DETAILED ACTION
Notice of Pre-AIA or AIA Status
The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA .
According to paper filed on April 15, 2026, the applicants have canceled claims 2, 4, 8, 19 and 164; amended claims 1, 9, 150 and 154 and furthermore, have added new claim 190.
Claims 1, 9, 15, 20-21, 31, 144, 149-157, 161, 167-168 and 190 are pending in the application.
Response to Arguments
Applicant’s arguments, see paper, filed April 15, 2026, with respect to claims 1, 9, 15, 20-21, 31, 144, 149-157, 161 and 167-168 have been fully considered and are persuasive. The applicants have amended claims to overcome all rejections.
NEW GROUNDS OF REJECTION
Claim Rejections - 35 USC § 102
The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action:
A person shall be entitled to a patent unless –
(a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention.
Claim 190 is rejected under 35 U.S.C. 102(a) (1) as being anticipated by Heinrich (U.S. Patent 8,703,961).
Heinrich discloses thiazole derivatives. The compounds A14 (see col. 75) and A30 (see col. 83) disclosed by Heinrich anticipate the instant claims when variable X represents N and variable Z represents 6-membered heteroaryl group in the instant compounds of formula I.
The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action:
A person shall be entitled to a patent unless –
(a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention.
Claim 190 is rejected under 35 U.S.C. 102(a) (2) as being anticipated by Ku 2021/067326 A1, cited on applicant’s form 1449).
Kumar discloses substituted bicyclic heterocyclic compounds. The compound 290 A (see page 171) and compounds of examples 300-307 (see pages 174-179) disclosed by Kumar anticipate the instant claims when variable X represents N and variable Z represents 7-10-membered spirocyclic heterocycle group in the instant compounds of formula I.
Allowable Subject Matter
Claims 1, 9, 15, 20-21, 31, 144, 149-157, 161 and 167-168 are allowed.
Applicant's amendment necessitated the new ground(s) of rejection presented in this Office action. Accordingly, THIS ACTION IS MADE FINAL. See MPEP § 706.07(a). Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a).
A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action.
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/CHARANJIT AULAKH/ Primary Examiner, Art Unit 1621