Prosecution Insights
Last updated: August 06, 2026
Application No. 18/253,173

CHEMICAL COMPOSITIONS PROVIDING LONG-LASTING SKIN PH CONTROL FOR IMPROVING SKIN-BARRIER FUNCTION AND TREATMENT OF SKIN-BARRIER DISORDERS

Non-Final OA §112
Filed
May 16, 2023
Priority
Apr 26, 2021 — provisional 63/179,998 +2 more
Examiner
FIEBIG, RUSSELL G
Art Unit
1655
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Soteri Skin Inc.
OA Round
3 (Non-Final)
63%
Grant Probability
Moderate
3-4
OA Rounds
0m
Est. Remaining
88%
With Interview

Examiner Intelligence

Grants 63% of resolved cases
63%
Career Allowance Rate
555 granted / 886 resolved
+2.6% vs TC avg
Strong +25% interview lift
Without
With
+25.4%
Interview Lift
resolved cases with interview
Typical timeline
3y 0m
Avg Prosecution
57 currently pending
Career history
935
Total Applications
across all art units

Statute-Specific Performance

§101
11.7%
-28.3% vs TC avg
§103
41.3%
+1.3% vs TC avg
§102
8.2%
-31.8% vs TC avg
§112
30.2%
-9.8% vs TC avg
Black line = Tech Center average estimate • Based on career data from 886 resolved cases

Office Action

§112
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . A request for continued examination under 37 CFR 1.114, including the fee set forth in 37 CFR 1.17(e), was filed in this application after final rejection. Since this application is eligible for continued examination under 37 CFR 1.114, and the fee set forth in 37 CFR 1.17(e) has been timely paid, the finality of the previous Office action has been withdrawn pursuant to 37 CFR 1.114. Applicant's submission filed on 6 May 2026 has been entered. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claims 1, 7-15, 17-25, 27, 30, 31 and 33 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Claim 1 is rendered vague and indefinite by the phrase “wherein at least one acid has a pKa between 4.4 and 5.2, at least one acid has a pKa between 5.3 and 6.5, and at least one acid has a pKa between 3.7 and 4.3.” This language is confusing in light of the added language to the amended claim which recites the pKa values of the specific acids in the buffer system. That is – the phrase would appear to be redundant language. Claim 7 has been amended to remove “claim 6”, but does not replace it with another claim. Claim 8 is rendered vague and indefinite by the phrase “comprising a plurality of acids comprising one or more carboxylic acid groups, wherein at least one acid has a pKa around 4.7, at least one acid has a pKa between 4.7 and 6.5, and at least one acid has a pKa between 3 and 4.7, and wherein each acid has a molecular weight of at least 140”. It is unclear how this is meant to further limit independent claim 1. Does “a plurality of acids” refer to additional acids or those recited in claim 1? Claim 9 is rendered vague and indefinite by the phrase “wherein the plurality of acids comprises at least one of ferulic acid, gluconic acid, and citric acid, or a combination thereof”. This would seem to be the same claim as amended claim 7. Claim 23 is unclear how this actually further limits claim 1, which already contains citric acid and sodium citrate. All other claims depend directly or indirectly from rejected claims and are, therefore, also rejected under U.S.C. 112, second paragraph, for the reasons set forth above. Note: It is suggested to Applicant to carefully review the language of the claims, particularly the dependent claims, in light of the amendments made to independent claim 1. Conclusion No claims are allowed. Any inquiry concerning this communication or earlier communications from the examiner should be directed to RUSSELL G FIEBIG whose telephone number is (571)270-5366. The examiner can normally be reached M-F 8-4. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Anand Desai can be reached at 5712720947. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /RUSSELL G FIEBIG/Examiner, Art Unit 1655
Read full office action

Prosecution Timeline

Show 5 earlier events
Feb 24, 2026
Response Filed
Mar 23, 2026
Final Rejection mailed — §112
Apr 02, 2026
Interview Requested
Apr 08, 2026
Examiner Interview Summary
Apr 08, 2026
Applicant Interview (Telephonic)
May 06, 2026
Request for Continued Examination
May 07, 2026
Response after Non-Final Action
Jun 04, 2026
Non-Final Rejection mailed — §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
63%
Grant Probability
88%
With Interview (+25.4%)
3y 0m (~0m remaining)
Median Time to Grant
High
PTA Risk
Based on 886 resolved cases by this examiner. Grant probability derived from career allowance rate.

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