Prosecution Insights
Last updated: July 17, 2026
Application No. 18/288,741

COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS

Non-Final OA §102
Filed
Oct 27, 2023
Priority
Apr 30, 2021 — continuation of PCTCN2021091425 +2 more
Examiner
SEITZ, ANTHONY JOSEPH
Art Unit
1629
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Chengdu Anticancer Bioscience Ltd.
OA Round
1 (Non-Final)
67%
Grant Probability
Favorable
1-2
OA Rounds
8m
Est. Remaining
94%
With Interview

Examiner Intelligence

Grants 67% — above average
67%
Career Allowance Rate
122 granted / 182 resolved
+7.0% vs TC avg
Strong +27% interview lift
Without
With
+26.9%
Interview Lift
resolved cases with interview
Typical timeline
3y 5m
Avg Prosecution
64 currently pending
Career history
253
Total Applications
across all art units

Statute-Specific Performance

§101
0.6%
-39.4% vs TC avg
§103
37.4%
-2.6% vs TC avg
§102
13.7%
-26.3% vs TC avg
§112
9.8%
-30.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 182 resolved cases

Office Action

§102
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . DETAILED ACTION Election/Restrictions and Status of the Claims Applicant’s election without traverse of Group II, comprising claims 8-15 and 22-23, as well as applicant’s election of ‘Compound 83’ as the single specific compound in the response filed on May 4th 2026 is acknowledged. Claims 1-23 are pending. Claims 1-7 and 16-21 are withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to a nonelected invention, there being no allowable generic or linking claim. Election was made without traverse in the reply filed on May 4th 2026. Claims 8 and 22-23 are examined on their merits. Priority Receipt is acknowledged of certified copies of papers required by 37 CFR 1.55. Information Disclosure Statement The Information Disclosure Statement filed on May 4th 2026 is in compliance with the provisions of 37 CFR 1.97 and has been considered in full. A signed copy of references cited from the IDS is included with this Office Action. Claim Objections Claims 22 and 23 are objected to under 37 CFR 1.75(c) as being in improper form because a multiple dependent claim may not depend on another multiple dependent claim. See MPEP § 608.01(n). For the purpose of examination, claims 22 and 23 will be treated as if they depend solely on claim 8. Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claims 8 and 22-23 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Myers (US Patent No. 5,710,158 issued on January 20th 1998). Claim 8 is directed towards a compound of Formula (II): PNG media_image1.png 190 216 media_image1.png Greyscale . Myers teaches the compound, PNG media_image2.png 372 500 media_image2.png Greyscale (Myers, col. 23). Myers’ compound is equivalent to Formula (II) wherein R4 is OCH3, m is 2, A is -C(H)=, p is 0, Ra is CH3, R3 is OCH3, n=1, and R2 is OCH3. Thus, Myers anticipates claim 8. Claim 22 is directed towards a pharmaceutical composition comprising the compound of claim 8. Myers describes such pharmaceutical compositions (Myers, col. 10-11), anticipating claim 22. Claim 23 is directed towards the treatment of cancer via administration of the compound of claim 8. Myers teaches the inhibition of cell proliferation with the compound (Myers, claim 1), and teaches cancer as one such disease wherein such a treatment would be useful (Myers, col. 1). Myers thereby anticipates claim 23. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to Anthony Seitz whose telephone number is (703)756-4657. The examiner can normally be reached 7:30 AM ET - 5:00 PM ET M-F. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Jeffrey Lundgren can be reached at (571)272-5541. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /ANTHONY JOSEPH SEITZ/Examiner, Art Unit 1629
Read full office action

Prosecution Timeline

Oct 27, 2023
Application Filed
Jun 25, 2026
Non-Final Rejection mailed — §102 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
67%
Grant Probability
94%
With Interview (+26.9%)
3y 5m (~8m remaining)
Median Time to Grant
Low
PTA Risk
Based on 182 resolved cases by this examiner. Grant probability derived from career allowance rate.

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