Prosecution Insights
Last updated: October 02, 2026
Application No. 18/258,343

Therapeutic RNA for Treating Cancer

Final Rejection
Filed
Jun 20, 2023
Priority
Dec 21, 2020 — EU PCT/EP2020/087468 +2 more
Examiner
PUTTLITZ, KARL J
Art Unit
1646
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Biontech SE
OA Round
2 (Final)
69%
Grant Probability
Favorable
3-4
OA Rounds
0m
Est. Remaining
88%
With Interview

Examiner Intelligence

Grants 69% — above average
69%
Career Allowance Rate
990 granted / 1432 resolved
+9.1% vs TC avg
Strong +19% interview lift
Without
With
+18.6%
Interview Lift
resolved cases with interview
Typical timeline
2y 6m
Avg Prosecution
62 currently pending
Career history
1487
Total Applications
across all art units

Statute-Specific Performance

§101
1.6%
-38.4% vs TC avg
§103
36.6%
-3.4% vs TC avg
§102
11.3%
-28.7% vs TC avg
§112
28.3%
-11.7% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1432 resolved cases

Prosecution Timeline

Jun 20, 2023
Application Filed
Mar 23, 2026
Non-Final Rejection mailed
Jun 03, 2026
Response Filed
Aug 17, 2026
Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12741039
Urokinase Plasminogen Activator Receptor-Targeted Radiopharmaceutical
4y 4m to grant Granted Sep 22, 2026
Patent 12734244
ANTIBODY-DRUG CONJUGATES AND THEIR USES
2y 0m to grant Granted Sep 15, 2026
Patent 12723130
DIOL COMPOSITION AND POLYESTER
6y 3m to grant Granted Sep 01, 2026
Patent 12721906
KIDNEY TARGETED DELIVERY OF DRUGS
3y 4m to grant Granted Sep 01, 2026
Patent 12721893
Antigen-Binding Protein Targeting CD70 and Use Thereof
3y 3m to grant Granted Sep 01, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
69%
Grant Probability
88%
With Interview (+18.6%)
2y 6m (~0m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 1432 resolved cases by this examiner. Grant probability derived from career allowance rate.

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