Prosecution Insights
Last updated: May 29, 2026
Application No. 18/253,094

ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4

Non-Final OA
Filed
May 16, 2023
Priority
Nov 18, 2020 — provisional 63/115,477 +1 more
Examiner
SOLOLA, TAOFIQ A
Art Unit
1625
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
VANDERBILT UNIVERSITY
OA Round
1 (Non-Final)
75%
Grant Probability
Favorable
1-2
OA Rounds
0m
Est. Remaining
92%
With Interview

Examiner Intelligence

Grants 75% — above average
75%
Career Allowance Rate
1095 granted / 1464 resolved
+14.8% vs TC avg
Strong +17% interview lift
Without
With
+16.9%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 0m
Avg Prosecution
10 currently pending
Career history
1473
Total Applications
across all art units

Statute-Specific Performance

§101
2.3%
-37.7% vs TC avg
§103
42.1%
+2.1% vs TC avg
§102
6.4%
-33.6% vs TC avg
§112
13.8%
-26.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1464 resolved cases

Prosecution Timeline

May 16, 2023
Application Filed
Sep 04, 2025
Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12624318
CLEANING AGENT COMPOSITION AND CLEANING METHOD
4y 8m to grant Granted May 12, 2026
Patent 12624000
PROCESS FOR SULFONATION OF 2-AMINOETHANOL HYDROGEN SULFATE ESTER TO PRODUCE TAURINE
3y 5m to grant Granted May 12, 2026
Patent 12612415
STEREOSELECTIVE PROCESS FOR PREPARING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES
4y 2m to grant Granted Apr 28, 2026
Patent 12606547
PREPARATION METHOD OF PHENYLISOXAZOLINE COMPOUND
3y 3m to grant Granted Apr 21, 2026
Patent 12595242
PROCESS AND DEVICE FOR PREPARING TRIOXANE FROM METHANOL
3y 9m to grant Granted Apr 07, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
75%
Grant Probability
92%
With Interview (+16.9%)
2y 0m (~0m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1464 resolved cases by this examiner. Grant probability derived from career allowance rate.

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