Prosecution Insights
Last updated: May 29, 2026
Application No. 18/252,416

COMPOSITIONS AND METHODS FOR INHIBITION OF TISSUE ADHESION

Non-Final OA §103§112
Filed
May 10, 2023
Priority
Nov 10, 2020 — provisional 63/111,952 +1 more
Examiner
WASHVILLE, JEFFREY D
Art Unit
1766
Tech Center
1700 — Chemical & Materials Engineering
Assignee
Wayne State University
OA Round
1 (Non-Final)
80%
Grant Probability
Favorable
1-2
OA Rounds
0m
Est. Remaining
75%
With Interview

Examiner Intelligence

Grants 80% — above average
80%
Career Allowance Rate
995 granted / 1245 resolved
+14.9% vs TC avg
Minimal -5% lift
Without
With
+-4.8%
Interview Lift
resolved cases with interview
Typical timeline
2y 8m
Avg Prosecution
36 currently pending
Career history
1288
Total Applications
across all art units

Statute-Specific Performance

§101
0.1%
-39.9% vs TC avg
§103
86.1%
+46.1% vs TC avg
§102
6.6%
-33.4% vs TC avg
§112
2.9%
-37.1% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1245 resolved cases

Office Action

§103 §112
DETAILED ACTION Notice of Pre-AIA or AIA Status 1. The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Information Disclosure Statement 2. The information disclosure statement (IDS) submitted on 5/10/2023 was filed timely. The submission is in compliance with the provisions of 37 CFR 1.97. Accordingly, the information disclosure statement is being considered by the examiner. Election/Restrictions 3. Applicant’s election without traverse of Group 1, claims 15-26, 30 and 32 in the reply filed on 2/4/2026 is acknowledged. Claims 50-55 are withdrawn. Claim Rejections - 35 USC § 112 3. The following is a quotation of 35 U.S.C. 112(d): (d) REFERENCE IN DEPENDENT FORMS.—Subject to subsection (e), a claim in dependent form shall contain a reference to a claim previously set forth and then specify a further limitation of the subject matter claimed. A claim in dependent form shall be construed to incorporate by reference all the limitations of the claim to which it refers. 4. Claims 15-18, 21, 24 and 32 rejected under 35 U.S.C. 112(d) as being of improper dependent form for failing to further limit the subject matter of the claim upon which it depends, or for failing to include all the limitations of the claim upon which it depends. The above noted claims do not claim additional repeat units, but appears to replace units from claim 15 that is improper. Applicant may cancel the claim(s), amend the claim(s) to place the claim(s) in proper dependent form, rewrite the claim(s) in independent form, or present a sufficient showing that the dependent claim(s) complies with the statutory requirements. Claim Rejections - 35 USC § 103 5. In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. 6. The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. 7. Claims 15-26, 30 and 32 are rejected under 35 U.S.C. 103 as being unpatentable over (WO 2016/138528 A1) to Cao et al. (hereinafter Cao). Cao is directed toward biocompatible zwitterionic gels for implant. Cao discloses [00214] that the major component of the gel is water. Cao discloses [0047] that the zwitterionic polymer is in the form of a liquid. Cao discloses [0016] of Formula (III) below: PNG media_image1.png 284 481 media_image1.png Greyscale That reads on Applicants Formula (IV) and Formula (I). Cao discloses [0020] of Formula (IV) below: PNG media_image2.png 341 495 media_image2.png Greyscale That reads on Applicants Formula (II) and Formula (I). Cao discloses at paragraph [0028] of Formula (V) and (VI) below: PNG media_image3.png 396 552 media_image3.png Greyscale That reads on Applicants Formula (XI). It would be obvious to one skilled in the art at the time of filing of the disclosure of Cao to select an anti-adhesive compound that forms a prime facie case of obviousness for claims 15-26, 30 and 32. Conclusion 8. Any inquiry concerning this communication or earlier communications from the examiner should be directed to JEFFREY D WASHVILLE whose telephone number is (571)270-3262. The examiner can normally be reached M-F 9-5. 9. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. 10. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Randy Gulakowski can be reached at 571-272-1302. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. 11. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /JEFFREY D WASHVILLE/Primary Examiner, Art Unit 1766
Read full office action

Prosecution Timeline

May 10, 2023
Application Filed
May 20, 2026
Non-Final Rejection mailed — §103, §112 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
80%
Grant Probability
75%
With Interview (-4.8%)
2y 8m (~0m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1245 resolved cases by this examiner. Grant probability derived from career allowance rate.

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