Prosecution Insights
Last updated: October 02, 2026
Application No. 18/260,721

USP13 INHIBITORS AND METHODS OF USE THEREOF

Non-Final OA §102
Filed
Jul 07, 2023
Priority
Jan 14, 2021 — provisional 63/137,425 +1 more
Examiner
CHONG, YONG SOO
Art Unit
1623
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Georgetown University
OA Round
1 (Non-Final)
44%
Grant Probability
Moderate
1-2
OA Rounds
8m
Est. Remaining
85%
With Interview

Examiner Intelligence

Grants 44% of resolved cases
44%
Career Allowance Rate
389 granted / 888 resolved
-16.2% vs TC avg
Strong +42% interview lift
Without
With
+41.6%
Interview Lift
resolved cases with interview
Typical timeline
3y 10m
Avg Prosecution
51 currently pending
Career history
950
Total Applications
across all art units

Statute-Specific Performance

§101
1.1%
-38.9% vs TC avg
§103
53.0%
+13.0% vs TC avg
§102
21.3%
-18.7% vs TC avg
§112
17.3%
-22.7% vs TC avg
Black line = Tech Center average estimate • Based on career data from 888 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Status of the Application Applicant's election of Group I, drawn to a compound of formula I, and the species (BK50118-C) in the reply filed on 2/11/26 is acknowledged. Because applicant did not distinctly and specifically point out the supposed errors in the restriction requirement, the election has been treated as an election without traverse (MPEP § 818.01(a)). Claims 1, 6-8, 11-12, 41-53 are pending. Claims 1, 6-8, 11-12 have been amended. Claims 43-45, 47-53 have been withdrawn from further consideration as being drawn to a non-elected species. Claims 1, 6-8, 11-12, 41-42, 46 are examined herein insofar as they read on the elected invention and species. A search has been performed on the elected species (BK50118-C), which was found free of the prior art. The search will now be expanded and another species will be selected for examination. With regard to the expanded species selected by examiner for examination, claims 8, 12, 42-53 have been withdrawn from further consideration as being drawn to a non-elected species. Claims 1, 6-7, 11, 41 are examined herein insofar as they read on the elected invention and the expanded species. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale or otherwise available to the public before the effective filing date of the claimed invention. Claims 1, 6-7, 11, 41 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Arnold et al. (US Patent 5,145,843). Teaches compound 6,8-difluoro-4-(4-fluorophenoxy)-quinoline (example 201 in Table 5). PNG media_image1.png 194 292 media_image1.png Greyscale Claim Objections Claim 12 is objected to as being dependent upon a rejected base claim, but would be allowable if rewritten in independent form including all of the limitations of the base claim and any intervening claims. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to Yong S. Chong whose telephone number is (571)-272-8513. The examiner can normally be reached Monday to Friday: 9 AM to 5 PM EST. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Adam Milligan, can be reached at (571)-270-7674. The fax phone number for the organization where this application or proceeding is assigned is (571)-273-8300. Information regarding the status of an application may be obtained from the Patent Application Information Retrieval (PAIR) system. Status information for published applications may be obtained from either Private PAIR or Public PAIR. Status information for unpublished applications is available through Private PAIR only. For more information about the PAIR system, see http://pair-direct.uspto.gov. Should you have questions on access to the Private PAIR system, contact the Electronic Business Center (EBC) at (866)-217-9197 (toll-free). /Yong S. Chong/Primary Examiner, Art Unit 1623
Read full office action

Prosecution Timeline

Jul 07, 2023
Application Filed
May 14, 2026
Non-Final Rejection mailed — §102 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
44%
Grant Probability
85%
With Interview (+41.6%)
3y 10m (~8m remaining)
Median Time to Grant
Low
PTA Risk
Based on 888 resolved cases by this examiner. Grant probability derived from career allowance rate.

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