Prosecution Insights
Last updated: April 19, 2026
Application No. 18/252,964

FOOD COMPRISING ISOSTEVIOL AND USES THEREOF

Final Rejection §102
Filed
May 15, 2023
Examiner
JACOBSON, MICHELE LYNN
Art Unit
1793
Tech Center
1700 — Chemical & Materials Engineering
Assignee
Isofirms Aps
OA Round
2 (Final)
25%
Grant Probability
At Risk
3-4
OA Rounds
4y 2m
To Grant
57%
With Interview

Examiner Intelligence

Grants only 25% of cases
25%
Career Allow Rate
86 granted / 342 resolved
-39.9% vs TC avg
Strong +32% interview lift
Without
With
+31.7%
Interview Lift
resolved cases with interview
Typical timeline
4y 2m
Avg Prosecution
53 currently pending
Career history
395
Total Applications
across all art units

Statute-Specific Performance

§101
1.2%
-38.8% vs TC avg
§103
47.7%
+7.7% vs TC avg
§102
18.3%
-21.7% vs TC avg
§112
22.8%
-17.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 342 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claims 57, 58, 61 and 67-75 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Jeppesen USPGPub 20160074424. Regarding claims 57, 58, 61 and 67-69, Jeppesen teaches the use of isosteviol in a composition comprising 15-150 g protein [0060] and 500 mg isosteviol. [0060,0045,0087] This composition anticipates the recited composition comprising isosteviol and at least 30 wt% protein. Jeppesen discloses administering the composition to human athletes that have been subjected to exhaustive exercise as recited in claims 58 and 68. [0092,0093] Page 39 of applicant’s specification states “it can be concluded that adding isosteviol to a food product can increase the amount of muscles and therefore also increase muscle/fat ratio”. Therefore, the method of providing isosteviol disclosed by Jeppesen would necessarily increase the muscle to fat ratio of an animal as recited in claims 57, 61, 67 and 69. As such, Jeppesen anticipates claims 57, 58, 61 and 67-69. Regarding claim 70, the embodiment of Jeppesen having only protein and isosteviol is interpreted to be a “feed” as recited in claim 70 because it can be fed to a subject. Regarding claims 71-73, the embodiment of Jeppesen consisting of 15 g protein and 500 mg isosteviol comprises 3wt% isosteviol. Regarding claims 74 and 75, providing the food comprising isosteviol of Jeppesen to an athlete as disclosed by Jeppesen prevents or alleviates diarrhea since as disclosed in applicant’s specification (pg. 2) “Isosteviol prevents and/or treats diarrhea. Response to Arguments Applicant's arguments filed 14 November 2025 have been fully considered but they are not persuasive. Applicant asserts on page 8 of the remarks that the proportions relied on in the rejection do not constitute an embodiment without any information related to the total amount of the composition. This assertion fails to appreciate that the embodiment relied on is one consisting of only protein and isosteviol. This embodiment is clearly encompassed by the disclosure of Jeppesen and would have been at once envisaged by one or ordinary skill in the art given the citations provided in the rejection. Clearly, a product consisting of 15-150 g and 0.5 g isosteviol has a protein content as recited in the instant claims. Applicant references embodiments of Jeppesen that comprise carbohydrate on page 8 of the remarks, however, these assertions are not germane as the rejection does not rely on those embodiments. A reference may be relied upon for all that it would have reasonably suggested to one having ordinary skill in the art, including nonpreferred embodiments. Merck & Co. v. Biocraft Labs., Inc. 874 F.2d 804, 10 USPQ2d 1843 (Fed. Cir. 1989), cert. denied, 493 U.S. 975 (1989). See also Upsher-Smith Labs. v. Pamlab, LLC, 412 F.3d 1319, 1323, 75 USPQ2d 1213, 1215 (Fed. Cir. 2005) (reference disclosing optional inclusion of a particular component teaches compositions that both do and do not contain that component) (MPEP 2123) Applicant’s assertions on pages 8-11 of the remarks regarding obviousness and secondary considerations are not germane to the instantly pending rejections under 35 U.S.C. 102 and are therefore not found persuasive. Conclusion Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to Michele L Jacobson whose telephone number is (571)272-8905. The examiner can normally be reached Monday through Friday from 10-6. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Emily Le can be reached at (571) 272-0903. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /Michele L Jacobson/Primary Examiner, Art Unit 1793
Read full office action

Prosecution Timeline

May 15, 2023
Application Filed
Aug 12, 2025
Non-Final Rejection — §102
Nov 14, 2025
Response Filed
Jan 28, 2026
Final Rejection — §102 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

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METHOD FOR PRODUCING BIOMASS USING HYDROGEN-OXIDIZING BACTERIA
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Patent 12543765
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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
25%
Grant Probability
57%
With Interview (+31.7%)
4y 2m
Median Time to Grant
Moderate
PTA Risk
Based on 342 resolved cases by this examiner. Grant probability derived from career allow rate.

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