Notice of Pre-AIA or AIA Status
The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claims 1-2, 4-5 and 8-14 are pending in this application.
Election/Restrictions
Applicant’s election without traverse of Group II in the reply filed on 02/03/2026 is acknowledged.
Claim Rejections - 35 USC § 112
The following is a quotation of 35 U.S.C. 112(b):
(b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention.
The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph:
The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention.
Claims 1-2 and 8 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Claim 1 and claims dependent thereon are rejected because the definition of R10 is not clear. Applicants define R10 as an alkylamine -containing residue, a glycine residue, a lysine residue; and a D-serine residue, but it is unclear what the residue looks like or how it is connected the carbonyl C(O). What is covered by the “residue” and what is not? In order to overcome this rejection, it is recommended that applicants recite specific substituents for variable R10 according to pages 35-36 of the specification or based on the disclosed compounds e.g. R10 = CH(NH2)-(CH2)4-NH2 (see compound 4), CH(NH2)-CH2-OH (compound 6), etc.
Allowable Subject Matter
Claim 5 is allowed.
Objection
Claim 4 is objected to as being dependent upon a rejected base claim, but would be allowable if rewritten in independent form including all of the limitations of the base claim and any intervening claims.
Information Disclosure Statement
Applicant’s Information Disclosure Statement, filed on 01/23/2026, 01/15/2026, 09/12/2025 and 02/19/2024 has been acknowledged. Please refer to Applicant’s copies of the 1449 submitted herewith.
In order to expedite prosecution after rejoinder, the examine recommends that applicants delete “such as” and “preventing” from claim 11 and “including” from claim 10.
Conclusion
8. Any inquiry concerning this communication or earlier communications from the examiner should be directed to Kahsay Habte Ph.D. whose telephone number is (571)272-0667. The examiner can normally be reached on 8:30 - 5:00 PM.
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/Kahsay Habte/
Primary Examiner, Art Unit 1624