Prosecution Insights
Last updated: April 19, 2026
Application No. 18/281,038

ANTI-VIRAL COMPOUNDS

Non-Final OA §102
Filed
Sep 08, 2023
Examiner
SHAMEEM, GOLAM M
Art Unit
1621
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Infex Therapeutics Limited
OA Round
1 (Non-Final)
87%
Grant Probability
Favorable
1-2
OA Rounds
2y 1m
To Grant
99%
With Interview

Examiner Intelligence

Grants 87% — above average
87%
Career Allow Rate
760 granted / 875 resolved
+26.9% vs TC avg
Strong +16% interview lift
Without
With
+15.9%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 1m
Avg Prosecution
20 currently pending
Career history
895
Total Applications
across all art units

Statute-Specific Performance

§101
0.3%
-39.7% vs TC avg
§103
4.9%
-35.1% vs TC avg
§102
19.8%
-20.2% vs TC avg
§112
23.3%
-16.7% vs TC avg
Black line = Tech Center average estimate • Based on career data from 875 resolved cases

Office Action

§102
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . DETAILED ACTION Priority PNG media_image1.png 20 338 media_image1.png Greyscale , is acknowledged. Status of Claims Claims 1-16 and 22-25 are currently pending in the application. Claims 17-21 were canceled. Receipt is acknowledged of amendment / response filed on January 26, 2026 and that has been entered. Information Disclosure Statement Receipt is acknowledged of Information Disclosure Statement (IDS), filed on 01/26/2026, which has been entered in the file. Response to Election/Restriction In response to the restriction requirement, Applicants have elected Group I, which includes claims 1-16, drawn to a compound of formula (I) or a pharmaceutically acceptable salt thereof and the elected species as set forth and found to a compound, such as, PNG media_image2.png 144 200 media_image2.png Greyscale , without traverse, is acknowledged. Claims 22-25 are withdrawn from further consideration pursuant to 37 C.F.R. 1.142 (b) as being drawn to a non-elected subject matters and therefore, the requirement for restriction is still deemed proper made it final. Applicants preserve their right to file a divisional on the non-elected subject matter. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale or otherwise available to the public before the effective filing date of the claimed invention. (a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention. Claims 1-16 are rejected under 35 U.S.C. § 102(a)(1) as being anticipated by Lehmann et al (2009). Applicant claims anti-viral compound of formula (I), pharmaceutical compositions and their method of uses thereof. Lehmann et al also disclose several identical compounds and compositions, which anticipate the instantly claimed inventions [ PNG media_image3.png 112 146 media_image3.png Greyscale , where X1-X5 are C, R5 = phenyl; Y = C=O; R3 = H; R1 = C2 alkylene R1a, with R1a = NR6R7; where R6 and R7 are C1 alkyl; L1 is absent; R2 = phenyl with R8 (halo), Figure 1, page 4657, a copy is provided with this Office action]. Claims 1-16 are also rejected under 35 U.S.C. § 102(a)(1) as being anticipated by Lu et al (2014). Applicant claims anti-viral compound of formula (I), pharmaceutical compositions and their method of uses thereof. Lu et al also disclose several identical compounds and compositions, which anticipate the instantly claimed inventions [ PNG media_image4.png 90 150 media_image4.png Greyscale , the amines at bottom of page 353, where L = meta substituted phenyl, and the amine is the N-CH(CH3)Ph, amine like compound 23, pages 353-355, a copy is provided with this Office action]. Objections The disclosure is objected to because it contains an embedded hyperlink and/or other form of browser-executable code (The specification contains a hyperlink at [007]). Applicant is required to delete the embedded hyperlink and/or other form of browser-executable code; references to websites should be limited to the top-level domain name without any prefix such as http:// or other browser-executable code. See MPEP § 608.01. Telephone Inquiry Any inquiry concerning this communication or earlier communications from the examiner should be directed to Golam Shameem, Ph.D. whose telephone number is (571) 272-0706. The examiner can normally be reached on Monday-Thursday from 7:30 AM - 6:00 PM. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Clinton Brooks, Ph.D. can be reached at (571) 270-7682. Information regarding the status of an application may be obtained from the Patent Application Information Retrieval (PAIR) system. Status information for published applications may be obtained from either Private PAIR or Public PAIR. Status information for unpublished applications is available through Private PAIR only. For more information about the PAIR system, see http://portal.uspto.gov/external/portal. Should you have questions about access to the Private PAIR system, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). Any inquiry of a general nature or relating to the status of this application should be directed to the Group receptionist, whose telephone number is (571) 272-1600. /GOLAM M SHAMEEM/Primary Examiner, Art Unit 1621
Read full office action

Prosecution Timeline

Sep 08, 2023
Application Filed
Mar 25, 2026
Non-Final Rejection — §102 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12589087
ENANTIOMER SELECTIVE ACTION ON NEUROTRANSMISSION
2y 5m to grant Granted Mar 31, 2026
Patent 12583851
HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES
2y 5m to grant Granted Mar 24, 2026
Patent 12583820
BROAD SPECTRUM ANTIVIRALS AGAINST CORONAVIRUS
2y 5m to grant Granted Mar 24, 2026
Patent 12583830
SYNTHESIS METHOD FOR SYNTHESIZING OXETANE DERIVATIVE BY MICROREACTOR
2y 5m to grant Granted Mar 24, 2026
Patent 12583822
BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF
2y 5m to grant Granted Mar 24, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
87%
Grant Probability
99%
With Interview (+15.9%)
2y 1m
Median Time to Grant
Low
PTA Risk
Based on 875 resolved cases by this examiner. Grant probability derived from career allow rate.

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