
The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA .
Priority
The instant application is a 371 National Stage Entry of PCT/IN2021/051015 filed on October 26, 2021 which claims priority to foreign application No. IN202021046675 filed on October 26, 2020.
Status of Claims
Acknowledgement is made of original (12), amended (1, 7, 9-10), previously presented (8, 11, 13), cancelled (2-6), and new (14-16) claims filed December 31, 2025. Claims 1, 7-16 are pending in instant application.
Response to Arguments
Applicant’s amendments filed December 31, 2025 have overcome the following:
The objections to claims 1-7,
The rejection of claims 1-7, 9-10 under 35 U.S.C. 112(b),
The rejection of claims 9-10 under 35 U.S.C. 112(d),
The rejection of claims 1, 5 under 35 U.S.C. 102(a)(1) as being anticipated by Wolf et. al.1, and
The rejection of claims 1, 4, 8-13 under 35 U.S.C. 102(a)(1) as being anticipated by WO 2017/106624 A1 to Gao et. al.2
The above rejections/objects have thus been withdrawn. However, in light of claim amendments, a new rejection under 35 U.S.C. 102(a)(1) has been made.
Claim Interpretation
The phrase in claim 1 “Q is O or -Q-(CH2)n-R is absent” is understood to mean Q may be O, or H is present in lieu of the -Q-(CH2)n-R substituent. In addition, claim 1 states “when R = -COOH, n = 3 to 6” which is understood to mean when R is COOH, -Q-(CH2)n-R is present, and n is 3 to 6.
New Rejections
Claim Rejections - 35 USC § 102
The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action:
A person shall be entitled to a patent unless –
(a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention.
Claim 1 is rejected under 35 U.S.C. 102(a)(1) as being anticipated by STN3.
STN teaches CAS Registry No. 130-15-4 which reads on instant Formula I when -Q-(CH2)n-R is absent, R1, R2, R3 are H, R4 is H, and R6 is H.
CAS# 130-15-4
Instant Formula I
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188
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188
220
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Allowable Subject Matter
Claim 7-16 are objected to as being dependent upon a rejected base claim, but would be allowable if rewritten in independent form including all of the limitations of the base claim and any intervening claims.
Conclusion
Claim 7-16 are objected to.
Claim 1 is rejected.
Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a).
A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action.
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/S.R./Examiner, Art Unit 1627
/JENNIFER A BERRIOS/ Primary Examiner, Art Unit 1613
1 Wolf et. al. "The effect of naphthalene and naphthoquinone derivatives on the activity of (alanine)-aminopeptidase from pig kidneys" Wissenschaftliche Zeitschrift Martin-Luther-Universitaet Halle-Wittenberg, Mathematisch-Naturwissenschaftliche Reihe 1977, 26, 1, 95-102. ISSN: 0138-1504. Hereinafter Wolf.
2 Published June 22, 2017. Hereinafter Gao.
3 CAS 130-15-4. CAS Registry File Accessed February 6, 2026 from STN, entered into STN November 16, 1984. Hereinafter STN.