Prosecution Insights
Last updated: May 29, 2026
Application No. 18/264,670

THIENOPYRROLE COMPOUNDS

Final Rejection §102
Filed
Aug 08, 2023
Priority
Feb 09, 2021 — provisional 63/147,641 +2 more
Examiner
AULAKH, CHARANJIT
Art Unit
1621
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Gilead Sciences Inc.
OA Round
2 (Final)
81%
Grant Probability
Favorable
3-4
OA Rounds
0m
Est. Remaining
65%
With Interview

Examiner Intelligence

Grants 81% — above average
81%
Career Allowance Rate
1422 granted / 1758 resolved
+20.9% vs TC avg
Minimal -16% lift
Without
With
+-15.6%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 0m
Avg Prosecution
46 currently pending
Career history
1800
Total Applications
across all art units

Statute-Specific Performance

§101
2.3%
-37.7% vs TC avg
§103
18.5%
-21.5% vs TC avg
§102
21.4%
-18.6% vs TC avg
§112
27.8%
-12.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1758 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . According to paper filed on April 15, 2026, the applicants have canceled claims 2, 4, 8, 19 and 164; amended claims 1, 9, 150 and 154 and furthermore, have added new claim 190. Claims 1, 9, 15, 20-21, 31, 144, 149-157, 161, 167-168 and 190 are pending in the application. Response to Arguments Applicant’s arguments, see paper, filed April 15, 2026, with respect to claims 1, 9, 15, 20-21, 31, 144, 149-157, 161 and 167-168 have been fully considered and are persuasive. The applicants have amended claims to overcome all rejections. NEW GROUNDS OF REJECTION Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim 190 is rejected under 35 U.S.C. 102(a) (1) as being anticipated by Heinrich (U.S. Patent 8,703,961). Heinrich discloses thiazole derivatives. The compounds A14 (see col. 75) and A30 (see col. 83) disclosed by Heinrich anticipate the instant claims when variable X represents N and variable Z represents 6-membered heteroaryl group in the instant compounds of formula I. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention. Claim 190 is rejected under 35 U.S.C. 102(a) (2) as being anticipated by Ku 2021/067326 A1, cited on applicant’s form 1449). Kumar discloses substituted bicyclic heterocyclic compounds. The compound 290 A (see page 171) and compounds of examples 300-307 (see pages 174-179) disclosed by Kumar anticipate the instant claims when variable X represents N and variable Z represents 7-10-membered spirocyclic heterocycle group in the instant compounds of formula I. Allowable Subject Matter Claims 1, 9, 15, 20-21, 31, 144, 149-157, 161 and 167-168 are allowed. Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to CHARANJIT AULAKH whose telephone number is (571)272-0678. The examiner can normally be reached Monday-Friday 7:00-3:30. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Clinton A Brooks can be reached at 571-270-7682. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /CHARANJIT AULAKH/ Primary Examiner, Art Unit 1621
Read full office action

Prosecution Timeline

Aug 08, 2023
Application Filed
Jan 16, 2026
Non-Final Rejection mailed — §102
Apr 15, 2026
Response Filed
May 06, 2026
Final Rejection mailed — §102 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
81%
Grant Probability
65%
With Interview (-15.6%)
2y 0m (~0m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 1758 resolved cases by this examiner. Grant probability derived from career allowance rate.

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